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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
Methyl 2-deoxy-3,5-di-O-toluoyl-D-ribofuranoside (地西他滨杂质2) V53257 Methyl 2-deoxy-3,5-di-O-toluoyl-D-ribofuranoside (decitabine impurity 2) 4330-34-1 Methyl 2-deoxy-3,5-di-O-toluoyl-D-ribofuranoside is an analogue of purine nucleoside.
Methyl 3’-O-benzyl xyloriboside V55459 Methyl 3'-O-benzyl xyloriboside 201014-45-1 Methyl 3'-O-benzyl xyloriboside is an analogue of purine nucleoside.
Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside V55479 Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside 636581-81-2 Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside is a ribofuranosyl nucleoside analog.
Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside V55330 Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside 55797-67-6 Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside is an analogue of purine nucleoside.
Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate V75769 Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate 70255-70-8 Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate is an analogue of purine nucleoside.
MMT-2'-O-Methyl adenosine (n-bz) CED phosphoramidite V84372 MMT-2'-O-Methyl adenosine (n-bz) CED phosphoramidite 2645354-88-5
N,N-Dimethyl-2′-O-methyladenosine V75660 N,N-Dimethyl-2′-O-methyladenosine 30891-53-3 N,N-Dimethyl-2′-O-methyladenosine is an analogue of purine nucleoside.
N,N-Dimethyl-2'-O-methylcytidine V55560 N,N-Dimethyl-2'-O-methylcytidine 34218-81-0 N,N-Dimethyl-2'-O-methylcytidine is an analogue of purine nucleoside.
N-(1-Oxopropyl)cytidine V55290 N-(1-Oxopropyl)cytidine 60107-04-2 N-(1-Oxopropyl)cytidine is a cytosine nucleoside analog.
N-(2-Phenoxyacetyl)adenosine V55901 N-(2-Phenoxyacetyl)adenosine 119824-65-6 N-(2-Phenoxyacetyl)adenosine is an adenine nucleoside analogue.
N-(2-Phenoxyacetyl)guanosine V51795 N-(2-Phenoxyacetyl)guanosine 119824-66-7 N-(2-Phenoxyacetyl)guanosine is an analog of guanosine.
N-(3-Methylbutyl)adenosine V75742 N-(3-Methylbutyl)adenosine 17659-78-8 N-(3-Methylbutyl)adenosine is an adenine nucleoside analog.
N-6-Methyl-2-deoxyadenosine ((2R,3S,5R)-2-(羟基甲基)-5-(6-(甲基氨基)-9H-嘌呤-9-基)四氢呋喃-3-醇) V55452 N-6-Methyl-2-deoxyadenosine ((2R,3S,5R)-2-(hydroxymethyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3-ol ) 2002-35-9 N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analog.
N-[(3-Methoxyphenyl)methyl]adenosine V75606 N-[(3-Methoxyphenyl)methyl]adenosine 101565-95-1 N-[(3-Methoxyphenyl)methyl]adenosine is an adenine nucleoside analogue.
N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine V55942 N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine 937205-20-4 N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine is a guanine nucleoside analogue.
N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine V55803 N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine 722505-71-7 N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine is an adenine nucleoside analog.
N-Acetyl-2′-deoxycytidine (N4-Acetyl-2'-deoxycytidine) V55699 N-Acetyl-2′-deoxycytidine (N4-Acetyl-2′-deoxycytidine) 32909-05-0 N-Acetyl-2′-deoxycytidine is an analogue of purine nucleoside.
N-Acetyladenosine V55960 N-Acetyladenosine 16265-37-5 N-Acetyladenosine is an adenine nucleoside analogue.
N-Benzoyl-2′-O-2-propyn-1-yladenosine V55838 N-Benzoyl-2′-O-2-propyn-1-yladenosine 210096-44-9 N-Benzoyl-2′-O-2-propyn-1-yladenosine is an adenine nucleoside analogue.
N-Benzoyl-3′-O-methyladenosine V55506 N-Benzoyl-3′-O-methyladenosine 85090-30-8 N-Benzoyl-3′-O-methyladenosine is an analogue of purine nucleoside.
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