Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V55337 | 4′,5′-Didehydro-2′,5′-dideoxyuridine | 58096-66-5 | 4′,5′-Didehydro-2′,5′-dideoxyuridine is an analogue of purine nucleoside. |
|
V55578 | 4',5'-Didehydro-2'-O-(2-methoxyethyl)-5-methyluridine | 2095417-31-3 | 4',5'-Didehydro-2'-O-(2-methoxyethyl)-5-methyluridine is an analogue of purine nucleoside. |
|
V55435 | 4',5'-Didehydro-2'-O-(2-methoxyethyl)uridine | 2095417-78-8 | 4',5'-Didehydro-2'-O-(2-methoxyethyl)uridine is an analogue of purine nucleoside. |
|
V55538 | 4',5'-Didehydro-2'-O-methyl-5-methyluridine | 2095417-11-9 | 4',5'-Didehydro-2'-O-methyl-5-methyluridine is an analogue of purine nucleoside. |
|
V55383 | 4',5'-Didehydro-5'-deoxythymidine | 28034-72-2 | 4',5'-Didehydro-5'-deoxy thymidine is an analogue of purine nucleoside. |
|
V75696 | 4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine | 1848223-48-2 | 4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine is an analogue of purine nucleoside. |
|
V55513 | 4′,5′-Didehydro-5′-deoxy-5-methyluridine | 1446748-33-9 | 4′,5′-Didehydro-5′-deoxy-5-methyluridine is an analogue of purine nucleoside. |
|
V55695 | 4′,5′-Didehydro-5′-deoxyadenosine | 20535-04-0 | 4′,5′-Didehydro-5′-deoxyadenosine is an analogue of purine nucleoside. |
|
V53347 | 4',5'-Didehydro-5'-deoxyuridine (1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)uracil) | 14365-63-0 | 4',5'-Didehydro-5'-deoxyuridine is an analogue of purine nucleoside. |
|
V75694 | 4'-alpha-C-Allyl-2',3'-bis(Ot-butyldimethylsilyl) uridine | 512184-18-8 | 4'-alpha-C-Allyl-2',3'-bis(Ot-butyldimethylsilyl) uridine is a uridine analogue. |
|
V55601 | 4'-Azido-2'-deoxy-2'-fluoro-beta-D-arabinouridine | 173379-73-2 | 4'-Azido-2'-deoxy-2'-fluoro-beta-D-arabinouridine is a uridine analog. |
|
V55665 | 4'-Azido-3'-O-benzoyl-5'-O-(m-chlorobenzoyl)-2'-deoxy-2'-fluoro-beta-D-arabinouridine | 1333126-30-9 | 4'-Azido-3'-O-benzoyl-5'-O-(m-chlorobenzoyl)-2'-deoxy-2'-fluoro-beta-D-arabinouridine is an analogue of purine nucleoside. |
|
V55793 | 4′-C-2-Propen-1-yluridine | 66723-28-2 | 4′-C-2-Propen-1-yluridine is a uridine analog. |
|
V53352 | 4'-C-Azidouridine (4'-Azidouridine) | 139442-01-6 | 4'-C-azidouridine (4'-Azidouridine) is a uridine analog. |
|
V55316 | 4'-C-Methyl-2-thiouridine | 2305415-74-9 | 4'-C-Methyl-2-thiouridine is an analogue of purine nucleoside. |
|
V75571 | 4'-C-Methyl-4-deoxyuridine | 1064364-21-1 | 4'-C-Methyl-4-deoxyuridine is an analogue of purine nucleoside. |
|
V75641 | 4'-C-Methyl-5-methoxyuridine | 2305415-71-6 | 4'-C-Methyl-5-methoxyuridine is a uridine analog. |
|
V55608 | 4'-C-Methyl-5-methylcytidine | 764644-12-4 | 4'-C-Methyl-5-methylcytidine is a cytosine nucleoside analog. |
|
V75579 | 4'-C-Methyl-N6-methyladenosine | 1064364-55-1 | 4'-C-Methyl-N6-methyladenosine is an adenine nucleoside analog. |
|
V55843 | 4'-Cyanouridine | 232589-05-8 | 4'-Cyanouridine is a uridine analog. |
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