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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
N2-Ethylguanosine V55541 N2-Ethylguanosine 77312-39-1 N2-Ethylguanosine is an analogue of purine nucleoside.
N2-iBu-2’,3’-bis-O-TBDMS guanosine V55851 N2-iBu-2',3'-bis-O-TBDMS guanosine 79974-70-2 N2-iBu-2',3'-bis-O-TBDMS guanosine is an analogue of purine nucleoside.
N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine V55512 N2-iBu-5'-O-DMTr-2'-O-hexadecanyl guanosine 2382942-31-4 N2-iBu-5'-O-DMTr-2'-O-hexadecanyl guanosine is an analogue of purine nucleoside.
N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite V55904 N2-iBu-5'-O-DMTr-2'-O-hexadecanyl guanosine 3'-CED phosphoramidite 2382942-32-5 N2-iBu-5'-O-DMTr-2'-O-hexadecanyl guanosine 3'-CED phosphoramidite is an analogue of purine nucleoside.
N2-iBu-5'-O-DMTr-2'-O-propargylguanosine-3'-CED-phosphoramidite V75567 N2-iBu-5'-O-DMTr-2'-O-propargylguanosine-3'-CED-phosphoramidite 171486-61-6 N2-iBu-5'-O-DMTr-2'-O-propargylguanosine-3'-CED-phosphoramidite is a guanine nucleoside analogue.
N2-iso-Butyroyl-2’-fluoro-2’-deoxyarabinoguanosine V55625 N2-iso-Butyroyl-2'-fluoro-2'-deoxyarabinoguanosine 308356-20-9 N2-iso-Butyroyl-2'-fluoro-2'-deoxyarabinoguanosine is an analogue of purine nucleoside.
N2-iso-Butyroyl-2’-O-propargylguanosine V55916 N2-iso-Butyroyl-2'-O-propargylguanosine 2095417-55-1 N2-iso-Butyroyl-2'-O-propargylguanosine is a guanine nucleoside analogue.
N2-iso-Butyroyl-3’-deoxy-3’-fluoro guanosine V55607 N2-iso-Butyroyl-3'-deoxy-3'-fluoro guanosine 2080404-20-0 N2-iso-Butyroyl-3'-deoxy-3'-fluoro guanosine is an analogue of purine nucleoside.
N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine V55789 N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine 256224-04-1 N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine is a guanine nucleoside analog.
N2-iso-Butyroyl-3’-O-methylguanosine V55877 N2-iso-Butyroyl-3'-O-methylguanosine 160107-07-3 N2-iso-Butyroyl-3'-O-methylguanosine is a guanine nucleoside analog.
N2-iso-Butyroyl-5’-O-(4,4’-dimethoxytrityl)-3’-O-methylguanosine V55599 N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylguanosine 103285-33-2 N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylguanosine is a guanine nucleoside analogue.
N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine V55860 N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine 2080404-19-7 N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is a guanine nucleoside analog.
N2-iso-Butyroyl-5’-O-DMT-3’-O-(methoxyethyl)guanosine V55858 N2-iso-Butyroyl-5'-O-DMT-3'-O-(methoxyethyl)guanosine 256224-05-2 N2-iso-Butyroyl-5'-O-DMT-3'-O-(methoxyethyl)guanosine is a guanine nucleoside analog.
N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine V55563 N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine 2243974-78-7 N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanine nucleoside analog.
N2-iso-Butyryl-2'-O-(2-methoxyethyl)guanosine V55648 N2-iso-Butyryl-2'-O-(2-methoxyethyl)guanosine 440327-50-4 N2-iso-Butyryl-2'-O-(2-methoxyethyl)guanosine is a guanine nucleoside analog.
N2-iso-Butyryl-8-azaguanosine V55533 N2-iso-Butyryl-8-azaguanosine 2328168-83-6 N2-iso-Butyryl-8-azagoanosine is an analogue of purine nucleoside.
N2-Isobutyryl-2'-O-methylguanosine (N-(9-((2R,3R,4R,5R)-4-羟基-5-(羟甲基)-3-甲氧基四氢呋喃-2-基)-6-氧代-6,9-二氢-3H-嘌呤-2-基)异丁酰胺) V55269 N2-Isobutyryl-2'-O-methylguanosine (N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl) -6-oxo-6,9-dihydro-3H-purin-2-yl)isobutylamide) 63264-29-9 N2-Isobutyryl-2'-O-methylguanosine (N2-IBU-2'-OME-RG) is an analogue of purine nucleoside.
N2-Phenoxyacetyl-3′,5′-O-(tetraisopropyldisiloxane-1,3-diyl)guanosine V55338 N2-Phenoxyacetyl-3′,5′-O-(tetraisopropyldisiloxane-1,3-diyl)guanosine 131474-72-1 N2-Phenoxyacetyl-3′,5′-O-(tetraisopropyldisiloxane-1,3-diyl)guanosine is a guanine nucleoside analogue.
N3-[(Tetrahydro-2-furanyl)methyl]uridine V55306 N3-[(Tetrahydro-2-furanyl)methyl]uridine 122666-26-6 N3-[(Tetrahydro-2-furanyl)methyl]uridine is a uridine analog.
N3-Allyluridine V55632 N3-Alyluridine 103951-13-9 N3-Allyluridine is a uridine analog.
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