Tyrosinase is a copper-containing metalloprotein belonging to the type-3 copper protein family, together with haemocyanins and catechol oxidases.Tyrosinases are the mammalian enzymes that initiate the production of melanin, the pigment that gives skin and hair their color, as well as the browning of fruits and vegetables after cell damage.
Tyrosinases are involved in pigmentation, wound healing, radiation protection, and the initial immune response. They are present in a variety of prokaryotes in addition to plants, fungi, arthropods, and mammals. The hydroxylation of monophenols and the oxidation of diphenols by tyrosinases results in quinones, which spontaneously polymerize to form melanin. Tyrosinases are crucial for wound healing and basic immune responses in plants, sponges, and a variety of invertebrates; they also aid in sclerotization in arthropods; and they shield DNA from UV ray damage in bacteria.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V71954 | (-)-Taxifolin ((-)-Dihydroquercetin; (-)-Dihydroquercetin) | 111003-33-9 | (-)-Taxifolin is the less active isomer of Taxifolin. |
|
V84431 | (±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) | ||
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V87754 | 2-Ketoglutaric acid potassium | 997-43-3 | 2-Ketoglutaric acid potassium (Alpha-Ketoglutaric acid potassium) is an intermediate in the production of ATP or GTP in the Krebs cycle. |
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V71939 | 2-Methoxycinnamic acid | 6099-03-2 | 2-Methoxycinnamic acid is a noncompetitive tyrosinase inhibitor. |
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V71935 | 3-O-Ethyl-L-ascorbic acid (vitamin C ethyl ether) | 86404-04-8 | 3-O-Ethyl-L-ascorbic acid, a stable vitamin C analogue, is a cosmetic tyrosinase inhibitor (antagonist) with whitening ability. |
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V71962 | 4-Ethylresorcinol | 2896-60-8 | 4-Ethylresorcinol is an analogue of resorcinol that serves as a substrate for tyrosinase. |
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V93017 | 4-Prenyloxyresveratrol | 69065-16-3 | 4-Prenyloxy-resveratrol is an oxidized resveratrol derivative with potent tyrosinase inhibitory activity with IC50 of 0.9 μM. |
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V51532 | 5-epi-Arvestonate A | 2767066-84-0 | 5-epi-Arvestonate A is a sesquiterpenoid extracted from Seriphidium transiliense. |
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V71937 | 5-Feruloylquinic acid | 40242-06-6 | 5-Feruloylquinic acid (5-FQA) has antioxidant and tyrosinase inhibitory activities. |
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V87747 | 5-Methylresorcinol monohydrate | 6153-39-5 | 5-Methylresorcinol monohydrate (Orcinol monohydrate) is a tyrosinase inhibitor. |
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V71945 | 6-Hydroxykaempferol | 4324-55-4 | 6-Hydroxykaempferol, a flavonoid, is a competitive tyrosinase inhibitor (antagonist) with IC50 of 124 μM. |
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V71946 | 7-Methoxy obtusifolin | 1820806-09-4 | 7-Methoxy obtusifolin (Compound 4) is a competitive tyrosinase inhibitor (antagonist) with IC50 of 7.0 μM. |
![Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2](http://www.invivochem.com/upload/1124/V71949.png)
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V71949 | Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 | 82188-67-8 | Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 is a melanogen, a hormone that stimulates melanocytes. |
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V87746 | Ailancoumarin E | Ailancoumarin E (Compound 5) is a derivative of Coumarin. | |
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V71963 | Allamadicin | 51838-83-6 | Allamadicin is an iridoid lactone. |
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V16700 | α-Arbutin | 84380-01-8 | α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is a popular and effective skin whitening agent that also works as a tyrosinase inhibitor. |
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V87744 | Aspochalasin I | 670225-69-1 | Aspochalasin I exhibits cytotoxicity against cancer cells NCIH460, MCF-7, and SF-268 with IC50 values of 22.1, 33.4, and 19.9 μM, respectively. |
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V71944 | Azo-resveratrol | 1393556-48-3 | Azo-resveratrol is an azo compound that can inhibit mushroom tyrosinase (IC50=36.28 μM). |
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V71932 | Broussonin C | 76045-49-3 | Broussonin C is a competitive inhibitor of Tyrosinase and can be extracted from Broussonetia kazinoki. |
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V71956 | Chlorogenic acid butyl ester | 132741-56-1 | Chlorogenic acid butyl ester is a caffeoylquinic acid, a potent melanogenesis inhibitor. |
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