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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
1-(5-O-Methoxytrityl-2-deoxy-β-D-xylofuranosyl)uracil V75672 1-(5-O-Methoxytrityl-2-deoxy-β-D-xylofuranosyl)uracil 2072145-82-3 1-(5-O-Methoxytrityl-2-deoxy-β-D-xylofuranosyl)uracil is an analogue of purine nucleoside.
1-(a-D-ribofuranosyl)uracil (alpha-D-Ribofuranoside,2,4(1H,3H)-pyrimidinedione-1) V52996 1-(aD-ribofuranosyl)uracil (alpha-D-Ribofuranoside,2,4(1H,3H)-pyrimidinedione-1) 3258-07-9 1-(aD-ribofuranosyl)uracil is an analogue of purine nucleoside.
1-(alpha-L-Threofuranosyl)cytosine V55507 1-(alpha-L-Threofuranosyl)cytosine 2166199-20-6 1-(alpha-L-Threofuranosyl)cytosine is an analogue of purine nucleoside.
1-(alpha-L-Threofuranosyl)thymine V75684 1-(alpha-L-Threofuranosyl)thymine 325683-84-9 1-(alpha-L-Threofuranosyl)thymine is an analogue of purine nucleoside.
1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one V75751 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one 59892-36-3 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is an analogue of purine nucleoside.
1-(β-D-Xylofuranosyl)-2-thiouracil V75918 1-(β-D-Xylofuranosyl)-2-thiouracil 2305416-17-3 1-(β-D-Xylofuranosyl)-2-thiouracil is an analogue of purine nucleoside.
1-(β-D-Xylofuranosyl)-5-methylcytosine V75636 1-(β-D-Xylofuranosyl)-5-methylcytosine 18492-10-9 1-(β-D-Xylofuranosyl)-5-methylcytosine is a cytosine nucleoside analog.
1-(β-D-Xylofuranosyl)-5-methyluracil V75930 1-(β-D-Xylofuranosyl)-5-methyluracil 52486-19-8 1-(β-D-Xylofuranosyl)-5-methyluracil is a thymidine analog.
1-(β-D-Xylofuranosyl)uracil V75765 1-(β-D-Xylofuranosyl)uracil 16535-78-7 1-(β-D-Xylofuranosyl)uracil is a uridine analog.
1-[3’-O-[(4,4’-Dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine V55845 1-[3'-O-[(4,4'-Dimethoxytriphenyl)methyl]-aL-threofuranosyl]-N4-benzoylcytosine 325683-91-8 1-[3'-O-[(4,4'-Dimethoxytriphenyl)methyl]-aL-threofuranosyl]-N4-benzoylcytosine is a cytosine nucleoside analogue.
1-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil V75533 1-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil 2095417-38-0 1-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil is an analogue of purine nucleoside.
1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil V75528 1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil 2095417-68-6 1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil is an analogue of purine nucleoside.
1-Amino-3’-deoxy-7,8-dihydro-8-oxoguanosine V56006 1-Amino-3'-deoxy-7,8-dihydro-8-oxoguanosine 2389988-59-2 1-Amino-3'-deoxy-7,8-dihydro-8-oxoguanosine is an analogue of purine nucleoside.
1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine V75947 1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine 2389988-21-8 1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is an analogue of purine nucleoside.
1-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine V75541 1-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine 2389988-22-9 1-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is an analogue of purine nucleoside.
1-Amino-8-benzyloxy-9-(β-D-xylofuranosyl)guanine V75563 1-Amino-8-benzyloxy-9-(β-D-xylofuranosyl)guanine 2389988-20-7 1-Amino-8-benzyloxy-9-(β-D-xylofuranosyl)guanine is an analogue of purine nucleoside.
1-Beta-D-arabinofuranosyl-5-iodouracil V55667 1-Beta-D-arabinofuranosyl-5-iodouracil 3052-06-0 1-Beta-D-arabinofuranosyl-5-iodouracil is an analogue of purine nucleoside.
1-Methyl-2'-O-methylinosine V55965 1-Methyl-2'-O-methylinosine 65150-69-8 1-Methyl-2'-O-methylinosine is an analogue of purine nucleoside.
1-O-Acetyl-2,3,5-tri-O-benzoyl-5(R)-C-methyl-D-ribo furanose V55620 1-O-Acetyl-2,3,5-tri-O-benzoyl-5(R)-C-methyl-D-ribo furanose 72159-45-6 1-O-Acetyl-2,3,5-tri-O-benzoyl-5(R)-C-methyl-D-ribo furanose is an analogue of purine nucleoside.
1-O-Acetyl-2-O-benzoyl-3-O-tert-butyldiphenylsilyl-L-threofuranose V55390 1-O-Acetyl-2-O-benzoyl-3-O-tert-butyldiphenylsilyl-L-threofuranose 1971879-01-2 1-O-Acetyl-2-O-benzoyl-3-O-tert-butyldiphenylsilyl-L-threofuranose is an analogue of purine nucleoside.
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