Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V53376 | 5'-O-DMT-N2-DMF-dG | 40094-22-2 | 5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside that may be utilized in the preparation /synthesis of deoxyribonucleic acid or ribonucleotides. |
|
V75698 | 5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine | 171486-53-6 | 5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is a guanine nucleoside analog. |
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V52968 | 5'-O-DMT-N4-Ac-2'-F-dC | 159414-98-9 | 5'-O-DMT-3'-O-TBDMS-Ac-rC is a modified nucleoside that may be utilized to prepare DNA or RNA. |
|
V53096 | 5'-O-DMT-N4-Bz-2'-F-dC | 146954-77-0 | 5'-O-DMT-N4-Bz-2'-F-Dc is a nucleoside with protective and modifying effects. |
|
V53172 | 5'-O-DMT-N4-Bz-5-Me-dC | 104579-03-5 | 5'-O-DMT-N4-Bz-5-Me-dC is a modified nucleoside that may be utilized in the preparation /synthesis of deoxyribonucleic acid or ribonucleic acid. |
|
V53375 | 5'-O-DMT-N6-ibu-dA | 190834-10-7 | 5'-O-DMT-N6-ibu-dA may be utilized to prepare oligodeoxyribonucleotides. |
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V53371 | 5'-O-DMT-N6-Me-2'-dA | 98056-69-0 | 5'-O-DMT-N6-Me-2'-dA is a nucleoside with protective and modifying effects. |
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V53129 | 5'-O-DMT-PAC-dA | 110522-82-2 | 5'-O-DMT-PAC-dA may be utilized to prepare oligonucleotides. |
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V52969 | 5'-O-DMT-rI | 119898-59-8 | 5'-O-DMT-Ri may be utilized to prepare oligonucleotides. |
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V52971 | 5'-O-DMT-rU | 81246-79-9 | 5'-O-DMT-rU is a modified nucleoside that may be utilized to prepare RNA. |
|
V55592 | 5'-O-DMTr-2',2'-difluoro-dC(Bz)-3'-CED-phosphoramidite | 142808-44-4 | 5'-O-DMTr-2',2'-difluoro-dC(Bz)-3'-CED-phosphoramidite is an analogue of purine nucleoside. |
|
V75739 | 5'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite | 2348385-04-4 | 5'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite is an adenine nucleoside analogue. |
|
V75754 | 5'-O-DMTr-2'-OMeU-methyl phosphonamidite | 191786-64-8 | 5'-O-DMTr-2'-OMeU-methyl phosphonamidite is an analogue of purine nucleoside. |
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V55487 | 5'-O-DMTr-3'-deoxyuridine | 86234-42-6 | 5'-O-DMTr-3'-deoxyuridine is an analogue of purine nucleoside. |
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V55404 | 5'-O-DMTr-3'-deoxyuridine 2'-CED phosphoramidite | 161503-98-6 | 5'-O-DMTr-3'-deoxyuridine 2'-CED phosphoramidite is an analogue of purine nucleoside. |
|
V55450 | 5'-O-DMTr-3'-O-methyl uridine-3'-CED-phosphoramidite | 179479-05-1 | 5'-O-DMTr-3'-O-methyl uridine-3'-CED-phosphoramidite is a uridine analog. |
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V55366 | 5'-O-DMTr-5-iodo-2'-deoxyuridine (2'-Deoxy-5'-O-DMT-5-iodouridine) | 104375-88-4 | 5'-O-DMTr-5-iodo-2'-deoxyuridine is an analogue of purine nucleoside. |
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V56008 | 5'-O-DMTr-5-iodo-2'-dU-3'-CED phosphoramidite | 178925-48-9 | 5'-O-DMTr-5-iodo-2'-dU-3'-CED phosphoramidite is an analogue of purine nucleoside. |
|
V53044 | 5'-O-TBDMS-Bz-dA | 51549-39-4 | 5'-O-TBDMS-Bz-dA is a nucleoside with protective and modifying effects. |
|
V53054 | 5'-O-TBDMS-dA | 51549-30-5 | 5'-O-TBDMS-dA is a modified nucleoside that may be utilized to prepare DNA or RNA. |
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