Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V55913 | N6-Benzyl-2'-C-methyladenosine | 849241-79-8 | N6-Benzyl-2'-C-methyladenosine is an adenine nucleoside analog. |
|
V55641 | N6-Bz-5'-O-DMTr-2'-O-hexadecanyl adenosine | 2382942-34-7 | N6-Bz-5'-O-DMTr-2'-O-hexadecanyl adenosine is an analogue of purine nucleoside. |
|
V75569 | N6-Bz-5'-O-DMTr-2'-O-hexadecanyl adenosine 3'-CED phosphoramidite | 2382942-35-8 | N6-Bz-5'-O-DMTr-2'-O-hexadecanyl adenosine 3'-CED phosphoramidite is an analogue of purine nucleoside. |
|
V56009 | N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite | 207347-42-0 | N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analogue. |
|
V55301 | N6-Dimethylamino methylidene-2'-deoxyisoguanosine | 146196-17-0 | N6-Dimethylamino methylidene-2'-deoxyisoguanosine is an analogue of purine nucleoside. |
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V55589 | N6-Dimethylaminomethylidene isoguanosine | 156706-72-8 | N6-Dimethylaminomethylidene isoguanosine is an analogue of purine nucleoside. |
|
V55893 | N6-Dimethyldeoxyadenosine | 35665-58-8 | N6-Dimethyldeoxyadenosine is an analogue of purine nucleoside. |
|
V75568 | N6-Ethyl-2'-C-methyladenosine | 714250-18-7 | N6-Ethyl-2'-C-methyladenosine is an analogue of purine nucleoside. |
|
V55662 | N6-Ethyl-2'-deoxyadenosine | 136050-93-6 | N6-Ethyl-2'-deoxyadenosine is an analogue of purine nucleoside. |
|
V55963 | N6-Ethyl-2'-O-methyladenosine | 157309-11-0 | N6-Ethyl-2'-O-methyladenosine is an analogue of purine nucleoside. |
|
V55321 | N6-Furfuryl-2'-C-methyladenosine | 1042976-44-2 | N6-Furfuryl-2'-C-methyladenosine is an analogue of purine nucleoside. |
|
V75638 | N6-Furfuryl-2-aminoadenosine | 26783-39-1 | N6-Furfuryl-2-aminoadenosine is an analogue of purine nucleoside. |
|
V75668 | N6-iso-Propyl-2'-O-methyladenosine | 2803878-84-2 | N6-iso-Propyl-2'-O-methyladenosine is an analogue of purine nucleoside. |
|
V55489 | N6-iso-Propyladenosine | 17270-23-4 | N6-iso-Propyladenosine is an analogue of purine nucleoside. |
|
V55396 | N6-Isopentenyl-2'-C-methyladenosine | 2305416-13-9 | N6-Isopentenyl-2'-C-methyladenosine is an adenine nucleoside analog. |
|
V55702 | N6-Isopentenyl-2'-deoxy adenosine, 2'-deoxy riboprine | 25775-85-3 | N6-Isopentenyl-2'-deoxy adenosine, 2'-deoxy riboprine is an analogue of purine nucleoside. |
|
V75523 | N6-Methyl-2'-β-C-methyladenosine | 565450-76-2 | N6-Methyl-2'-β-C-methyladenosine is an adenine nucleoside analog. |
|
V55439 | N6-Methyl-2-methyl thioadenosine | 6741-71-5 | N6-Methyl-2-methyl thioadenosine is an analogue of purine nucleoside. |
|
V55305 | N6-Methyl-4'-thio-adenosine | 900810-24-4 | N6-Methyl-4'-thio-adenosine is an analogue of purine nucleoside. |
|
V53284 | N6-Methyl-dA phosphoramidite | 105931-58-6 | N6-Methyl-dA phosphoramidite may be utilized to prepare oligodeoxyribonucleotides. |
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