Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V55370 | 7-Deazaguanosine | 62160-23-0 | 7-Deazaguanosine is an analogue of purine nucleoside. |
|
V75776 | 7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine | 2389988-43-4 | 7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is an analogue of purine nucleoside. |
|
V55121 | 7-Iodo-2',3'-dideoxy-7-deaza-guanosine | 114748-67-3 | 7-Iodo-2',3'-dideoxy-7-deazaadenosine is a dideoxy nucleoside that may be utilized in DNA synthesis and sequencing reactions. |
|
V52982 | 7-Iodo-2',3'-dideoxy-7-deazaadenosine | 114748-70-8 | 7-Iodo-2',3'-dideoxy-7-deazaadenosine is a dideoxy nucleoside that may be utilized in DNA synthesis and sequencing reactions. |
|
V55674 | 7-Methyl wyosine | 577773-09-2 | 7-Methyl wyosine is an analogue of purine nucleoside. |
|
V75959 | 7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine | 2389988-45-6 | 7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is an analogue of purine nucleoside. |
|
V75554 | 7-n-Propyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine | 2389988-44-5 | 7-n-Propyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is an analogue of purine nucleoside. |
|
V75529 | 7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine | 2389988-31-0 | 7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is an analogue of purine nucleoside. |
|
V53276 | 7-TFA-ap-7-Deaza-dA | 178420-75-2 | 7-TFA-ap-7-Deaza-dA is a modified nucleoside that may be utilized in DNA/RNA synthesis. |
|
V55151 | 7-TFA-ap-7-Deaza-ddA | 114748-71-9 | 7-TFA-ap-7-Deaza-ddA (compound 19c, US20060281100A1) is a nucleotide analogue that may be utilized to prepare thiophosphoric acid nucleotide dye terminators. |
|
V55141 | 7-TFA-ap-7-Deaza-ddG | 114748-68-4 | 7-TFA-ap-7-Deaza-ddG (compound 19d, US20060281100A1) is a nucleotide analogue that may be utilized to prepare thiophosphoric acid nucleotide dye terminators. |
|
V53324 | 7-TFA-ap-7-Deaza-dG | 666847-77-4 | 5'-O-TBDMS-dG is a modified nucleoside that may be utilized in the preparation /synthesis of deoxyribonucleic acid or ribonucleic acid. |
|
V75609 | 8-(Methylamino)adenosine | 13389-13-4 | 8-(Methylamino)adenosine is an adenine nucleoside analog. |
|
V51792 | 8-(Methylthio)guanosine | 2104-66-7 | 8-(Methylthio)guanosine is an analog of guanosine. |
|
V51790 | 8-(Phenylmethoxy)guanosine | 3868-36-8 | 8-(Phenylmethoxy)guanosine is an analog of guanosine. |
|
V55855 | 8-Allyloxyadenosine | 2095417-69-7 | 8-Allyloxyadenosine is an adenine nucleoside analogue. |
|
V55786 | 8-Allyloxyguanosine | 126138-81-6 | 8-Allyloxyguanosine is an analogue of purine nucleoside. |
|
V55440 | 8-Allylthioadenosine | 75059-23-3 | 8-Allylthioadenosine is an adenine nucleoside analog. |
|
V55830 | 8-Allylthioguanosine | 126092-30-6 | 8-Allylthioguanosine is an analogue of purine nucleoside. |
|
V55783 | 8-Amino-2′-deoxyadenosine | 13389-09-8 | 8-Amino-2′-deoxyadenosine is an analogue of purine nucleoside. |
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