Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V52910 | 5'-O-TBDMS-dG | 51549-33-8 | 5'-O-TBDMS-dG is a modified nucleoside that may be utilized in the preparation /synthesis of deoxyribonucleic acid or ribonucleic acid. |
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V53055 | 5'-O-TBDMS-dT | 40733-28-6 | 5'-O-TBDMS-dT is a nucleoside with protective and modifying effects. |
|
V53355 | 5'-O-TBDMS-dU | 76223-04-6 | 5'-O-TBDMS-dU may be utilized to prepare oligonucleotides. |
|
V55144 | 5'-O-TBDMS-N2-ibu-dG | 85326-10-9 | 5'-O-TBDMS-N2-ibu-dG is a nucleoside analogue that may be utilized to prepare lead compounds with anti-bovine viral diarrhea virus activity. |
|
V55577 | 5'-O-TBDPS-2,2'-anhydrouridine | 175013-46-4 | 5'-O-TBDPS-2,2'-anhydrouridine is an analogue of purine nucleoside. |
|
V55501 | 5'-O-TBDPS-5-methyl-2,2'-anhydrouridine | 171763-19-2 | 5'-O-TBDPS-5-methyl-2,2'-anhydrouridine is an analogue of purine nucleoside. |
|
V55993 | 5'-O-Triphenylmethyl-2'-deoxyuridine | 14270-73-6 | 5'-O-Triphenylmethyl-2'-deoxyuridine is an analogue of purine nucleoside. |
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V55615 | 5'-ODMT cEt G Phosphoramidite (Amidite) | 945628-66-0 | 5'-ODMT cEt G Phosphoramidite Amidite is a potent nucleic acid analog. |
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V56002 | 5'-ODMT cEt m5U Phosphoramidite (Amidite) | 1197033-22-9 | 5'-ODMT cEt m5U Phosphoramidite Amidite is a locked nucleic acid (LNA) analog. |
|
V55785 | 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) | 1197033-19-4 | 5'-ODMT cEt N-Bz A Phosphoramidite Amidite is a locked nucleic acid (LNA) analog. |
|
V55284 | 5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite) | 1197033-17-2 | 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is a potent nucleic acid analog. |
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V75728 | 5'-Protected 2,2'-anhydrouridine | 173170-12-2 | 5'-Protected 2,2'-anhydrouridine is an analogue of purine nucleoside. |
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V55892 | 5,6-Dihydro-ara-uridine | 30100-83-5 | 5,6-Dihydro-ara-uridine is an analogue of purine nucleoside. |
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V55417 | 5-(2,3,5-Tri-O-benzyl-beta-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine | 1846584-69-7 | 5-(2,3,5-Tri-O-benzyl-beta-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine is an analogue of purine nucleoside. |
|
V55675 | 5-(2-Amino-2-oxoethyl)uridine | 29569-30-0 | 5-(2-Amino-2-oxoethyl)uridine is an analogue of purine nucleoside. |
|
V55376 | 5-(2-Hydroxyethyl)-2'-deoxyuridine | 90301-60-3 | 5-(2-Hydroxyethyl)-2'-deoxy uridine is an analogue of purine nucleoside. |
|
V55931 | 5-(2-Hydroxyethyl)cytidine | 137248-64-7 | 5-(2-Hydroxyethyl)cytidine is a cytosine nucleoside analogue. |
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V55969 | 5-(2-Hydroxyethyl)uridine | 102691-28-1 | 5-(2-Hydroxyethyl)uridine is a thymidine analogue. |
|
V75777 | 5-(3-Azidopropyl)uridine | 1354419-08-1 | 5-(3-Azidopropyl)uridine is a thymidine analog. |
|
V55653 | 5-(Aminomethyl)-2′,3′-O-(1-methylethylidene)-2-thiouridine | 1428903-07-4 | 5-(Aminomethyl)-2′,3′-O-(1-methylethylidene)-2-thiouridine is an analogue of purine nucleoside. |
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