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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
2′,3′-Dideoxy-3′-fluoroadenosine V75667 2′,3′-Dideoxy-3′-fluoroadenosine 87418-35-7 2′,3′-Dideoxy-3′-fluoroadenosine is an analogue of purine nucleoside.
2’,3’-Dideoxy-3’-fluorocytidine V55272 2',3'-Dideoxy-3'-fluorocytidine 51246-79-8 2',3'-Dideoxy-3'-fluorocytidine is an analogue of purine nucleoside.
2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine) V75574 2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine) 41107-56-6 2′,3′-Dideoxy-3′-fluorouridine is an analogue of purine nucleoside.
2’,3’-Dideoxy-5-fluorocytidine V55935 2',3'-Dideoxy-5-fluorocytidine 107036-62-4 2',3'-Dideoxy-5-fluorocytidine is an analogue of purine nucleoside.
2′,3′-Dideoxy-5-fluorouridine V55842 2′,3′-Dideoxy-5-fluorouridine 15379-30-3 2′,3′-Dideoxy-5-fluorouridine is an analogue of purine nucleoside.
2',3'-Dideoxyuridine V56017 2',3'-Dideoxyuridine 5983-09-5 2',3'-Dideoxyuridine is an analogue of purine nucleoside.
2',3'-Isopropylidene-5-hydroxyuridine V75661 2',3'-Isopropylidene-5-hydroxyuridine 20406-82-0 2',3'-Isopropylidene-5-hydroxyuridine is an analogue of purine nucleoside.
2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine V55291 2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine 89845-82-9 2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine is an analogue of purine nucleoside.
2',3'-O-Isopropylideneadenosine (2',3'-异亚丙基腺苷) V55274 2',3'-O-Isopropylideneadenosine 362-75-4 2',3'-O-Isopropylideneadenosine is an adenine nucleoside analogue.
2′,3′-O-Isopropylideneisocytidine V75626 2′,3′-O-Isopropylideneisocytidine 5975-05-3 2′,3′-O-Isopropylideneisocytidine is an analogue of purine nucleoside.
2',3,5'-Tri-O-benzoyl-4'-thiouridine V75521 2',3,5'-Tri-O-benzoyl-4'-thiouridine 2072145-30-1 2',3',5'-Tri-O-benzoyl-4'-thiouridine is an analogue of purine nucleoside.
2',5'-Bis-O-(triphenylMethyl)uridine V55309 2',5'-Bis-O-(triphenylMethyl)uridine 6554-11-6 2',5'-Bis-O-(triphenylMethyl)uridine is a uridine analog.
2′,5′-Dideoxy-5′-iodouridine V55919 2′,5′-Dideoxy-5′-iodouridine 58510-66-0 2′,5′-Dideoxy-5′-iodouridine is an analogue of purine nucleoside.
2’,5’-Dideoxyuridine V55540 2',5'-Dideoxyuridine 35959-50-3 2',5'-Dideoxyuridine is an analogue of purine nucleoside.
2',5-Difluoro-2'-deoxy-1-arabinosyluracil (1-(2-脱氧-2-氟-BETA-D-阿拉伯呋喃糖基)-5-氟-2,4(1H,3H)-嘧啶二酮) V55879 2',5-Difluoro-2'-deoxy-1-arabinosyluracil (1-(2-deoxy-2-fluoro-BETA-D-arabinofuranosyl)-5-fluoro-2,4(1H,3H)- pyrimidinedione) 69123-95-1 5-Fluoro-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (2 ',5-difluoro-2'-deoxy-1-arabinosyluracil) is a uridine analog.
2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine V55358 2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine 158665-47-5 2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine is an analogue of purine nucleoside.
2’-Amino-2’-deoxy-5-fluoro-arabinouridine V55552 2'-Amino-2'-deoxy-5-fluoro-arabinouridine 2305415-81-8 2'-Amino-2'-deoxy-5-fluoro-arabinouridine is an analogue of purine nucleoside.
2’-Amino-2’-deoxy-5-methyl uridine V55859 2'-Amino-2'-deoxy-5-methyl uridine 869729-38-4 2'-Amino-2'-deoxy-5-methyl uridine is an analogue of purine nucleoside.
2’-Amino-2’-deoxy-5-methylcytidine V55606 2'-Amino-2'-deoxy-5-methylcytidine 869729-45-3 2'-Amino-2'-deoxy-5-methylcytidine is an analogue of purine nucleoside.
2'-Amino-2'-deoxy-β-D-arabino-5-methyl uridine V75551 2'-Amino-2'-deoxy-β-D-arabino-5-methyl uridine 135304-48-2 2'-Amino-2'-deoxy-β-D-arabino-5-methyl uridine is an analogue of purine nucleoside.
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