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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
3’-beta-Azido-2’,3’-dideoxy-5’-O-(4-methoxy-trityl)uridine V55945 3'-beta-Azido-2',3'-dideoxy-5'-O-(4-methoxy-trityl)uridine 2072145-36-7 3'-beta-Azido-2',3'-dideoxy-5'-O-(4-methoxy-trityl)uridine is an analogue of purine nucleoside.
3'-beta-Azido-2',3'-dideoxyuridine V75703 3'-beta-Azido-2',3'-dideoxyuridine 101039-96-7 3'-beta-Azido-2',3'-dideoxyuridine is an analogue of purine nucleoside.
3’-beta-C-Methyl-5-methyluridine V55474 3'-beta-C-Methyl-5-methyluridine 934002-35-4 3'-beta-C-Methyl-5-methyluridine is a thymidine analog.
3’-beta-C-Methyl-N6-methyladenosine V55490 3'-beta-C-Methyl-N6-methyladenosine 565450-84-2 3'-beta-C-Methyl-N6-methyladenosine is an adenine nucleoside analog.
3’-beta-C-Methyladenosine V55686 3'-beta-C-Methyladenosine 15397-13-4 3′-β-C-Methyladenosine is an adenine nucleoside analog.
3’-beta-C-Methylcytidine V56023 3'-beta-C-Methylcytidine 20724-72-5 3'-beta-C-Methylcytidine is a cytosine nucleoside analog.
3'-beta-C-Methyluridine V75583 3'-beta-C-Methyluridine 80541-15-7 3'-beta-C-Methyluridine is a uridine analog.
3′-Bromo-3′-deoxythymidine V75722 3′-Bromo-3′-deoxythymidine 99785-51-0 3′-Bromo-3′-deoxythymidine is an analogue of purine nucleoside.
3'-C-Methylguanosine V51789 3'-C-Methylguanosine 115303-89-4 3'-C-Methylguanosine is an analog of guanosine.
3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine V55651 3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine 34627-62-8 3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is an analogue of purine nucleoside.
3′-Chloro-3′-deoxythymidine V55818 3′-Chloro-3′-deoxythymidine 25526-94-7 3′-Chloro-3′-deoxythymidine is an analogue of purine nucleoside.
3'-dC(Bz)-2'-phosphor amidite (N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxycytidine 2' -[2-Cyanoethyldiisopropylaminophosphite]) V75680 3'-dC(Bz)-2'-phosphor amidite (N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxycytidine 2' -[2-Cyanoethyldiisopropylaminophosphite]) 157327-96-3 3'-dC(Bz)-2'-phosphor amidite is an analogue of purine nucleoside.
3’-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)-L-arabinofuranose V55292 3'-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)-L-arabinofuranose 2072145-19-6 3'-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)-L-arabinofuranose is an analogue of purine nucleoside.
3’-Deoxy-2’,5’-di-O-acetyl-8-hydroxyguanosine V55655 3'-Deoxy-2',5'-di-O-acetyl-8-hydroxyguanosine 2389988-72-9 3'-Deoxy-2',5'-di-O-acetyl-8-hydroxyguanosine is an analogue of purine nucleoside.
3’-Deoxy-2’-thiouridine V55598 3'-Deoxy-2'-thiouridine 455951-69-6 3'-Deoxy-2'-thiouridine is an analogue of purine nucleoside.
3'-Deoxy-3',5-difluorocytidine V75587 3'-Deoxy-3',5-difluorocytidine 661470-65-1 3'-Deoxy-3',5-difluorocytidine is an analogue of purine nucleoside.
3’-Deoxy-3’-azido-isocytidine V55588 3'-Deoxy-3'-azido-isocytidine 2095417-77-7 3'-Deoxy-3'-azido-isocytidine is an analogue of purine nucleoside.
3’-Deoxy-3’-flluoro-3-deazauridine V55978 3'-Deoxy-3'-flluoro-3-deazauridine 2072145-34-5 3'-Deoxy-3'-flluoro-3-deazauridine is an analogue of purine nucleoside.
3’-Deoxy-3’-fluoro-2-thiouridine V55928 3'-Deoxy-3'-fluoro-2-thiouridine 439579-24-5 3'-Deoxy-3'-fluoro-2-thiouridine is an analogue of purine nucleoside.
3'-Deoxy-3'-fluoro-5-fluorouridine V75677 3'-Deoxy-3'-fluoro-5-fluorouridine 112668-56-1 3'-Deoxy-3'-fluoro-5-fluorouridine is an analogue of purine nucleoside.
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