Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V75615 | 6-O-Methyldeoxyguanosine (O6-Methyl-2′-deoxyguanosine) | 964-21-6 | O6-Methyldeoxy guanosine; DNA adduct is an analogue of purine nucleoside. |
|
V51312 | 6-O-Methylinosine | 5746-29-2 | 6-O-Methylinosine is an analog of hypoxanthine. |
|
V55427 | 7'-O-DMT-morpholino thymine | 143485-05-6 | 7'-O-DMT-morpholino thymine is an adenine nucleoside analogue. |
|
V75613 | 7'-O-DMT-morpholino uracil | 1127343-02-5 | 7'-O-DMT-morpholino uracil is a uridine analog. |
|
V55504 | 7'-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) | 914361-76-5 | 7'-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) is an analogue of purine nucleoside. |
|
V56024 | 7,8-Dihydro-8-oxo-7-propargyl guanosine | 2763084-98-4 | 7,8-Dihydro-8-oxo-7-propargyl guanosine is an analogue of purine nucleoside. |
|
V55828 | 7,8-Dihydro-8-oxo-7-propargyl-3'-deoxyguanosine | 2389988-54-7 | 7,8-Dihydro-8-oxo-7-propargyl-3'-deoxy guanosine is an analogue of purine nucleoside. |
|
V55442 | 7,8-Dihydro-8-oxo-7-propargyl-3'-deoxy-3'-fluoro guanosine | 2389988-55-8 | 7,8-Dihydro-8-oxo-7-propargyl-3'-deoxy-3'-fluoro guanosine is an analogue of purine nucleoside. |
|
V55371 | 7,8-Dihydro-8-oxo-7-propargyl-3'-deoxy-3'-fluoro-xylo-guanosine | 2389988-56-9 | 7,8-Dihydro-8-oxo-7-propargyl-3'-deoxy-3'-fluoro-xylo-guanosine is an analogue of purine nucleoside. |
![7-(2,3-Anhydro-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine](http://www.invivochem.com/upload/1124/V75711.png)
|
V75711 | 7-(2,3-Anhydro-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine | 40627-31-4 | 7-(2,3-Anhydro-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is an analogue of purine nucleoside. |
![7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine](http://www.invivochem.com/upload/1124/V75576.png)
|
V75576 | 7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine | 652965-07-6 | 7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine nucleoside analog. |
![7-(2-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine](http://www.invivochem.com/upload/1124/V75961.png)
|
V75961 | 7-(2-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine | 93366-89-3 | 7-(2-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is an analogue of purine nucleoside. |
![7-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine](http://www.invivochem.com/upload/1124/V75516.png)
|
V75516 | 7-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine | 40725-89-1 | 7-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is an analogue of purine nucleoside. |
|
V75536 | 7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine | 2389988-33-2 | 7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is an analogue of purine nucleoside. |
|
V75747 | 7-Allyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine | 2389988-25-2 | 7-Allyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is an analogue of purine nucleoside. |
|
V55456 | 7-Cyano-7-deaza-2'-deoxyguanosine | 199859-58-0 | 7-Cyano-7-deaza-2'-deoxy guanosine is a guanine nucleoside analog. |
|
V55854 | 7-Cyano-7-deazaguanosine | 61210-21-7 | 7-Cyano-7-deazaguanosine is an analogue of purine nucleoside. |
|
V75730 | 7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine | 2763085-07-8 | 7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is an analogue of purine nucleoside. |
|
V75557 | 7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine | 2389988-23-0 | 7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is an analogue of purine nucleoside. |
|
V55142 | 7-Deaza-2',3'-dideoxyadenosine | 40627-30-3 | 7-Deaza-2',3'-dideoxyadenosine may be utilized in the preparation /synthesis of oligodeoxyribonucleotides. |
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