Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V55681 | 5-Fluoro-4'-C-methyluridine | 660845-69-2 | 5-Fluoro-4'-C-methyluridine is a uridine analog. |
|
V55389 | 5-Fluoro-4'-thiouridine | 56527-42-5 | 5-Fluoro-4'-thiouridine is an analogue of purine nucleoside. |
|
V55267 | 5-Fluoro-5'-deoxycytidine (5-F-5'-deoxycytidine) | 66335-38-4 | 5-Fluoro-5'-deoxycytidine is a cytosine nucleoside analog. |
|
V55354 | 5-Formyl-2'-O-methylcytidine | 176858-79-0 | 5-Formyl-2'-O-methylcytidine is a cytosine nucleoside analog. |
|
V55922 | 5-Furan-2-yl-2'-O-methyl uridine | 2095417-32-4 | 5-Furan-2-yl-2'-O-methyl uridine is an analogue of purine nucleoside. |
|
V75602 | 5-Hydroxy-2'-O-methyluridine | 2030403-78-0 | 5-Hydroxy-2'-O-methyluridine is an analogue of purine nucleoside. |
|
V75586 | 5-Hydroxy-arabinouridine | 69321-95-5 | 5-Hydroxy-arabinouridine is an analogue of purine nucleoside. |
|
V75593 | 5-Hydroxymethyl xylouridine | 52448-09-6 | 5-Hydroxymethyl xylouridine is a thymidine analog. |
|
V55484 | 5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine | 58479-71-3 | 5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is an analogue of purine nucleoside. |
|
V55926 | 5-Hydroxymethyl-2'-O-(2-methoxyethyl)uridine | 2095417-51-7 | 5-Hydroxymethyl-2'-O-(2-methoxyethyl)uridine is an analogue of purine nucleoside. |
|
V75517 | 5-Hydroxymethyl-2'-β-C-methyluridine | 2305415-92-1 | 5-Hydroxymethyl-2'-β-C-methyluridine is a thymidine analog. |
|
V75622 | 5-Hydroxymethyl-arauridine | 28608-82-4 | 5-Hydroxymethyl-arauridine is a thymidine analog. |
|
V53313 | 5-Hydroxyuridine (OHUrd) | 957-77-7 | 5-Hydroxyuridine (OHUrd) is an analogue of purine nucleoside. |
|
V55336 | 5-Iodo-2'-O-methylcytidine | 847650-69-5 | 5-Iodo-2'-O-methylcytidine is a cytosine nucleoside analog. |
|
V75565 | 5-Iodo-2'-β-C-methyl cytidine | 2072145-60-7 | 5-Iodo-2'-β-C-methyl cytidine is an analogue of purine nucleoside. |
|
V75519 | 5-Iodo-2'-β-C-methyl uridine | 1203461-96-4 | 5-Iodo-2'-β-C-methyl uridine is a uridine analog. |
|
V55905 | 5-Iodo-3'-deoxy-3'-fluorouridine | 2072145-21-0 | 5-Iodo-3'-deoxy-3'-fluorouridine is an analogue of purine nucleoside. |
|
V55282 | 5-Iodo-cytidine (5-Iodo-D-cytidine) | 1147-23-5 | 5-Iodo-cytidine (5-Iodo-D-cytidine) is an analogue of purine nucleoside. |
|
V52981 | 5-Iodouridine (5-iodo-uridine) | 1024-99-3 | 5-Iodouridine is an analogue of purine nucleoside. |
|
V55525 | 5-Me-3'-dU-2'-phosphoramidite | 142103-12-6 | 5-Me-3'-dU-2'-phosphoramidite is an analogue of purine nucleoside. |
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