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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine V55955 5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine 910129-15-6 5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is an analogue of purine nucleoside.
5’-Deoxy-5-methyluridine V55908 5'-Deoxy-5-methyluridine 56971-08-5 5'-Deoxy-5-methyluridine is an analogue of purine nucleoside.
5'-Deoxy-N4,N4-dimethyl-5-fluorocytidine V75688 5'-Deoxy-N4,N4-dimethyl-5-fluorocytidine 933443-84-6 5'-Deoxy-N4,N4-dimethyl-5-fluorocytidine is an analogue of purine nucleoside.
5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite (N1-Methylpseudouridine CEP) V55909 5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite (N1-Methylpseudouridine CEP) 875302-45-7 5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is an analogue of purine nucleoside.
5'-DMT-3'-TBDMS-Bz-rA V53139 5'-DMT-3'-TBDMS-Bz-rA 81256-88-4 5'-DMT-3'-TBDMS-Bz-rA is a nucleoside with protective and modifying effects.
5'-DMT-3'-TBDMS-ibu-rG V53382 5'-DMT-3'-TBDMS-ibu-rG 81256-89-5 5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside for DNA.
5'-DMTr-2,2'-anhydrothymidine V55395 5'-DMTr-2,2'-anhydrothymidine 817623-11-3 5'-DMTr-2,2'-anhydrothymidine is an analogue of purine nucleoside.
5’-O-(4,4’-Dimethoxytrityl)-2’-beta-C-methyl adenosine V55957 5'-O-(4,4'-Dimethoxytrityl)-2'-beta-C-methyl adenosine 2305415-95-4 5'-O-(4,4'-Dimethoxytrityl)-2'-beta-C-methyl adenosine is an adenine nucleoside analogue.
5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine V75673 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine 1384253-67-1 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine is an adenine nucleoside analogue.
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine V55402 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine 302918-83-8 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine is an analogue of purine nucleoside.
5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine V55264 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine 103285-22-9 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine is a uridine analog.
5'-O-(4,4'-Dimethoxytrityl)-2'-Ot-butyldimethylsilyl adenosine V75659 5'-O-(4,4'-Dimethoxytrityl)-2'-Ot-butyldimethylsilyl adenosine 81794-13-0 5'-O-(4,4'-Dimethoxytrityl)-2'-Ot-butyldimethylsilyl adenosine is an adenine nucleoside analogue.
5'-O-(4,4'-Dimethoxytrityl)-3'-O-levulinyl-2'-deoxyadenosine V75705 5'-O-(4,4'-Dimethoxytrityl)-3'-O-levulinyl-2'-deoxyadenosine 2072145-67-4 5'-O-(4,4'-Dimethoxytrityl)-3'-O-levulinyl-2'-deoxyadenosine is an analogue of purine nucleoside.
5'-O-(4,4'-Dimethoxytrityl)-3'-O-methyluridine V75640 5'-O-(4,4'-Dimethoxytrityl)-3'-O-methyluridine 127212-40-2 5'-O-(4,4'-Dimethoxytrityl)-3'-O-methyluridine is a uridine analog.
5’-O-(4,4’-Dimethoxytrityl)-3’-O-t-butyldimethylsilyl adenosine V55937 5'-O-(4,4'-Dimethoxytrityl)-3'-Ot-butyldimethylsilyl adenosine 81794-12-9 5'-O-(4,4'-Dimethoxytrityl)-3'-Ot-butyldimethylsilyl adenosine is an adenine nucleoside analogue.
5’-O-(4,4’-Dimethoxytrityl)-5-methoxyuridine V55384 5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine 2095417-73-3 5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine is an analogue of purine nucleoside.
5’-O-(4,4’-Dimethoxytrityl)-N6-phenoxyacetyl adenosine V55862 5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl adenosine 121076-16-2 5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl adenosine is an adenine nucleoside analogue.
5’-O-(4,4-Dimethoxytrityl)-2’-O-methyl inosine (5'-O-(DIMETHOXYTRITYL)-2'-O-METHYLINOSINE) V55600 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl inosine (5'-O-(DIMETHOXYTRITYL)-2'-O-METHYLINOSINE) 128219-84-1 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl inosine is an analogue of purine nucleoside.
5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine V55415 5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluoro-6-chloroinosine 1612192-06-9 5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluoro-6-chloroinosine is an analogue of purine nucleoside.
5′-O-[(4-Cyanophenyl)methyl]-2′,3′-O-(1-methylethylidene)adenosine V55529 5′-O-[(4-Cyanophenyl)methyl]-2′,3′-O-(1-methylethylidene)adenosine 1134156-51-6 5′-O-[(4-Cyanophenyl)methyl]-2′,3′-O-(1-methylethylidene)adenosine is an adenine nucleoside analogue.
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