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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
9-(2-O-Acetyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)-6-chloro-9H-purine V75725 9-(2-O-Acetyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)-6-chloro-9H-purine 132370-61-7 9-(2-O-Acetyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)-6-chloro-9H-purine is an analogue of purine nucleoside.
9-(2-β-C-Methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine V75538 9-(2-β-C-Methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine 2095417-45-9 9-(2-β-C-Methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine is an analogue of purine nucleoside.
9-(2-β-C-Methyl-β-D-ribofuranosyl)purine V75952 9-(2-β-C-Methyl-β-D-ribofuranosyl)purine 690269-86-4 9-(2-β-C-Methyl-β-D-ribofuranosyl)purine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine V55445 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine 124775-29-7 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenylpyridin-3-yl)purine V75953 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenylpyridin-3-yl)purine 1612191-96-4 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenylpyridin-3-yl)purine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine V75669 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine 1612191-89-5 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(naphthalen-1-yl)purine V75525 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(naphthalen-1-yl)purine 1612191-92-0 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(naphthalen-1-yl)purine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine V75955 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine 1612191-93-1 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine V75927 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine 1612191-95-3 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl) pyridin-3-yl]purine V75651 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl) pyridin-3-yl]purine 1612191-99-7 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl) pyridin-3-yl]purine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine V75553 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine 1612191-98-6 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-methyl-9H-purine V75761 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-methyl-9H-purine 1612191-88-4 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-methyl-9H-purine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine V75928 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine 1612191-91-9 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine is an analogue of purine nucleoside.
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine V75940 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine 1612192-04-7 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine is an analogue of purine nucleoside.
9-(β-D-Xylofuranosyl)adenine V75905 9-(β-D-Xylofuranosyl)adenine 524-69-6 9-(β-D-Xylofuranosyl)adenine is an adenine nucleoside analog.
9-(β-D-Xylofuranosyl)guanine V75919 9-(β-D-Xylofuranosyl)guanine 27462-39-1 9-(β-D-Xylofuranosyl)guanine is a guanine nucleoside analog.
9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine V55405 9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-bL-ribofuranosyl)-6-chloropurine 2095417-30-2 9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-bL-ribofuranosyl)-6-chloropurine is an analogue of purine nucleoside.
9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin V75914 9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin 103884-98-6 2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin) is an analogue of purine nucleoside.
Ac-dA Phosphoramidite V55145 Ac-dA Phosphoramidite 1027734-01-5 Ac-dA Phosphoramidite is a phosphoramidite monomer that may be utilized in the preparation of oligonucleotides.
Adenosine 5′-monophosphoramidate sodium V52917 Adenosine 5′-monophosphoramidate sodium 102029-68-5 Adenosine 5′-monophosphoramidate sodium is an adenosine analogue that could be utilized as an intermediate in nucleotide synthesis.
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