Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V55991 | DMT-2'-F-Bz-dC | 154771-33-2 | DMT-2'-F-Bz-dC is a cytosine nucleoside analog. |
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V53140 | Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite) | 159414-99-0 | Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite monomer that may be utilized in the preparation of cyclic purine dinucleotides. |
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V55424 | DMT-2'-F-dC(Bz)-CE-Phosphoramidite | 182495-83-6 | DMT-2'-F-dC(Bz)-CE-Phosphoramidite is an analogue of purine nucleoside. |
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V55876 | DMT-2'-O-MOE-rA(Bz) phosphoramidite | 251647-53-7 | DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analogue. |
|
V55431 | DMT-2'-OMe-Bz-C (N-(1-((2R,3R,4R,5R)-5-(bis(4-methoxyphenyl)(phenyl)methoxy)methyl (yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide) | 110764-74-4 | DMT-2'-OMe-Bz-C is a cytosine nucleoside analog. |
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V53137 | DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) | 144089-97-4 | DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that may be utilized to prepare 4'-modified 2'-deoxy-2'-fluorouridine. |
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V53028 | DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) | 146954-75-8 | DMT-2′Fluoro-dU Phosphoramidite can be used for nucleoside modification. |
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V52912 | DMT-dC(ac) Phosphoramidite | 154110-40-4 | DMT-dC(ac) Phosphoramidite is a modified phosphoramidite monomer that may be utilized in the preparation /synthesis of oligonucleotides. |
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V53094 | DMT-dC(bz) Phosphoramidite | 102212-98-6 | DMT-dC(bz) Phosphoramidite is widely used to synthesize DNA. |
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V56554 | DMT-dC(bz) Phosphoramidite-13C9,15N3 | 2483830-14-2 | DMT-dC(bz) Phosphoramidite-13C9,15N3 is 13C and 15N labeled DMT-dC(bz) Phosphoramidite. |
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V53023 | DMT-dG(dmf) Phosphoramidite | 330628-04-1 | DMT-dG(dmf) Phosphoramidite is a phosphoramidite monomer that may be utilized in the preparation of oligonucleotides. |
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V53018 | DMT-dG(ib) Phosphoramidite | 93183-15-4 | DMT-dG(ib) Phosphoramidite is widely used to synthesize DNA. |
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V56552 | DMT-dG(ib) Phosphoramidite-13C10,15N5 | 2483830-16-4 | DMT-dG(ib) Phosphoramidite-13C10,15N5 is 13C and 15N labeled DMT-dG(ib) Phosphoramidite. |
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V52888 | DMT-dI (5'-O-DMT-dI; 2'-Deoxy-5'-O-DMT-inosine) | 93778-57-5 | DMT-dI (5'-O-DMT-dI) is a deoxyuridine that may be utilized in the preparation of convertible nucleoside analogues. |
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V53330 | DMT-dI Phosphoramidite | 141684-35-7 | DMT-dI Phosphoramidite is a modified phosphoramidite monomer that may be utilized in the preparation /synthesis of oligonucleotides. |
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V84519 | DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite | 143774-48-5 | |
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V55511 | DMTr-dH2U-amidite | 151503-28-5 | DMTr-dH2U-amidite is an analogue of purine nucleoside. |
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V55688 | DMTr-LNA-C(Bz)-3-CED-phosphoramidite | 206055-78-9 | DMTr-LNA-C(Bz)-3-CED-phosphoramidite is an analogue of purine nucleoside. |
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V55403 | DMTr-TNA-C(Bz)-amidite | 325683-96-3 | DMTr-TNA-C(Bz)-amidite is an analogue of purine nucleoside. |
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V75714 | DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite | 325683-97-4 | DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite is an analogue of purine nucleoside. |
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