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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
1,4-Anhydro-2,3-di-O-isopropylidene-4-thio-D-ribitol V55628 1,4-Anhydro-2,3-di-O-isopropylidene-4-thio-D-ribitol 596103-06-9 1,4-Anhydro-2,3-di-O-isopropylidene-4-thio-D-ribitol is an analogue of purine nucleoside.
1,4-Anhydro-2,3-O-isopropylidene-5-O-t-butyldiphenylsilyl-4-thio-D-ribitol V55819 1,4-Anhydro-2,3-O-isopropylidene-5-Ot-butyldiphenylsilyl-4-thio-D-ribitol 1320269-77-9 1,4-Anhydro-2,3-O-isopropylidene-5-Ot-butyldiphenylsilyl-4-thio-D-ribitol is an analogue of purine nucleoside.
1,9-Dihydro-9-β-D-xylofuranosyl-6H-purin-6-one V75939 1,9-Dihydro-9-β-D-xylofuranosyl-6H-purin-6-one 10517-16-5 1,9-Dihydro-9-β-D-xylofuranosyl-6H-purin-6-one is an analogue of purine nucleoside.
1,N6-Etheno-9-(β-D-xylofuranosyl)adenosine V75530 1,N6-Etheno-9-(β-D-xylofuranosyl)adenosine 2095417-39-1 1,N6-Etheno-9-(β-D-xylofuranosyl)adenosine is an analogue of purine nucleoside.
1,N6-Etheno-ara-adenosine V75740 1,N6-Etheno-ara-adenosine 2095417-09-5 1,N6-Etheno-ara-adenosine is an analogue of purine nucleoside.
1,N6-Ethenoadenosine V75685 1,N6-Ethenoadenosine 39007-51-7 1,N6-Ethenoadenosine is an analogue of purine nucleoside.
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite V55518 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-bD-arabinofuranosyl)thymine 3'-CE phosphoramidite 208193-48-0 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-bD-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine nucleoside analogue.
1-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione V75957 1-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione 23643-36-9 1-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione is a uridine nucleoside analogue.
1-(2,3,5-Tri-O-benzoyl-2-C-β-methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one V75964 1-(2,3,5-Tri-O-benzoyl-2-C-β-methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one 2072145-38-9 1-(2,3,5-Tri-O-benzoyl-2-C-β-methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a nitropyridine nucleoside analog things.
1-(2,3-Dideoxy-β-D-erythro-hexopyranosyl)cytosine V75560 1-(2,3-Dideoxy-β-D-erythro-hexopyranosyl)cytosine 136020-18-3 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine is an analogue of purine nucleoside.
1-(2-C-β-Methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one V75923 1-(2-C-β-Methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one 2072145-17-4 1-(2-C-β-Methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a nitropyridine nucleoside analog.
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil (1-(2-脱氧-2-氟-beta-D-阿拉伯呋喃基)尿嘧啶) V55293 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil 69123-94-0 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is an analogue of purine nucleoside.
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione V75936 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione 83546-42-3 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue.
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4(1H)-pyrimidinone V75926 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4(1H)-pyrimidinone 37109-98-1 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4(1H)-pyrimidinone is an analogue of purine nucleoside.
1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine V75906 1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine 16053-52-4 1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine is a thymidine analogue.
1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine V55815 1-(3'-O-[4,4'-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine 325683-89-4 1-(3'-O-[4,4'-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine is an analogue of purine nucleoside.
1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)uridine V56003 1-(3'-O-[4,4'-Dimethoxytrityl]-alpha-L-threofuranosyl)uridine 325683-90-7 1-(3'-O-[4,4'-dimethoxytrityl]-alpha-L-threofuranosyl)uridine is an analogue of purine nucleoside.
1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine V55438 1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine 73971-79-6 1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine is an analogue of purine nucleoside.
1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione V75943 1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione 129885-95-6 1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione is an analogue of purine nucleoside.
1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine V75758 1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine 66503-47-7 1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine is an analogue of purine nucleoside.
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