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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxyadenosine V55414 N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxyadenosine 84138-86-3 N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxyadenosine is an analogue of purine nucleoside.
N-Benzoyl-5'-O-dmtr-2'-O-(2-methoxyethyl)-adenosine V55590 N-Benzoyl-5'-O-dmtr-2'-O-(2-methoxyethyl)-adenosine 251647-48-0 N-Benzoyl-5'-O-dmtr-2'-O-(2-methoxyethyl)-adenosine is an adenine nucleoside analogue.
N-Propargyladenosine V53317 N-Propargyladenosine 67005-97-4 N-Propargyladenosine is an adenine nucleoside analogue.
N1,N2-Dimethyl-2’-O-methylguanosine V55315 N1,N2-Dimethyl-2'-O-methylguanosine 2305416-05-9 N1,N2-Dimethyl-2'-O-methylguanosine is a guanine nucleoside analog.
N1-(1,1,1-Trifluoroethyl)pseudouridine V55894 N1-(1,1,1-Trifluoroethyl)pseudouridine 1613529-80-8 N1-(1,1,1-Trifluoroethyl)pseudouridine is an analogue of purine nucleoside.
N1-Allylpseudouridine V55364 N1-Allylpseudouridine 1613530-15-6 N1-Allylpseudouridine is an analogue of purine nucleoside.
N1-Benzyl pseudouridine V55835 N1-Benzyl pseudouridine 1613530-22-5 N1-Benzyl pseudouridine is an analogue of purine nucleoside.
N1-Cyclopropylmethylpseudouridine V55848 N1-Cyclopropylmethylpseudouridine 1613530-18-9 N1-Cyclopropylmethylpseudouridine is an analogue of purine nucleoside.
N1-Ethylpseudouridine V55857 N1-Ethylpseudouridine 1613529-72-8 N1-Ethylpseudouridine is an analogue of purine nucleoside.
N1-Methoxymethyl pseudouridine V55618 N1-Methoxymethyl pseudouridine 2131744-33-5 N1-Methoxymethyl pseudouridine is an analogue of purine nucleoside.
N1-Methyl ara-uridine V55682 N1-Methyl ara-uridine 17676-62-9 N1-Methyl ara-uridine is an analogue of purine nucleoside.
N1-Methyl-2’-deoxyinosine V55555 N1-Methyl-2'-deoxyinosine 72398-31-3 N1-Methyl-2'-deoxyinosine is an analogue of purine nucleoside.
N1-Methyl-5-methyl ara-uridine V55432 N1-Methyl-5-methyl ara-uridine 887113-66-8 N1-Methyl-5-methyl ara-uridine is an analogue of purine nucleoside.
N1-Methyl-arabinoadenosine V75690 N1-Methyl-arabinoadenosine 685880-77-7 N1-Methyl-arabinoadenosine is an analogue of purine nucleoside.
N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine V55426 N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine 1613530-24-7 N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine is an analogue of purine nucleoside.
N1-Propargylpseudouridine V55882 N1-Propargylpseudouridine 1464021-70-2 N1-Propargylpseudouridine (see GL102032) is an analogue of purine nucleoside.
N2,2'-O-Dimethylguanosine V55586 N2,2'-O-Dimethylguanosine 135023-21-1 N2,2'-O-Dimethylguanosine is an analogue of purine nucleoside.
N2,N2-Dimethylamino-6-deamino adenosine V55391 N2,N2-Dimethylamino-6-deamino adenosine 105208-35-3 N2,N2-Dimethylamino-6-deamino adenosine is an analogue of purine nucleoside.
N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine V55361 N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine 2095417-23-3 N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine is an analogue of purine nucleoside.
N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine V55870 N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2'-O-methylguanosine 2305416-07-1 N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2'-O-methylguanosine is a guanine nucleoside analogue.
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