Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V55610 | 5-Methoxy cytidine | 37805-90-6 | 5-Methoxy cytidine is a cytosine nucleoside analog. |
|
V55465 | 5-Methoxy-2-thiouridine | 30771-43-8 | 5-Methoxy-2-thiouridine is an analogue of purine nucleoside. |
|
V55537 | 5-Methoxy-4-thiouridine | 37805-89-3 | 5-Methoxy-4-thiouridine is an analogue of purine nucleoside. |
|
V55351 | 5-Methoxycarbonyl methyl uridine | 29428-50-0 | Methyl 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate is an analogue of purine nucleoside. |
|
V75603 | 5-Methoxycarbonylmethyl-2'-O-methyluridine (1,2,3,4-tetrahydro-1-(2-O-methyl-BETA-D-ribofuranosyl)-2,4-dioxo-5 -pyrimidine methyl acetate) | 60197-31-1 | 5-Methoxycarbonylmethyl-2'-O-methyluridine is a thymidine analogue. |
|
V55480 | 5-Methoxycarbonylmethyl-2-thiouridine | 20299-15-4 | 5-Methoxycarbonylmethyl-2-thiouridine is an analogue of purine nucleoside. |
|
V55374 | 5-Methoxymethyluridine | 82448-44-0 | 5-Methoxymethyluridine is a thymidine analogue. |
|
V55270 | 5-Methoxyuridine (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H ,3H)-diketone) | 35542-01-9 | 5-Methoxyuridine is an analogue of purine nucleoside. |
|
V55626 | 5-Methyl-2'-O,4'-C-methylenecytidine | 847650-87-7 | 5-Methyl-2'-O,4'-C-methylenecytidine is a cytosine nucleoside analog. |
|
V55852 | 5-Methyl-2′-O-methyl-uridine (2'-O-Methyl-5-methyluridine) | 55486-09-4 | 5-Methyl-2′-O-methyl-uridine (2'-O-methyl-5-methyluridine) is a thymidine analogue. |
|
V75598 | 5-Methyl-2′-O-methylcytidine (2'-methoxy-5-methylcytidine) | 113886-70-7 | 5-Methyl-2′-O-methylcytidine is an analogue of purine nucleoside. |
|
V55408 | 5-Methyl-2-thio-xylo-uridine | 246857-26-1 | 5-Methyl-2-thio-xylo-uridine is an analogue of purine nucleoside. |
|
V56021 | 5-Methyl-2-thiouridine (2-Thio-5-methyluridine) | 32738-09-3 | 5-Methyl-2-thiouridine (2-Thio-5-methyluridine) is an analogue of purine nucleoside. |
|
V55832 | 5-Methyl-4'-thiocytidine | 1312295-87-6 | 5-Methyl-4'-thiocytidine is an analogue of purine nucleoside. |
|
V55837 | 5-Methyl-4'-thiouridine | 13406-51-4 | 5-Methyl-4'-thiouridine is an adenine nucleoside analog. |
|
V55575 | 5-Methyl-4-thiouridine | 49555-43-3 | 5-Methyl-4-thiouridine is an analogue of purine nucleoside. |
|
V55593 | 5-Methylcyclocytidine hydrochloride (5-Methylcyclocytidine hydrochlorine) | 51391-96-9 | 5-Methylcyclocytidine HCl is an analogue of purine nucleoside. |
|
V55468 | 5-N-Boc-aminomethyluridine | 2305415-73-8 | 5-N-Boc-aminomethyluridine is a thymidine analogue. |
|
V75612 | 5-Naphthyl-beta-methylaminocarbony-2'-O-methyluridine | 1675178-56-9 | 5-Naphthyl-beta-methylaminocarbony-2'-O-methyluridine is a thymidine analogue. |
|
V55987 | 5-Naphthyl-beta-methylaminocarbony-3'-O-acetyl-2'-O-methyl-5'-O-DMTr-uridine | 2095417-00-6 | 5-Naphthyl-beta-methylaminocarbony-3'-O-acetyl-2'-O-methyl-5'-O-DMTr-uridine is a uridine analog. |
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