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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
3'-β-C-Ethynyl-N6,N6-dimethyladenosine V75706 3'-β-C-Ethynyl-N6,N6-dimethyladenosine 565450-82-0 3'-β-C-Ethynyl-N6,N6-dimethyladenosine is an adenine nucleoside analog.
3'-β-C-Ethynyladenosine V75934 3'-β-C-Ethynyladenosine 180300-54-3 3'-β-C-Ethynyladenosine is an adenine nucleoside analog.
3’-β-C-Ethynylguanosine V51793 3’-β-C-Ethynylguanosine 180300-56-5 3’-β-C-Ethynylguanosine is an analog of guanosine.
3'-β-C-Ethynyluridine V75911 3'-β-C-Ethynyluridine 180300-49-6 3'-β-C-Ethynyluridine is a uridine analog.
3,4-Dihydro-3-oxo-4-β-D-ribofuranosyl-2-pyrazinecarboxamide V75555 3,4-Dihydro-3-oxo-4-β-D-ribofuranosyl-2-pyrazinecarboxamide 356782-84-8 3,4-Dihydro-3-oxo-4-β-D-ribofuranosyl-2-pyrazinecarboxamide is an analogue of purine nucleoside.
3,5-Bis-O-(2,4-dichlorobenzyl)adenosine V55794 3,5-Bis-O-(2,4-dichlorobenzyl)adenosine 2095417-71-1 3,5-Bis-O-(2,4-dichlorobenzyl)adenosine is an adenine nucleoside analogue.
3,5-Bis-O-(2,4-dichlorobenzyl)guanosine V55386 3,5-Bis-O-(2,4-dichlorobenzyl)guanosine 2095417-36-8 3,5-Bis-O-(2,4-dichlorobenzyl)guanosine is a guanine nucleoside analog.
3,5-Bis-O-(4-methylbenzoyl)-2-C-methyl-D-ribonic acid gama-lactone V55495 3,5-Bis-O-(4-methylbenzoyl)-2-C-methyl-D-ribonic acid gama-lactone 25137-77-3 3,5-Bis-O-(4-methylbenzoyl)-2-C-methyl-D-ribonic acid gama-lactone is an analogue of purine nucleoside.
3,5-Di-O-benzoyl-2-deoxy-2-fluoro-5-trifluoromethyl-arabinouridine V55696 3,5-Di-O-benzoyl-2-deoxy-2-fluoro-5-trifluoromethyl-arabinouridine 117311-99-6 3,5-Di-O-benzoyl-2-deoxy-2-fluoro-5-trifluoromethyl-arabinouridine is an analogue of purine nucleoside.
3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside V75545 3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside 91713-46-1 3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside is an analogue of purine nucleoside.
3-(2-Pyridinylmethyl)uridine V55687 3-(2-Pyridinylmethyl)uridine 1427676-15-0 N3-[(Pyrid-2-yl)methyl]uridine is a uridine analog.
3-Deaza-4’-C-methyluridine V55627 3-Deaza-4'-C-methyluridine 2305415-96-5 3-Deaza-4'-C-methyluridine, 4-Hydroxy-1-β-D-(4-C-methylribofuranosyl)-2(1H)-pyridinone is an analogue of purine nucleoside.
3-Deazauridine (NSC 126849) V52851 3-Deazauridine (NSC 126849) 23205-42-7 3-Deazauridine (NSC 126849) is a uridine analog.
3-Deoxy-1,2-O-isopropylidene-5-p-toluoyl-a-D-glycero-pent-3-enofuranose V55697 3-Deoxy-1,2-O-isopropylidene-5-p-toluoyl-aD-glycero-pent-3-enofuranose 75096-63-8 3-Deoxy-1,2-O-isopropylidene-5-p-toluoyl-aD-glycero-pent-3-enofuranose is an analogue of purine nucleoside.
3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose V75963 3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose 4613-62-1 3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose is an analogue of purine nucleoside.
3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione V75548 3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione 81691-06-7 3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione is an analogue of purine nucleoside.
3-O-(4-Methoxybenzyl)-4-C-hydroxymethyl-1,2-O-isopropylidine-alpha-D-ribofuranose V75616 3-O-(4-Methoxybenzyl)-4-C-hydroxymethyl-1,2-O-isopropylidine-alpha-D-ribofuranose 225233-47-6 3-O-(4-Methoxybenzyl)-4-C-hydroxymethyl-1,2-O-isopropylidine-alpha-D-ribofuranose is an analogue of purine nucleoside.
3-O-Benzoyl-1,2: 5,6-bis(di-O-isopropylidene)-alpha-D-galactofuranose V55864 3-O-Benzoyl-1,2: 5,6-bis(di-O-isopropylidene)-alpha-D-galactofuranose 29474-73-5 3-O-Benzoyl-1,2: 5,6-bis(di-O-isopropylidene)-alpha-D-galactofuranose is an analogue of purine nucleoside.
3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one V75946 3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one 1058167-74-0 3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one is an analogue of purine nucleoside.
4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine V55660 4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine 1365255-75-9 4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine is an analogue of purine nucleoside.
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