E3 Ligase Ligand-Linker Conjugate, which is one part of Proteolysis Targeting Chimeric Molecules (PROTACs), incorporates a ligand for the E3 ubiquitin ligase and a linker.These conjugates can be used to create PROTACs that target proteins for ubiquitination and destruction after being coupled to the ligand for the target protein (for example, JQ1 for the BRD4 protein or Molibresib for the BET protein). Currently, a number of PROTACs that specifically target BET, the estrogen receptor (ER), the androgen receptor, etc. have been identified to demonstrate good biological activity.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V82454 | Amino-PEG6-acetic acid | 1104083-46-6 | Amino-PEG6-acetic acid is a PROTAC (PROteolysis TArgeting Chimera) linker, which belongs to the Polyethylene glycol (PEG) category and may be utilized to prepare PROTAC protein degraders. |
|
V82362 | Amino-PEG7-t-butyl ester | 2428400-07-9 | Amino-PEG7-t-butyl ester is a PROTAC (PROteolysis TArgeting Chimera) linker of the PEG category, may be utilized to prepare PROTAC protein degraders. |
|
V82357 | Antiproliferative agent-22 | 1374305-45-9 | antiproliferation agent-22 (compound 2) is an anticancer agent. |
|
V82412 | Azido-C1-PEG3-C3-NH2 | 1162336-72-2 | Azido-C1-PEG3-C3-NH2 is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG (Polyethylene glycol) class, may be utilized to prepare PROTAC molecules. |
|
V82402 | Azido-PEG3-C6-Cl | 1625717-44-3 | Azido-PEG3-C6-Cl is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG (Polyethylene glycol) class, may be utilized to prepare PROTAC molecules. |
|
V82487 | Azido-PEG4-azide | 182760-73-2 | Azido-PEG4-azide is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG (Polyethylene glycol) class. |
|
V82495 | Azido-PEG5-S-methyl ethanethioate | 1352221-64-7 | Azido-PEG5-S-methyl ethanethioate is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG (Polyethylene glycol) class, may be utilized to prepare PROTAC molecules. |
|
V82421 | Azido-PEG7-CH2COOH | 1446411-32-0 | Azido-PEG7-CH2COOH is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG category, may be utilized to prepare PROTAC molecules. |
|
V82444 | Benzyl-PEG1-propanol | 131326-24-4 | Benzyl-PEG1-propanol is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders. |
|
V82469 | Benzyl-PEG12-alcohol | 2218463-17-1 | Benzyl-PEG12-alcohol is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders. |
|
V82419 | Benzyl-PEG2-acid | 91555-65-6 | Benzyl-PEG2-acid is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders. |
|
V82410 | Benzyl-PEG3-acid | 127457-63-0 | Benzyl-PEG3-acid is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders. |
|
V82446 | Benzyl-PEG4-amine | 86770-76-5 | Benzyl-PEG4-amine is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders. |
|
V82470 | Benzyl-PEG4-Azido | 86770-71-0 | Benzyl-PEG4-Azido is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG (Polyethylene glycol) class. |
|
V82479 | Benzyl-PEG4-Ots | 89346-82-7 | Benzyl-PEG4-Ots is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category. |
|
V82434 | Benzyl-PEG4-THP | 1027926-86-8 | Benzyl-PEG4-THP is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders. |
|
V82407 | Benzyl-PEG5-acid | 2514948-41-3 | Benzyl-PEG5-acid is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders. |
|
V82450 | Benzyl-PEG5-NHBoc | 2064292-55-1 | Benzyl-PEG5-NHBoc is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders. |
|
V82497 | Benzyl-PEG6-amine | 86770-78-7 | Benzyl-PEG6-amine is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders. |
|
V82451 | Benzyl-PEG6-t-butyl ester | 2148296-00-6 | Benzyl-PEG6-t-butyl ester is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders. |
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