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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
2,3’-Anhydrothymidine; 2’-Deoxy-3’,2-anhydro-5-methyluridine V55959 2,3'-Anhydrothymidine; 2'-Deoxy-3',2-anhydro-5-methyluridine 15981-92-7 2,3'-Anhydrothymidine; 2'-Deoxy-3',2-anhydro-5-methyluridine is an analogue of purine nucleoside.
2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone (2,3,5-三-O-苄基-D-核糖酸-1,4-内酯) V52942 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone (2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone) 55094-52-5 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is an analogue of purine nucleoside.
2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine V75550 2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine 103884-97-5 2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an adenine nucleoside analogue.
2,6-Dichloro-2',3',5'-triacetyl-purine riboside (2,6-Dichloro-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine) V55846 2,6-Dichloro-2',3',5'-triacetyl-purine riboside (2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl) purine) 3056-18-6 2,6-Dichloro-2',3',5'-triacetyl-purine riboside is an analogue of purine nucleoside.
2,6-Dichloro-9-(2-c-methyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)purine V55333 2,6-Dichloro-9-(2-c-methyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)purine 205171-10-4 2,6-Dichloro-9-(2-c-methyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)purine dibenzoate is an analogue of purine nucleoside.
2,6-Dichloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl)-9H-purine V55551 2,6-Dichloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl)-9H-purine 329187-80-6 2,6-Dichloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl)-9H-purine arabinoriboside is an analogue of purine nucleoside.
2,8-Dimethyladenosine V75713 2,8-Dimethyladenosine 63954-66-5 2,8-Dimethyladenosine is an adenine nucleoside analog.
2-(2,4-Dichlorobenzyl)thioadenosine V75658 2-(2,4-Dichlorobenzyl)thioadenosine 2095417-37-9 2-(2,4-Dichlorobenzyl)thioadenosine is an adenine nucleoside analog.
2-(4-Cyanobenzyl)thioadenosine V55998 2-(4-Cyanobenzyl)thioadenosine 2095417-56-2 2-(4-Cyanobenzyl)thioadenosine is an adenine nucleoside analog.
2-(4-Methylbenzyl)thioadenosine V55596 2-(4-Methylbenzyl)thioadenosine 2095417-16-4 2-(4-Methylbenzyl)thioadenosine is an adenine nucleoside analog.
2-(N,N-Dimethylamino)-N6,N6-dimethyladenosine V55416 2-(N,N-Dimethylamino)-N6,N6-dimethyladenosine 2305415-86-3 2-(N,N-Dimethylamino)-N6,N6-dimethyladenosine is an adenine nucleoside analog.
2-(n-Propylidene hydrazino) adenosine V55801 2-(n-Propylidene hydrazino) adenosine 144348-05-0 2-(n-Propylidene hydrazino)adenosine is an analogue of purine nucleoside.
2-[(3-Pyridyl) pyrrolidin-1-yl]-2’-deoxyinosine V55379 2-[(3-Pyridyl) pyrrolidin-1-yl]-2'-deoxyinosine 882435-02-1 2-[(3-Pyridyl) pyrrolidin-1-yl]-2'-deoxyinosine is an analogue of purine nucleoside.
2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone V75920 2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone 10212-31-4 2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone is an analogue of purine nucleoside.
2-Amino-2',3'-bis-O-(2-methoxyethyl) adenosine V75635 2-Amino-2',3'-bis-O-(2-methoxyethyl) adenosine 847647-19-2 2-Amino-2',3'-bis-O-(2-methoxyethyl) adenosine is an analogue of purine nucleoside.
2-Amino-2′-C-methyladenosine V75577 2-Amino-2′-C-methyladenosine 640725-73-1 2-Amino-2′-C-methyladenosine is an analogue of purine nucleoside.
2-Amino-2’-deoxy-N6,N6-dimethyl-2’-adenosine V55576 2-Amino-2'-deoxy-N6,N6-dimethyl-2'-adenosine 83061-20-5 2-Amino-2'-deoxy-N6,N6-dimethyl-2'-adenosine is an analogue of purine nucleoside.
2-Amino-2'-deoxyadenosine (2,6-二氨基嘌呤-2'-脱氧核苷) V53314 2-Amino-2'-deoxyadenosine (2,6-diaminopurine-2'-deoxynucleoside) 4546-70-7 2-Amino-2'-deoxyadenosine is a deoxyribonucleoside that may be utilized in the preparation /synthesis of oligonucleotides.
2-Amino-2′-O-(2-methoxy-2-oxoethyl)adenosine V75664 2-Amino-2′-O-(2-methoxy-2-oxoethyl)adenosine 433288-71-2 2-Amino-2′-O-(2-methoxy-2-oxoethyl)adenosine is an adenine nucleoside analogue.
2-Amino-3’-deoxy-3’-fluoroadenosine V55622 2-Amino-3'-deoxy-3'-fluoroadenosine 125391-75-5 2-Amino-3'-deoxy-3'-fluoroadenosine is an analogue of purine nucleoside.
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