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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
3’-Deoxy-3’-fluoro-5-methoxyluridine V55680 3'-Deoxy-3'-fluoro-5-methoxyluridine 2072145-76-5 3'-Deoxy-3'-fluoro-5-methoxyluridine is an analogue of purine nucleoside.
3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine V55921 3'-Deoxy-3'-fluoro-5-methyl-xylo-uridine 917110-29-3 3'-Deoxy-3'-fluoro-5-methyl-xylo-uridine is an analogue of purine nucleoside.
3'-Deoxy-3'-fluoro-5-methylcytidine V75650 3'-Deoxy-3'-fluoro-5-methylcytidine 847650-07-1 3'-Deoxy-3'-fluoro-5-methylcytidine is an analogue of purine nucleoside.
3’-Deoxy-3’-fluoro-5-methyluridine V55645 3'-Deoxy-3'-fluoro-5-methyluridine 125217-37-0 3'-Deoxy-3'-fluoro-5-methyluridine is an analogue of purine nucleoside.
3’-Deoxy-3’-fluoro-5-trifluoromethyluridine V55502 3'-Deoxy-3'-fluoro-5-trifluoromethyluridine 439579-21-2 3'-Deoxy-3'-fluoro-5-trifluoromethyluridine is an analogue of purine nucleoside.
3'-Deoxy-3'-fluoro-6-azauridine V75578 3'-Deoxy-3'-fluoro-6-azauridine 439579-23-4 3'-Deoxy-3'-fluoro-6-azauridine is an analogue of purine nucleoside.
3’-Deoxy-3’-fluoro-beta-D-xylo-inosine V55911 3'-Deoxy-3'-fluoro-beta-D-xylo-inosine 171667-46-2 3'-Deoxy-3'-fluoro-beta-D-xylo-inosine is an analogue of purine nucleoside.
3’-Deoxy-3’-fluoro-N6,N6-dimethyladenosine V55433 3'-Deoxy-3'-fluoro-N6,N6-dimethyladenosine 122654-28-8 3'-Deoxy-3'-fluoro-N6,N6-dimethyladenosine is an analogue of purine nucleoside.
3'-Deoxy-3'-fluoro-N6-methyladenosine V75715 3'-Deoxy-3'-fluoro-N6-methyladenosine 122654-27-7 3'-Deoxy-3'-fluoro-N6-methyladenosine is an analogue of purine nucleoside.
3'-Deoxy-3'-fluoro-xyloadenosine V75717 3'-Deoxy-3'-fluoro-xyloadenosine 20535-16-4 3'-Deoxy-3'-fluoro-xyloadenosine is an analogue of purine nucleoside.
3’-Deoxy-3’-fluoro-xylocytidine V55470 3'-Deoxy-3'-fluoro-xylocytidine 26563-01-9 3'-Deoxy-3'-fluoro-xylocytidine is an analogue of purine nucleoside.
3'-Deoxy-3'-fluoro-xyloguanosine V75624 3'-Deoxy-3'-fluoro-xyloguanosine 125291-15-8 3'-Deoxy-3'-fluoro-xyloguanosine is an analogue of purine nucleoside.
3'-Deoxy-3'-fluoroadenosine V75674 3'-Deoxy-3'-fluoroadenosine 75059-22-2 3'-Deoxy-3'-fluoroadenosine is an analogue of purine nucleoside.
3′-Deoxy-3′-fluorocytidine V56020 3′-Deoxy-3′-fluorocytidine 123402-20-0 3′-Deoxy-3′-fluorocytidine is an analogue of purine nucleoside.
3’-Deoxy-3’-fluoroinosine V55964 3'-Deoxy-3'-fluoroinosine 117517-20-1 3'-Deoxy-3'-fluoroinosine is an analogue of purine nucleoside.
3′-Deoxy-3′-fluorouridine V56005 3′-Deoxy-3′-fluorouridine 57944-13-5 3′-Deoxy-3′-fluorouridine is an analogue of purine nucleoside.
3′-Deoxy-3′-iodothymidine V55668 3′-Deoxy-3′-iodothymidine 14260-82-3 3′-Deoxy-3′-iodothymidine is an analogue of purine nucleoside.
3′-Deoxy-3′-methylcytidine V55307 3′-Deoxy-3′-methylcytidine 444020-09-1 3′-Deoxy-3′-methylcytidine is an analogue of purine nucleoside.
3'-Deoxy-3'-α-C-methyl-5-fluorouridine V75675 3'-Deoxy-3'-α-C-methyl-5-fluorouridine 37731-67-2 3'-Deoxy-3'-α-C-methyl-5-fluorouridine is an analogue of purine nucleoside.
3'-Deoxy-3'-α-C-methyl-5-methyluridine V75741 3'-Deoxy-3'-α-C-methyl-5-methyluridine 847650-50-4 3'-Deoxy-3'-α-C-methyl-5-methyluridine is an analogue of purine nucleoside.
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