Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V75524 | Adenosine 5′-O-1-thiotriphosphate | 29220-54-0 | Adenosine 5′-O-(1-thiotriphosphate) is an α-phosphate modified adenosine nucleotide. |
|
V55346 | Adenosine-2-carboxamide | 70255-72-0 | Adenosine-2-carboxamide is an analogue of purine nucleoside. |
|
V83095 | Adipyl-arginine | ||
|
V55519 | Alpha-5-Methyluridine | 3258-09-1 | Alpha-5-Methyluridine is an analogue of purine nucleoside. |
|
V52989 | Alpha-Adenosine | 5682-25-7 | Alpha-Adenosine is an analogue of purine nucleoside. |
|
V53332 | Alpha-Guanosine | 15398-66-0 | Alpha-Guanosine is an analogue of purine nucleoside. |
|
V75704 | Alpha-inosine | 38183-47-0 | Alpha-inosine is an analogue of purine nucleoside. |
|
V75542 | Antiangiogenic agent 2 | 2422149-84-4 | Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase with IC50 of 39.71 μM. |
|
V55281 | Arabinosylhypoxanthine (Hypoxanthine, 9-beta-D-arabinofuranosyl-) | 7013-16-3 | Arabinosylhypoxanthine is an analogue of purine nucleoside. |
|
V55936 | Arabinosylisocytosine (NSC 529488) | 10212-30-3 | 2-Amino-1-β-D-arabinofuranosyl-4(1H)-pyrimidinone is an analogue of purine nucleoside. |
|
V52931 | Bz-rA Phosphoramidite (DMT-2'O-TBDMS-rA(bz) Phosphoramidite) | 104992-55-4 | Bz-rA Phosphoramidite can be used for modification of nucleotides. |
|
V84120 | CCPA hemihydrate (2-Chloro-N6-cyclopentyladenosine hemihydrate) | 1217443-91-8 | |
|
V85842 | Centanamycin (ML-970; AS-I-145; NSC 716970) | 413577-16-9 | |
|
V55278 | Chloropurine riboside (6-Chloropurine riboside) | 5399-87-1 | Chloropurine riboside is an analogue of purine nucleoside. |
|
V55457 | Detiviciclovir (AM365) | 220984-26-9 | Detiviclovir (AM365) is an antiviral nucleoside analog. |
|
V55129 | dGTP (2'-Deoxyguanosine-5'-triphosphate) | 2564-35-4 | dGTP (2'-Deoxyguanosine-5'-triphosphate) is a guanosine nucleotide used in the synthesis/preparation of deoxyribonucleic acid. |
|
V75633 | Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) | 7481-88-1 | Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) is an analogue of purine nucleoside. |
|
V55128 | Diguanosine 5′-triphosphate (Gp3G) | 6674-45-9 | Diguanosine 5′-triphosphate (Gp3G) is a dinucleoside triphosphate. |
|
V55471 | Dihydrodeoxyuridine (H2dUrd) | 5626-99-3 | Dihydrodeoxyuridine (H2dUrd) is an analogue of purine nucleoside. |
|
V55146 | DMT-2'-F-Bz-dA | 136834-21-4 | DMT-2'-F-Bz-dA may be utilized in the preparation /synthesis of nucleotides and nucleic acids. |
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