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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
8-Chloro-arabinoadenosine V75700 8-Chloro-arabinoadenosine 769872-68-6 8-Chloro-arabinoadenosine is an analogue of purine nucleoside.
8-Chloroguanosine V55917 8-Chloroguanosine 2104-68-9 8-Chloroguanosine is an analogue of purine nucleoside.
8-Chloroinosine V55357 8-Chloroinosine 116285-77-9 8-Chloroinosine is an analogue of purine nucleoside.
8-Hydrazinoadenosine V55514 8-Hydrazinoadenosine 3868-34-6 8-Hydrazinoadenosine is an analogue of purine nucleoside.
8-Hydroxy-xyloguanosine V55314 8-Hydroxy-xyloguanosine 2390368-04-2 8-Hydroxy-xyloguanosine is an analogue of purine nucleoside.
8-Hydroxymethyl guanosine V51791 8-Hydroxymethyl guanosine 54898-41-8 8-Hydroxymethyl guanosine is a guanosine analog.
8-Methoxyadenosine V55547 8-Methoxyadenosine 3969-27-5 8-Methoxyadenosine is an adenine nucleoside analog.
8-Methyl-2'-deoxyadenosine V75652 8-Methyl-2'-deoxyadenosine 85562-60-3 8-Methyl-2'-deoxyadenosine is an analogue of purine nucleoside.
8-Methyl-2’-deoxyguanosine V55875 8-Methyl-2'-deoxyguanosine 85819-69-8 8-Methyl-2'-deoxyguanosine is an analogue of purine nucleoside.
8-Methyladenosine V55461 8-Methyladenosine 56973-12-7 8-Methyladenosine is an analogue of purine nucleoside.
8-Methylguanosine V55704 8-Methylguanosine 36799-17-4 8-Methylguanosine is an analogue of purine nucleoside.
8-Methylthio-adenosine V55849 8-Methylthio-adenosine 29836-01-9 8-Methylthio-adenosine is an adenine nucleoside analog.
8-Nitro-D-guanosine V51788 8-Nitro-D-guanosine 337536-53-5 8-Nitro-D-guanosine is an analog of guanosine.
9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)-9H-purine V75527 9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)-9H-purine 109304-16-7 9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)-9H-purine is an analogue of purine nucleoside.
9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine V55411 9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine 1347118-41-5 9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is an analogue of purine nucleoside.
9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine V55623 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine 2072145-40-3 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine is an analogue of purine nucleoside.
9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-6-chloropurine V55299 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-6-chloropurine 2072145-46-9 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-6-chloropurine is an analogue of purine nucleoside.
9-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purin-2-amine V75913 9-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purin-2-amine 1345969-99-4 9-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purin-2-amine is an analogue of purine nucleoside.
9-(2-Deoxy-beta-D-ribofuranosyl)-6-methylpurine V55900 9-(2-Deoxy-beta-D-ribofuranosyl)-6-methylpurine 16006-64-7 (2R,3S,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3-ol (9-(2-Deoxy-beta-D-ribofuranosyl)-6 -methylpurine) is an analogue of purine nucleoside.
9-(2-Deoxy-β-D-threo-pentofuranosyl)-9H-purin-6-amine V75950 9-(2-Deoxy-β-D-threo-pentofuranosyl)-9H-purin-6-amine 13276-53-4 9-(2-Deoxy-β-D-threo-pentofuranosyl)-9H-purin-6-amine is an adenine nucleoside analog.
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