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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
2-Amino-3’-O-methyladenosine V55932 2-Amino-3'-O-methyladenosine 80791-88-4 2-Amino-3'-O-methyladenosine is an analogue of purine nucleoside.
2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one V75941 2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one 444020-71-7 2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one is an analogue of purine nucleoside.
2-Amino-6-allyl thio-9-(beta-D-ribofuranosyl)-9H-purine V55614 2-Amino-6-allyl thio-9-(beta-D-ribofuranosyl)-9H-purine 92104-54-6 2-Amino-6-allyl thio-9-(beta-D-ribofuranosyl)-9H-purine is an analogue of purine nucleoside.
2-Amino-6-chloro-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine V75965 2-Amino-6-chloro-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine 640725-74-2 2-Amino -6-chloro-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine is an analogue of purine nucleoside.
2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine V55481 2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine 1612192-05-8 2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine ((2R,3S,4S,5R)-2-(2-Amino-6-chloro -9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol) is an analogue of purine nucleoside.
2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine V55939 2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine 1055035-48-7 2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine is an analogue of purine nucleoside.
2-Amino-6-chloro-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-beta-D-ribofuranosyl)]-9H-purine V75724 2-Amino-6-chloro-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-beta-D-ribofuranosyl)]-9H-purine 641571-44-0 2-Amino-6-chloro-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-beta-D-ribofuranosyl)]-9H-purine dibenzoate is an adenine nucleoside analog things.
2-Amino-6-chloropurine-3’,5’-di-O-acetyl-2’-deoxyriboside V55833 2-Amino-6-chloropurine-3',5'-di-O-acetyl-2'-deoxyriboside 69992-11-6 2-Amino-6-chloropurine-3',5'-di-O-acetyl-2'-deoxyriboside is an analogue of purine nucleoside.
2-Amino-6-chloropurine-9-(2’-O-propargyl)riboside V55342 2-Amino-6-chloropurine-9-(2'-O-propargyl)riboside 2095417-35-7 2-Amino-6-chloropurine-9-(2'-O-propargyl)riboside is an analogue of purine nucleoside.
2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside V55515 2-Amino-6-chloropurine-9-beta-D-(2'-deoxy)riboside 120595-72-4 2-Amino-6-chloropurine-9-beta-D-(2'-deoxy)riboside is an analogue of purine nucleoside.
2-Amino-6-chloropurine-9-beta-D-(2’-deoxy-2’-fluoro)-arabinoriboside V55476 2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside 144924-88-9 2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside is an analogue of purine nucleoside.
2-Amino-6-chloropurine-9-beta-D-(2’-deoxy-3’,5’-di-O-(p-toluoyl))riboside V55949 2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-3',5'-di-O-(p-toluoyl))riboside 35095-93-3 2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-3',5'-di-O-(p-toluoyl))riboside is an analogue of purine nucleoside.
2-Amino-6-chloropurine-9-beta-d-(2'-deoxy-3',5'-di-o-benzoyl-2'-fluoro)arabinoriboside V55684 2-Amino-6-chloropurine-9-beta-d-(2'-deoxy-3',5'-di-o-benzoyl-2'-fluoro)arabinoriboside 118373-61-8 2-Amino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside is an analogue of purine nucleoside.
2-Amino-6-meThythio-9-(β-D-ribofuranosyl)-9H-purine V75767 2-Amino-6-meThythio-9-(β-D-ribofuranosyl)-9H-purine 4914-73-2 2-Amino-6-meThythio-9-(β-D-ribofuranosyl)-9H-purine is an analogue of purine nucleoside.
2-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(beta-D-xylo furanosyl)purine V75572 2-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(beta-D-xylo furanosyl)purine 2389988-30-9 2-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(beta-D-xylo furanosyl)purine (G159-82) PTPD-2 Confidential is an analogue of purine nucleoside.
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine V56015 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine 2389988-75-2 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is an analogue of purine nucleoside.
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine V55656 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine 2389988-53-6 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is an analogue of purine nucleoside.
2-Amino-8-aza-7-deaza-7-iodoguanosine V55968 2-Amino-8-aza-7-deaza-7-iodoguanosine 1997362-13-6 2-Amino-8-aza-7-deaza-7-iodoguanosine is an analogue of purine nucleoside.
2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine V75933 2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine 109304-04-3 2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an analogue of purine nucleoside.
2-Amino-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine V75772 2-Amino-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine 690269-87-5 2-Ami no-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine is an analogue of purine nucleoside.
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