Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
![5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine (5'-O-(4,4'-DIMETHOXYTRITYL)ADENOSINE)](http://www.invivochem.com/upload/1124/V75590.png)
|
V75590 | 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine (5'-O-(4,4'-DIMETHOXYTRITYL)ADENOSINE) | 81352-25-2 | 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine is an adenine nucleoside analogue. |
![5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine](http://www.invivochem.com/upload/1124/hy-154198.png)
|
V55924 | 5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine | 112897-99-1 | 5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine is an analogue of purine nucleoside. |
|
V55562 | 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluoro-uridine | 160203-74-7 | 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluoro-uridine is an analogue of purine nucleoside. |
|
V55804 | 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-uridine | 42867-74-3 | 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-uridine is an analogue of purine nucleoside. |
|
V55359 | 5'-O-Acetyl-5-acetyloxymethyluridine | 2305416-11-7 | 5'-O-Acetyl-5-acetyloxymethyluridine is a thymidine analog. |
|
V55400 | 5'-O-Benzoyl-2'-O,4'-C-methyleneuridine | 293751-31-2 | 5'-O-Benzoyl-2'-O,4'-C-methyleneuridine is an analogue of purine nucleoside. |
|
V55429 | 5'-O-Benzoylthymidine | 65475-51-6 | 5'-O-Benzoylthymidine is a thymidine analog. |
|
V75759 | 5'-O-DMT-2'-deoxy-2'-fluoro-β-D-arabinouridine | 144822-63-9 | 5'-O-DMT-2'-deoxy-2'-fluoro-β-D-arabinouridine is a uridine analog. |
|
V53123 | 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine (5'-O-DMT-2'-O-TBDMS-ibu-rG) | 81279-39-2 | 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine can be used for silicon-based protection of nucleosides. |
|
V53124 | 5'-O-DMT-2'-O-TBDMS-Ac-rC | 121058-85-3 | 5'-O-DMT-2'-O-TBDMS-Ac-rC is a modified nucleoside that may be utilized to prepare DNA or RNA. |
|
V53380 | 5'-O-DMT-2'-O-TBDMS-Bz-rC | 81256-87-3 | 5'-O-DMT-2'-O-TBDMS-Bz-rC is a modified nucleoside that may be utilized to prepare DNA or RNA. |
|
V53095 | 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine | 81265-93-2 | 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is an adenosine analogue that can be used as an intermediate in oligonucleotide synthesis. |
|
V53283 | 5'-O-DMT-2'-O-TBDMS-rI | 127212-34-4 | 5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside that can be used for the synthesis of deoxyribonucleic acid or ribonucleic acid. |
|
V53030 | 5'-O-DMT-2'-TBDMS-Uridine | 81246-80-2 | 5'-O-DMT-2'-TBDMS-Uridine is a deoxyribonucleoside that may be utilized in the preparation /synthesis of oligonucleotides. |
|
V53141 | 5'-O-DMT-3'-O-TBDMS-Ac-rC | 123956-65-0 | 5'-O-DMT-3'-O-TBDMS-Ac-rC is a modified nucleoside that may be utilized to prepare DNA or RNA. |
|
V52939 | 5'-O-DMT-Bz-rA | 81246-82-4 | 5'-O-DMT-Bz-rA is an intermediate in the preparation /synthesis of cyclic dinucleotide compounds. |
|
V53097 | 5'-O-DMT-Bz-rC | 81246-76-6 | 5'-O-DMT-Bz-Rc is a modified nucleoside that may be utilized to prepare DNA or RNA. |
|
V53369 | 5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) | 40615-39-2 | 5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside analogue that may be utilized in the preparation of oligonucleotides. |
|
V53373 | 5'-O-DMT-ibu-dC | 100898-62-2 | 5'-O-DMT-ibu-dC may be utilized to prepare oligodeoxyribonucleotides. |
|
V55706 | 5'-O-DMT-ibu-rG (5'-O-DMT-N2-isobutyrylguanosine) | 81246-83-5 | 5'-O-DMT-ibu-rG is a useful model for the development of novel DNA-binding molecules for the development of potent and specific anticancer drugs. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
