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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
N3-Ethyl pseudouridine V55925 N3-Ethyl pseudouridine 2413585-37-0 N3-Ethyl pseudouridine is an analogue of purine nucleoside.
N3-Methyl-2’-O-(2-methoxyethyl)uridine V55798 N3-Methyl-2'-O-(2-methoxyethyl)uridine 2305416-12-8 N3-Methyl-2'-O-(2-methoxyethyl)uridine is a uridine analog.
N3-Methyl-2’-O-methyluridine V55492 N3-Methyl-2'-O-methyluridine 7103-27-7 N3-Methyl-2'-O-methyluridine is a uridine analog.
N3-Methyl-5-methyluridine V55639 N3-Methyl-5-methyluridine 3650-91-7 N3-Methyl-5-methyluridine is an analogue of purine nucleoside.
N4,N4-Dimethylarabinocytidine V55381 N4,N4-Dimethylarabinocytidine 82855-64-9 N4,N4-Dimethylarabinocytidine is a cytosine nucleoside analog.
N4,N4-Dimethylcytidine V55287 N4,N4-Dimethylcytidine 13007-43-7 N4,N4-Dimethylcytidine is a cytosine nucleoside analogue.
N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine V55816 N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine 121058-82-0 N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an analogue of purine nucleoside.
N4-Amino-2'-β-C-methylcytidine V75937 N4-Amino-2'-β-C-methylcytidine 622381-10-6 N4-Amino-2'-C-methylcytidine is an analogue of purine nucleoside.
N4-Benzo yl-5’-O-(4,4’-dimethoxytrityl)-aracytidine V55544 N4-Benzo yl-5'-O-(4,4'-dimethoxytrityl)-aracytidine 87418-76-6 N4-Benzo yl-5'-O-(4,4'-dimethoxytrityl)-aracytidine is an analogue of purine nucleoside.
N4-Benzoyl-2’-deoxy-2’,2’-diflurocytidine V55297 N4-Benzoyl-2'-deoxy-2',2'-diflurocytidine 142816-70-4 N4-Benzoyl-2'-deoxy-2',2'-diflurocytidine is an analogue of purine nucleoside.
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine V55677 N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 142808-43-3 N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine is an analogue of purine nucleoside.
N4-Benzoyl-2’-deoxy-5-iodocytidine V55663 N4-Benzoyl-2'-deoxy-5-iodocytidine 158042-39-8 N4-Benzoyl-2'-deoxy-5-iodocytidine is an analogue of purine nucleoside.
N4-Benzoyl-2’-O-(2-methoxyethyl)cytidine V55304 N4-Benzoyl-2'-O-(2-methoxyethyl)cytidine 2305416-18-4 N4-Benzoyl-2'-O-(2-methoxyethyl)cytidine is an analogue of purine nucleoside.
N4-Benzoyl-2'-O-methylcytidine (N4-Benzoyl-2'-O-methylcytidine) V75721 N4-Benzoyl-2'-O-methylcytidine (N4-Benzoyl-2'-O-methylcytidine) 52571-45-6 N4-Benzoyl-2'-O-methylcytidine is a cytosine nucleoside analogue.
N4-Benzoyl-3’-deoxycytidine V55979 N4-Benzoyl-3'-deoxycytidine 161110-00-5 N4-Benzoyl-3'-deoxycytidine is an analogue of purine nucleoside.
N4-Benzoyl-3’-O-methylcytidine V55300 N4-Benzoyl-3'-O-methylcytidine 85079-03-4 N4-Benzoyl-3'-O-methylcytidine is a cytosine nucleoside analogue.
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) V53098 N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) 67219-55-0 N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) may be utilized to prepare thioesters containing 3'-S-thiophosphate (3'-PS)-linked oligodeoxynucleotides are useful tools for probing enzymatic cleavage processes in DNA.
N4-Benzoyl-5'-O-(4,4-dimethoxytrityl)-3'-deoxy cytidine V75619 N4-Benzoyl-5'-O-(4,4-dimethoxytrityl)-3'-deoxy cytidine 86234-45-9 N4-Benzoyl-5'-O-(4,4-dimethoxytrityl)-3'-deoxy cytidine is an analogue of purine nucleoside.
N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine V75653 N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine 171486-51-4 N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an adenine nucleoside analogue.
N4-Benzoyl-5’-O-DMT-3’-O-(2-methoxyethyl)-5-methylcytidine V55326 N4-Benzoyl-5'-O-DMT-3'-O-(2-methoxyethyl)-5-methylcytidine 256223-98-0 N4-Benzoyl-5'-O-DMT-3'-O-(2-methoxyethyl)-5-methylcytidine is a cytosine nucleoside analogue.
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