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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
5-Naphthyl-β-methylaminocarbony-3'-O-acetyl-2'-O-methyluridine V75916 5-Naphthyl-β-methylaminocarbony-3'-O-acetyl-2'-O-methyluridine 2095417-03-9 5-Naphthyl-β-methylaminocarbony-3'-O-acetyl-2'-O-methyluridine is a thymidine analogue.
5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone V75948 5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone 59892-37-4 5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is an analogue of purine nucleoside.
5-Nitro-1-(3-azido-3-deoxy-β-D-ribofuranosyl)-2(1H)-pyridinone V75614 5-Nitro-1-(3-azido-3-deoxy-β-D-ribofuranosyl)-2(1H)-pyridinone 2072145-26-5 5-Nitro-1-(3-azido-3-deoxy-β-D-ribofuranosyl)-2(1H)-pyridinone is an analogue of purine nucleoside.
5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone V55834 5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone 130222-84-3 5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone is an analogue of purine nucleoside.
5-O-Benzoyl-1,2,3-tri-O-acetyl-4-C-methyl-D-ribofuranose V55437 5-O-Benzoyl-1,2,3-tri-O-acetyl-4-C-methyl-D-ribofuranose 503543-44-0 5-O-Benzoyl-1,2,3-tri-O-acetyl-4-C-methyl-D-ribofuranose is an analogue of purine nucleoside.
5-O-Benzoyl-1,2-di-O-isopropylidene-3-keto-alpha-D-xylofuranoside (5-O-Benzoyl-1,2-O-(1-methylethylidene)pentofuranos-3-ulose) V55375 5-O-Benzoyl-1,2-di-O-isopropylidene-3-keto-alpha-D-xylofuranoside (5-O-Benzoyl-1,2-O-(1-methylethylidene)pentofuranos-3-ulose) 6698-46-0 5-O-Benzoyl-1,2-di-O-isopropylidene-3-keto-alpha-D-xylofuranoside is an analogue of purine nucleoside.
5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose (1,2-O-(异丙亚基)-ALPHA-D-呋喃木糖 5-苯甲酸酯) V55990 5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose 6022-96-4 5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is an analogue of purine nucleoside.
5-O-TBDMS-N4-Benzoyl-2-deoxycytidine V52975 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine 51549-36-1 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside that may be utilized in the preparation /synthesis of deoxyribonucleic acid or ribonucleic acid.
5-O-TBDPS-1,2-di-O-isopropy lidene-3-keto-alpha-D-xylofuranoside V56007 5-O-TBDPS-1,2-di-O-isopropy lidene-3-keto-alpha-D-xylofuranoside 75783-45-8 5-O-TBDPS-1,2-di-O-isopropy lidene-3-keto-alpha-D-xylofuranoside is an analogue of purine nucleoside.
5-Phenylcytidine V75720 5-Phenylcytidine 83866-19-7 5-Phenylcytidine is a cytosine nucleoside analog.
5-Pyrrolidinomethyluridine V55689 5-Pyrrolidinomethyluridine 1613530-41-8 5-Pyrrolidinomethyluridine is an analogue of purine nucleoside.
5-Vinylcytidine V55582 5-Vinylcytidine 1846584-62-0 5-Vinylcytidine is a cytosine nucleoside analogue.
5-β-D-Ribofuranosyl-2(1H)-pyridinone V75537 5-β-D-Ribofuranosyl-2(1H)-pyridinone 188871-50-3 5-β-D-Ribofuranosyl-2(1H)-pyridinone is an analogue of purine nucleoside.
6-(1-Piperazinyl)-9-β-D-ribofuranosyl-9H-purine V75956 6-(1-Piperazinyl)-9-β-D-ribofuranosyl-9H-purine 121370-61-4 6-(1-Piperazinyl)-9-β-D-ribofuranosyl-9H-purine is an analogue of purine nucleoside.
6-(2-Furanyl)-9-β-D-ribofuranosyl-9H-purine V75760 6-(2-Furanyl)-9-β-D-ribofuranosyl-9H-purine 352025-81-1 6-(2-Furanyl)-9-β-D-ribofuranosyl-9H-purine is an analogue of purine nucleoside.
6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[1,2-c]pyrimidin-5-one V75744 6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[1,2-c]pyrimidin-5-one 2095417-54-0 6-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-3-(2-oxopropyl)imidazo[1,2-c]pyrimidin-5 (6H)-one is an analogue of purine nucleoside.
6-(4-Morpholinyl)-9-β-D-ribofuranosyl-9H-purine V75526 6-(4-Morpholinyl)-9-β-D-ribofuranosyl-9H-purine 52940-48-4 6-(4-Morpholinyl)-9-β-D-ribofuranosyl-9H-purine is an analogue of purine nucleoside.
6-(Thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside V55477 6-(Thiophen-3-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside 1612191-90-8 6-(Thiophen-3-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside is an analogue of purine nucleoside.
6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one V75944 6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one 85426-86-4 6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one is an analogue of purine nucleoside.
6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine V75695 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine 100644-69-7 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog.
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