Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V60066 | (6Z,16Z)-12-((Z)-Dec-4-enyl)docosa-6,16-dien-11-yl 5-(dimethylamino)pentanoate | 1450888-71-7 | Genevant CL1 is an ionizable cationic lipid (lipid 10, pKa=6.3) that can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1][2]. |
|
V77379 | (R)-Chol-TPP | (R)-Chol-TPP is a mitochondria-targeted liposomal ligand for pH-redox reactions. | |
|
V73412 | (Z)-KC02 | 1646795-60-9 | (Z)-KC02 is an inhibitor (blocker/antagonist) of ABHD16A, the phosphatidylserine (PS) lipase that produces lyso-PS. |
|
V84244 | 1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) | 5634-86-6 | |
|
V83376 | 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE; 1,2-Dilauroyl-sn-glycero-3-PE) | 59752-57-7 | |
|
V73459 | 1,2-DImyristoyl-rac-glycero-3-phosphocholine | 18656-38-7 | 1,2-DImyristoyl-rac-glycero-3-phosphocholine (DMPC) is a zwitterionic phospholipid chosen for simple eukaryotic cell membranes, mimicking the neutral charge of the eukaryotic plasma membrane surface. |
|
V74061 | 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC; Dimyristoyl phosphatidylcholine) | 18194-24-6 | 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes and lipid bilayers. |
|
V73466 | 1,2-Dioctanoyl-sn-glycero-3-phosphocholine | 19191-91-4 | 1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid extensively used as a component of liposome formulations and drug delivery systems. |
|
V74058 | 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) | 90693-88-2 | 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium is a phosphoserine/phosphatidylserine alternative. |
|
V73451 | 1,2-Distaroyl-sn-glycero-3-phosphate sodium (distearoylphosphatidic acid) | 108321-18-2 | 1,2-Distaroyl-sn-glycero-3-phosphate, sodium salt is a phospholipid extensively used as a component of liposome formulations and drug delivery systems. |
|
V73457 | 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (DSPG) | 217939-97-4 | 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is a phospholipid used in drug delivery and liposome synthesis. |
|
V74053 | 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) | 816-94-4 | 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (DSPC) is a lipid that may be utilized to prepare liposomes and is the lipid component in lipid nanoparticle (LNP) systems. |
|
V74071 | 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate | 125401-63-0 | 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a lipid. |
|
V77507 | 113-N16B | 113-N16B is an ionizable cationic lipid that may be utilized to prepare lipid nanoparticles. | |
|
V85503 | 16:1 (DELTA 9-Cis) PC (1,2-Dipalmitoleoyl-sn-glycero-3-phosphocholine) | 4724-96-3 | |
|
V73480 | 18:0 DAP | 121315-93-3 | 18:0 DAP may be utilized to prepare lipid nanoparticles (LNPs) with mRNA encapsulated in their core. |
|
V85491 | 18:1 Cardiolipin disodium | 115404-77-8 | |
|
V73438 | 18:1 Ethylene Glycol | 928-24-5 | 18:1 Ethylene Glycol is a liposome used to deliver active molecules. |
|
V82219 | 2-Trifluoromethyl-2'-methoxychalcone | 1309371-03-6 | 2-Trifluoromethyl-2'-methoxychalcone is a chalcone analogue. |
|
V60070 | 306-N16B | 2803699-70-7 | 306-N16B is a lipid nanoparticles that can achieve systematic synergistic delivery of Cas9 mRNA and sgRNA. |
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