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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
3’-O-Me-C(Bz)-2’-phosphoramidite V55574 3'-O-Me-C(Bz)-2'-phosphoramidite 179479-03-9 3'-O-Me-C(Bz)-2'-phosphoramidite is an analogue of purine nucleoside.
3’-O-Me-G(iBu)-2’-phosphoramidite V55303 3'-O-Me-G(iBu)-2'-phosphoramidite 179479-04-0 3'-O-Me-G(iBu)-2'-phosphoramidite is a guanine nucleoside analog.
3’-O-Methyl inosine V55570 3'-O-Methyl inosine 75479-64-0 3'-O-Methyl inosine is an analogue of purine nucleoside.
3'-O-Methyl-2'-O-acetyl-5'-O-benzoyluridine V75746 3'-O-Methyl-2'-O-acetyl-5'-O-benzoyluridine 2072145-71-0 3'-O-Methyl-2'-O-acetyl-5'-O-benzoyluridine is an analogue of purine nucleoside.
3’-O-Methyl-4-deoxy uridine V55565 3'-O-Methyl-4-deoxyuridine 2095417-12-0 3'-O-Methyl-4-deoxy uridine is an analogue of purine nucleoside.
3’-O-Methyl-5-methyluridine V55467 3'-O-Methyl-5-methyluridine 2305415-87-4 3'-O-Methyl-5-methyluridine is a thymidine analog.
3′-O-Methylcytidine V55280 3′-O-Methylcytidine 20594-00-7 3′-O-Methylcytidine is a cytosine nucleoside analog.
3’-O-Methyluridine (4-[1-[(2-Methylphenyl)methyl]benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine) V55890 3'-O-Methyluridine (4-[1-[(2-Methylphenyl)methyl]benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine) 6038-59-1 3'-O-Methyluridine is an analogue of purine nucleoside.
3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite V55827 3'-O-MOE-5Me-C(Bz)-2'-phosphoramidite 1098233-10-3 3'-O-MOE-5Me-C(Bz)-2'-phosphoramidite is an analogue of purine nucleoside.
3’-O-MOE-5MeU-2’-phosphoramidite V55792 3'-O-MOE-5MeU-2'-phosphoramidite 256223-93-5 3'-O-MOE-5MeU-2'-phosphoramidite is an analogue of purine nucleoside.
3’-O-MOE-A(Bz)-2’-CED-phosphoramidite V55685 3'-O-MOE-A(Bz)-2'-CED-phosphoramidite 256224-01-8 3'-O-MOE-A(Bz)-2'-CED-phosphoramidite is an analogue of purine nucleoside.
3’-O-MOE-G(iBu)-2’-phosphoramidite V55809 3'-O-MOE-G(iBu)-2'-phosphoramidite 256224-06-3 3'-O-MOE-G(iBu)-2'-phosphoramidite is a guanine nucleoside analog.
3’-O-MOE-U-2’-phosphoramidite V55520 3'-O-MOE-U-2'-phosphoramidite 1452849-90-9 3'-O-MOE-U-2'-phosphoramidite is an analogue of purine nucleoside.
3’-O-Propargyladenosine V55961 3'-O-Propargyladenosine 2305416-10-6 3'-O-Propargyladenosine is an adenine nucleoside analog.
3’-O-t-Bulyldimethylsilylthymidine (3'-O-[叔丁基(二甲基)硅基]胸苷) V55388 3'-Ot-Bulyldimethylsilylthymidine (3'-O-[tert-butyl(dimethyl)silyl]thymidine) 40733-27-5 3'-Ot-Bulyldimethylsilylthymidine is an analogue of purine nucleoside.
3’-O-t-Butyldimethylsilyladenosine V55505 3'-Ot-Butyldimethylsilyladenosine 69504-14-9 3'-Ot-Butyldimethylsilyladenosine is an adenine nucleoside analogue.
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine V55508 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine 89947-86-4 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is an analogue of purine nucleoside.
3'-β-Amino-2',3'-dideoxy-5'-O-methoxy trityluridine V75515 3'-β-Amino-2',3'-dideoxy-5'-O-methoxy trityluridine 2072145-31-2 3'-β-Amino-2',3'-dideoxy-5'-O-methoxy trityluridine is an analogue of purine nucleoside.
3'-β-Amino-2',3'-dideoxy-5'-O-trityl-5-methyl uridine V75573 3'-β-Amino-2',3'-dideoxy-5'-O-trityl-5-methyl uridine 204688-08-4 3'-β-Amino-2',3'-dideoxy-5'-O-trityl-5-methyl uridine is an analogue of purine nucleoside.
3'-β-C-Ethynyl-5-methyl uridine V75539 3'-β-C-Ethynyl-5-methyl uridine 180300-52-1 3'-β-C-Ethynyl-5-methyl uridine is a thymidine analog.
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