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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
2’-Deoxy-N1-methylguanosine V53246 2'-Deoxy-N1-methylguanosine 5132-79-6 2'-Deoxy-N1-methylguanosine is an analogue of purine nucleoside.
2'-Deoxy-N2,N2-diethyl guanosine V56296 2'-Deoxy-N2,N2-diethyl guanosine 236389-19-8 2'-Deoxy-N2,N2-diethyl guanosine is an analogue of purine nucleoside.
2’-Deoxy-N2,N2-dimethylguanosine V55392 2'-Deoxy-N2,N2-dimethylguanosine 88127-22-4 2'-Deoxy-N2,N2-dimethylguanosine is an analogue of purine nucleoside.
2'-Deoxy-N2-cyclopentyl guanosine V75745 2'-Deoxy-N2-cyclopentyl guanosine 1353757-90-0 2'-Deoxy-N2-cyclopentyl guanosine is an analogue of purine nucleoside.
2'-Deoxy-N2-isopropyl guanosine V55839 2'-Deoxy-N2-isopropyl guanosine 201528-73-6 2'-Deoxy-N2-isopropyl guanosine is an analogue of purine nucleoside.
2’-Deoxy-N3-methylcytidine V55276 2'-Deoxy-N3-methylcytidine 5040-21-1 2'-Deoxy-N3-methylcytidine is an analogue of purine nucleoside.
2’-Deoxy-N3-methylcytidine hydriodide V53357 2'-Deoxy-N3-methylcytidine hydriodide 79043-77-9 2'-Deoxy-N3-methylcytidine hydriodide is an analogue of purine nucleoside.
2’-Deoxy-N4,N4-dimethylcytidine V55296 2'-Deoxy-N4,N4-dimethylcytidine 53213-03-9 2'-Deoxy-N4,N4-dimethylcytidine is an analogue of purine nucleoside.
2’-Deoxy-N4-ethyl-5-methylcytidine V55853 2'-Deoxy-N4-ethyl-5-methylcytidine 25406-43-3 2'-Deoxy-N4-ethyl-5-methylcytidine is an analogue of purine nucleoside.
2’-Deoxy-N4-methylcytidine V55976 2'-Deoxy-N4-methylcytidine 22882-02-6 2'-Deoxy-N4-methylcytidine is an analogue of purine nucleoside.
2’-Deoxy-N6-(3-methoxybenzyl)adenosine V55425 2'-Deoxy-N6-(3-methoxybenzyl)adenosine 1947400-98-7 2'-Deoxy-N6-(3-methoxybenzyl)adenosine is an analogue of purine nucleoside.
2'-Deoxy-N6-(4-methoxybenzyl)adenosine V75656 2'-Deoxy-N6-(4-methoxybenzyl)adenosine 157640-47-6 2'-Deoxy-N6-(4-methoxybenzyl)adenosine is an analogue of purine nucleoside.
2'-Deoxy-N6-cyclopentyladenosine V75643 2'-Deoxy-N6-cyclopentyladenosine 170711-45-2 2'-Deoxy-N6-cyclopentyladenosine is an analogue of purine nucleoside.
2'-Deoxy-N6-phenoxyacetyladenosine V55933 2'-Deoxy-N6-phenoxyacetyladenosine 110522-74-2 2'-Deoxy-N6-phenoxyacetyladenosine is an analogue of purine nucleoside.
2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine V55880 2'-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine 86137-72-6 2'-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is an analogue of purine nucleoside.
2′-Deoxy-β-L-uridine V75766 2′-Deoxy-β-L-uridine 31501-19-6 2'-Deoxy-β-L-uridine is a nucleic acid analogue that is a specific substrate for viral enzymes and has no stereospecificity for herpes simplex type 1 (HSV1) thymidine kinase (TK).
2'-Deoxyisocytidine V75732 2'-Deoxyisocytidine 123075-23-0 2'-Deoxyisocytidine is an analogue of purine nucleoside.
2'-Deoxyisoguanosine V55401 2'-Deoxyisoguanosine 106449-56-3 2'-Deoxyisoguanosine is an analogue of purine nucleoside.
2’-dG (iBu)-2’-phosphoramidite V55705 2'-dG (iBu)-2'-phosphoramidite 157327-97-4 2'-dG (iBu)-2'-phosphoramidite is an analogue of purine nucleoside.
2'-F-2'-ara-N2-ibu-dG Phosphoramidite V55572 2'-F-2'-ara-N2-ibu-dG Phosphoramidite 1404463-20-2 2'-F-2'-ara-N2-ibu-dG Phosphoramidite is a guanine nucleoside analog.
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