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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine V55497 3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine 29706-84-1 3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine V55422 3'-Azido-3'-deoxy-5-fluoro-beta-L-cytidine 2095417-76-6 3'-Azido-3'-deoxy-5-fluoro-beta-L-cytidine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine V56010 3'-Azido-3'-deoxy-5-fluoro-beta-L-uridine 2095417-40-4 3'-Azido-3'-deoxy-5-fluoro-beta-L-uridine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-5-fluorouridine V55796 3'-Azido-3'-deoxy-5-fluorouridine 307520-05-4 3'-Azido-3'-deoxy-5-fluorouridine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-5-iodouridine V55881 3'-Azido-3'-deoxy-5-iodouridine 2072145-33-4 3'-Azido-3'-deoxy-5-iodouridine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-5-methoxyuridine V55984 3'-Azido-3'-deoxy-5-methoxyuridine 2095417-70-0 3'-Azido-3'-deoxy-5-methoxyuridine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-5-methyl-beta-L-cytidine V55938 3'-Azido-3'-deoxy-5-methyl-beta-L-cytidine 2095417-52-8 3'-Azido-3'-deoxy-5-methyl-beta-L-cytidine is an analogue of purine nucleoside.
3'-Azido-3'-deoxy-5-methyl-beta-L-uridine V75676 3'-Azido-3'-deoxy-5-methyl-beta-L-uridine 2095417-10-8 3'-Azido-3'-deoxy-5-methyl-beta-L-uridine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-5-methyluridine V55799 3'-Azido-3'-deoxy-5-methyluridine 215176-58-2 3'-Azido-3'-deoxy-5-methyluridine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-5-trifluoromethyluridine V55573 3'-Azido-3'-deoxy-5-trifluoromethyluridine 2095417-62-0 3'-Azido-3'-deoxy-5-trifluoromethyluridine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-beta-L-adenosine V55485 3'-Azido-3'-deoxy-beta-L-adenosine 216976-76-0 3'-Azido-3'-deoxy-beta-L-adenosine is an analogue of purine nucleoside.
3'-Azido-3'-deoxy-beta-L-cytidine V75654 3'-Azido-3'-deoxy-beta-L-cytidine 2095417-59-5 3'-Azido-3'-deoxy-beta-L-cytidine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-N6,N6-dimethyladenosine V55824 3'-Azido-3'-deoxy-N6,N6-dimethyladenosine 384334-64-9 3'-Azido-3'-deoxy-N6,N6-dimethyladenosine is an analogue of purine nucleoside.
3’-Azido-3’-deoxy-N6-methyladenosine V55609 3'-Azido-3'-deoxy-N6-methyladenosine 889126-08-3 3'-Azido-3'-deoxy-N6-methyladenosine is an analogue of purine nucleoside.
3'-Azido-3'-deoxyadenosine V55472 3'-Azido-3'-deoxyadenosine 58699-62-0 3'-Azido-3'-deoxyadenosine is an analogue of purine nucleoside.
3'-Azido-3'-deoxycytidine V75596 3'-Azido-3'-deoxycytidine 70580-87-9 3'-Azido-3'-deoxycytidine is an analogue of purine nucleoside.
3'-Azido-3'-deoxyguanosine V35155 3'-Azido-3'-deoxyguanosine 98870-11-2 Urolignoside is an antioxidant with free radical scavenging activity.
3’-Azido-3’-deoxyinosine V55669 3'-Azido-3'-deoxyinosine 946497-27-4 3'-Azido-3'-deoxyinosine is an analogue of purine nucleoside.
3’-Azido-3’-deoxyuridine V55997 3'-Azido-3'-deoxyuridine 70580-88-0 3'-Azido-3'-deoxyuridine is an analogue of purine nucleoside.
3’-Azido-N6-benzoyl-3’-deoxyadenosine V55348 3'-Azido-N6-benzoyl-3'-deoxyadenosine 103597-10-0 3'-Azido-N6-benzoyl-3'-deoxyadenosine is an analogue of purine nucleoside.
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