Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V55635 | N4-Benzoyl-5'-O-DMT-5-methylcytidine | 160107-17-5 | N4-Benzoyl-5'-O-DMT-5-methylcytidine is a cytosine nucleoside analog. |
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V55868 | N4-Benzoyl-5'-O-DMTr-2'-O-(N3-trifluoroacetyl) aminopropyl cytidine | 1053243-01-8 | N4-Benzoyl-5'-O-DMTr-2'-O-(N3-trifluoroacetyl) aminopropyl cytidine is an analogue of purine nucleoside. |
|
V55559 | N4-Benzoyl-5-methyl-2'-O,4'-C-methylenecytidine | 206055-81-4 | N4-Benzoyl-5-methyl-2'-O,4'-C-methylenecytidine is a cytosine nucleoside analogue. |
|
V75657 | N4-Benzoyl-5-methylcytidine | 160107-15-3 | N4-Benzoyl-5-methylcytidine is an analogue of purine nucleoside. |
|
V55443 | N4-Benzoyl-7'-O-(4,4'-dimethoxytrityloxy)morpholinocytosine | 2304678-24-6 | N4-Benzoyl-7'-O-(4,4'-dimethoxytrityl oxy)morpholinocytosine is a cytosine nucleoside analogue. |
![N4-Benzoyl-7’-OH-N-trityl morpholino cytosine (N-[1-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide)](http://www.invivochem.com/upload/1124/hy-w357201.png)
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V55407 | N4-Benzoyl-7'-OH-N-trityl morpholino cytosine (N-[1-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4- yl]-benzamide) | 125515-31-3 | N4-Benzoyl-7'-OH-N-trityl morpholino cytosine is an analogue of purine nucleoside. |
|
V55865 | N4-Desmethyl wyosine | 59327-60-5 | N4-Desmethyl wyosine is an analogue of purine nucleoside. |
|
V55613 | N4-Desmethyl-N5-Methyl wyosine | 59327-63-8 | N4-Desmethyl-N5-Methyl wyosine is a guanine nucleoside analogue. |
|
V55312 | N4-Ethyl-2'-deoxycytidine | 70465-61-1 | N4-Ethyl-2'-deoxycytidine is an analogue of purine nucleoside. |
|
V55902 | N4-Methyl-2'-O-methyl-cytidine | 13048-95-8 | N4-Methyl-2'-O-methyl-cytidine is an analogue of purine nucleoside. |
|
V55826 | N4-Methylarabinocytidine | 13491-42-4 | N4-Methylarabinocytidine is a cytosine nucleoside analogue. |
|
V55279 | N4-Methylcytidine (N(4)-methylcytidine) | 10578-79-7 | N4-Methylcytidine (Nsc518744) is a cytosine nucleoside analog. |
|
V75949 | N6,N6-Dimethyl-2'-β-C-methyladenosine | 565450-77-3 | N6,N6-Dimethyl-2'-β-C-methyladenosine is an adenine nucleoside analog. |
|
V55373 | N6,N6-Dimethyl-3'-beta-C-methyl-adenosine | 565450-85-3 | N6,N6-Dimethyl-3'-beta-C-methyl-adenosine is an adenine nucleoside analogue. |
|
V55320 | N6,N6-Dimethyl-4'-thio-adenosine | 25795-69-1 | N6,N6-Dimethyl-4'-thio-adenosine is an analogue of purine nucleoside. |
|
V55335 | N6,N6-Dimethyl-xylo-adenosine | 669055-52-1 | N6,N6-Dimethyl-xylo-adenosine is an adenine nucleoside analogue. |
|
V55271 | N6-(2-Hydroxyethyl)adenosine | 4338-48-1 | N6-(2-Hydroxyethyl)adenosine is an analogue of purine nucleoside. |
|
V55673 | N6-(3-Methoxybenzyl)-2'-C-methyl adenosine | 2305415-85-2 | N6-(3-Methoxybenzyl)-2'-C-methyl adenosine is an adenine nucleoside analogue. |
|
V55543 | N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine | 2305415-78-3 | N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine is an adenine nucleoside analogue. |
|
V55672 | N6-(3-Trifluoromethylbenzyl)-3'-deoxyadenosine | 2305415-80-7 | N6-(3-Trifluoromethylbenzyl)-3'-deoxyadenosine is an analogue of purine nucleoside. |
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