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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine V75570 2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine 899827-82-8 2-Hydroxy-2'-de oxy-2'-fluoro-beta-D-arabino adenosine is an analogue of purine nucleoside.
2-Iodoadenosine (6-氨基-2-碘-9-(β-D-吡喃核糖基)嘌呤) V55262 2-Iodoadenosine (6-amino-2-iodo-9-(β-D-ribopyranosyl)purine) 35109-88-7 2-Iodoadenosine is an adenine nucleoside analog.
2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine V75755 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine 1093278-52-4 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine is an analogue of purine nucleoside.
2-Methoxy-2’-deoxyadenosine V55927 2-Methoxy-2'-deoxyadenosine 24757-70-8 2-Methoxy-2'-deoxyadenosine is an adenine nucleoside analog.
2-Methoxy-9-β-D-ribofuranosyl-9H-purine V75931 2-Methoxy-9-β-D-ribofuranosyl-9H-purine 39638-84-1 2-Methoxy-9-β-D-ribofuranosyl-9H-purine is an analogue of purine nucleoside.
2-Methyl-2’-deoxyadenosine V55419 2-Methyl-2'-deoxyadenosine 110952-90-4 2-Methyl-2'-deoxyadenosine is an analogue of purine nucleoside.
2-Methyladenosine V75738 2-Methyladenosine 16526-56-0 2-Methyladenosine is an adenine nucleoside analogue.
2-Methylamino-N6-methyladenosine V55313 2-Methylamino-N6-methyladenosine 28360-91-0 2-Methylamino-N6-methyladenosine is an analogue of purine nucleoside.
2-Methylthioadenosine V55528 2-Methylthioadenosine 4105-39-9 2-Methylthioadenosine is an analogue of purine nucleoside.
2-O-Benzoyl-3-Ot-butyldiphenylsilyl-L-threonolactone V75620 2-O-Benzoyl-3-Ot-butyldiphenylsilyl-L-threonolactone 1446785-28-9 2-O-Benzoyl-3-Ot-butyldiphenylsilyl-L-threono lactone is an analogue of purine nucleoside.
2-Thiocytidine (2-硫代胞苷) V53312 2-Thiocytidine 13239-97-9 2-Thiocytidine is an analogue of purine nucleoside.
2-Thiopseudouridine V55910 2-Thiopseudouridine 59464-18-5 2-Thiopseudouridine is an analogue of purine nucleoside.
2-Thiothymidine (2-硫代-2'-脱氧胸苷) V55516 2-Thiothymidine (2-thio-2'-deoxythymidine) 28585-51-5 2-Thiothymidine is an analogue of purine nucleoside.
2-Trifluoromethyl adenosine V55318 2-Trifluoromethyl adenosine 4627-40-1 2-Trifluoromethyl adenosine is an analogue of purine nucleoside.
2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine V75518 2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine 124137-35-5 2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is an analogue of purine nucleoside.
3',4-Dideoxyuridine V75753 3',4-Dideoxyuridine 2095417-04-0 3',4-Dideoxyuridine is an analogue of purine nucleoside.
3′,5′-Bis-O-(triphenylmethyl)uridine V55805 3′,5′-Bis-O-(triphenylmethyl)uridine 4710-75-2 3′,5′-Bis-O-(triphenylmethyl)uridine is a uridine analog.
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine V55802 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine 136675-87-1 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine is an analogue of purine nucleoside.
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabino-6-azidouridine V55787 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabino-6-azidouridine 1013470-68-2 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabino-6-azidouridine is an analogue of purine nucleoside.
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinouridine V75561 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinouridine 128496-10-6 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinouridine is an analogue of purine nucleoside.
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