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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
N6-(4-Methoxybenzyl)-2’-C-methyl adenosine V55341 N6-(4-Methoxybenzyl)-2'-C-methyl adenosine 2305415-98-7 N6-(4-Methoxybenzyl)-2'-C-methyl adenosine is an analogue of purine nucleoside.
N6-(4-Methoxybenzyl)adenosine V55970 N6-(4-Methoxybenzyl)adenosine 23666-24-2 N6-(4-Methoxybenzyl)adenosine is an adenine nucleoside analog.
N6-Aminoadenosine V56022 N6-Aminoadenosine 5746-27-0 N6-Aminoadenosine is an adenine nucleoside analog.
N6-Benzoyl-2',3'-isopropylidene adenosine V55823 N6-Benzoyl-2',3'-isopropylidene adenosine 39947-04-1 N6-Benzoyl-2',3'-isopropylidene adenosine is an adenine nucleoside analogue.
N6-Benzoyl-2'-chloro-2'-deoxyadenosine V75639 N6-Benzoyl-2'-chloro-2'-deoxyadenosine 2095417-58-4 N6-Benzoyl-2'-chloro-2'-deoxyadenosine is an analogue of purine nucleoside.
N6-Benzoyl-2'-chloro-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine V75682 N6-Benzoyl-2'-chloro-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine 2243079-24-3 N6-Benzoyl-2'-chloro-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is an analogue of purine nucleoside.
N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine V55517 N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine 144924-99-2 N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine is an adenine nucleoside analogue.
N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine V55460 N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine 333335-93-6 N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is an analogue of purine nucleoside.
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine V55488 N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine 1214886-17-5 N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine is an adenine nucleoside analogue.
N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine V55430 N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine 170871-87-1 N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is an analogue of purine nucleoside.
N6-Benzoyl-3'-fluoro-2',3'-dideoxyadenosine V55683 N6-Benzoyl-3'-fluoro-2',3'-dideoxyadenosine 122712-71-4 N6-Benzoyl-3'-fluoro-2',3'-dideoxyadenosine is an analogue of purine nucleoside.
N6-Benzoyl-3’-O-(2-methoxyethyl)adenosine V55367 N6-Benzoyl-3'-O-(2-methoxyethyl)adenosine 256223-99-1 N6-Benzoyl-3'-O-(2-methoxyethyl)adenosine is an analogue of purine nucleoside.
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine V55707 N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine 64325-78-6 N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine can be used as an intermediate.
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(2-methoxyethyl)adenosine V55380 N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(2-methoxyethyl)adenosine 256224-00-7 N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(2-methoxyethyl)adenosine is an analogue of purine nucleoside.
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite V55285 N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite 179479-02-8 N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenine nucleoside analogue.
N6-Benzoyl-7'-O-DMT-morpholino adenine V55310 N6-Benzoyl-7'-O-DMT-morpholino adenine 2243974-77-6 N6-Benzoyl-7'-O-DMT-morpholino adenine is an adenine nucleoside analogue.
N6-Benzoyl-7’-OH-morpholino adenine (N6-Benzoyl-7'-OH-Morpholino adenosine) V55666 N6-Benzoyl-7'-OH-morpholino adenine (N6-Benzoyl-7'-OH-Morpholino adenosine) 139290-78-1 N6-Benzoyl-7'-OH-morpholino adenine is an analogue of purine nucleoside.
N6-Benzoyl-7’-OH-N-trityl morpholino adenine (N-[9-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-9H-purin-6-yl]-benzamide) V55319 N6-Benzoyl-7'-OH-N-trityl morpholino adenine (N-[9-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-9H-purin-6-yl]-benzamide) 956139-16-5 N6-Benzoyl-7'-OH-N-trityl morpholino adenine is an analogue of purine nucleoside.
N6-Benzoyl-9-β-D-arabinofuranosyladenine V75935 N6-Benzoyl-9-β-D-arabinofuranosyladenine 79896-97-2 N6-Benzoyl-9-β-D-arabinofuranosyladenine is an adenine nucleoside analog.
N6-Benzoyl-9-β-D-arabinofuranosyladenine hydrate V84550 N6-Benzoyl-9-β-D-arabinofuranosyladenine hydrate
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