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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside V55539 2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside 1612192-01-4 2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside is an analogue of purine nucleoside.
2-Chloro-6-methoxypurine riboside V51313 2-Chloro-6-methoxypurine riboside 15465-92-6 2-Chloro-6-methoxypurine riboside is an analog of hypoxanthine.
2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine V75534 2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine 758705-70-3 2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine is an analogue of purine nucleoside.
2-Chloro-9-(beta-D-ribofuranosyl)purine V55311 2-Chloro-9-(beta-D-ribofuranosyl)purine 5466-11-5 2-Chloro-9-(beta-D-ribofuranosyl)purine is an analogue of purine nucleoside.
2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine V75702 2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine 1260177-41-0 2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine is an analogue of purine nucleoside.
2-Chloro-N6,N6-dimethyladenosine V55972 2-Chloro-N6,N6-dimethyladenosine 13406-53-6 2-Chloro-N6,N6-dimethyladenosine is an analogue of purine nucleoside.
2-Chloro-N6-(2-hydroxyethyl)adenosine V75729 2-Chloro-N6-(2-hydroxyethyl)adenosine 948298-76-8 2-Chloro-N6-(2-hydroxyethyl)adenosine is an analogue of purine nucleoside.
2-Chloro-N6-cyclopentyl 2’-deoxy- adenosine V55339 2-Chloro-N6-cyclopentyl 2'-deoxy-adenosine 215108-39-7 2-Chloro-N6-cyclopentyl 2'-deoxy-adenosine is an analogue of purine nucleoside.
2-Chloro-N6-cyclopentyl-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine V55844 2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine 2216764-33-7 2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine is an analogue of purine nucleoside.
2-Chloro-N6-iso-pentenyladenosine V75584 2-Chloro-N6-iso-pentenyladenosine 65400-39-7 2-Chloro-N6-iso-pentenyladenosine is an analogue of purine nucleoside.
2-Chloro-N6-isopropyladenosine V55782 2-Chloro-N6-isopropyladenosine 23541-30-2 2-Chloro-N6-isopropyladenosine is an analogue of purine nucleoside.
2-Chloro-N6-methyl-2’-deoxyadenosine V55895 2-Chloro-N6-methyl-2'-deoxyadenosine 146196-08-9 2-Chloro-N6-methyl-2'-deoxyadenosine is an analogue of purine nucleoside.
2-Chloro-N6-methyladenosine V55580 2-Chloro-N6-methyladenosine 13406-50-3 2-Chloro-N6-methyladenosine is an analogue of purine nucleoside.
2-Chloroinosine ((2R,3R,4S,5R)-2-(2-氯-6-羟基-9H-嘌呤-9-基)-5-(羟甲基)四氢呋喃-3,4-二醇) V55344 2-Chloroinosine ((2R,3R,4S,5R)-2-(2-chloro-6-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol) 13276-43-2 2-Chloroinosine is an analogue of purine nucleoside.
2-Cyanoadenosine V55355 2-Cyanoadenosine 79936-11-1 2-Cyanoadenosine is an analogue of purine nucleoside.
2-Cyanomethylthioadenosine V55549 2-Cyanomethylthioadenosine 2095417-67-5 2-Cyanomethylthioadenosine is an adenine nucleoside analog.
2-Deoxy-2’-deoxy-5’-(4,4’-dimethoxytrityl)uridine V55637 2-Deoxy-2'-deoxy-5'-(4,4'-dimethoxytrityl)uridine 151503-26-3 2-Deoxy-2'-deoxy-5'-(4,4'-dimethoxytrityl)uridine is an analogue of purine nucleoside.
2-Deoxy-2’-fluoroisocytidine V55412 2-Deoxy-2'-fluoroisocytidine 1668560-65-3 2-Deoxy-2'-fluoroisocytidine is an analogue of purine nucleoside.
2-Deoxyuridine V75585 2-Deoxyuridine 21052-20-0 2-Deoxyuridine is an analogue of purine nucleoside.
2-Hydrazinyl-adenosine V75691 2-Hydrazinyl-adenosine 15763-11-8 2-Hydrazinyl-adenosine is an analogue of purine nucleoside.
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