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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
2'-Amino-2'-deoxy-β-D-arabinouridine V75608 2'-Amino-2'-deoxy-β-D-arabinouridine 68115-81-1 2'-Amino-2'-deoxy-β-D-arabinouridine is an analogue of purine nucleoside.
2′-Amino-2′-deoxycytidine V75731 2′-Amino-2′-deoxycytidine 26889-42-9 2′-Amino-2′-deoxycytidine is an analogue of purine nucleoside.
2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine V55930 2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine 174221-86-4 2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is an analogue of purine nucleoside.
2’-Azido-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine V56004 2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine 2095417-08-4 2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine is an analogue of purine nucleoside.
2'-Azido-2'-deoxy-5-methyl cytidine V75627 2'-Azido-2'-deoxy-5-methyl cytidine 2095417-75-5 2'-Azido-2'-deoxy-5-methyl cytidine is an analogue of purine nucleoside.
2′-Azido-2′-deoxy-5-methyluridine V55883 2′-Azido-2′-deoxy-5-methyluridine 97748-75-9 2′-Azido-2′-deoxy-5-methyluridine is an analogue of purine nucleoside.
2’-Azido-2’-deoxycytidine V55532 2'-Azido-2'-deoxycytidine 51034-68-5 2'-Azido-2'-deoxycytidine is an analogue of purine nucleoside.
2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine V55602 2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine 177980-10-8 2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is an analogue of purine nucleoside.
2’-Beta-C-Ethynyl inosine V55885 2'-Beta-C-Ethynyl inosine 2183487-92-3 2'-Beta-C-Ethynyl inosine is an analogue of purine nucleoside.
2’-beta-C-Methyl-4-thiouridine V55983 2'-beta-C-Methyl-4-thiouridine 1106032-94-3 2'-beta-C-Methyl-4-thiouridine is an analogue of purine nucleoside.
2’-Bromo-2’-deoxy-5-fluorouridine V55923 2'-Bromo-2'-deoxy-5-fluorouridine 32791-82-5 2'-Bromo-2'-deoxy-5-fluorouridine is an analogue of purine nucleoside.
2’-Bromo-2’-deoxy-5-methyluridine V55397 2'-Bromo-2'-deoxy-5-methyluridine 95585-76-5 2'-Bromo-2'-deoxy-5-methyluridine is an analogue of purine nucleoside.
2′-Bromo-2′-deoxyuridine (2'-Bromo-2'-deoxy-D-uridine) V55646 2′-Bromo-2′-deoxyuridine (2'-Bromo-2'-deoxy-D-uridine) 4753-02-0 2′-Bromo-2′-deoxyuridine is an analogue of purine nucleoside.
2'-C-Ethynyluridine (2'-C-乙炔基尿苷) V55451 2'-C-Ethynyluridine (2'-C-ethynyluridine) 188413-98-1 2'-C-Ethynyluridine is an analogue of purine nucleoside.
2′-C-Methyl-6-O-methylinosine V51314 2′-C-Methyl-6-O-methylinosine 565450-78-4 2′-C-Methyl-6-O-methylinosine is an analog of hypoxanthine
2'-C-Methylguanosine (2'-C-beta-Methylguanosine) V55831 2'-C-Methylguanosine (2'-C-beta-Methylguanosine) 374750-30-8 2'-C-Methylguanosine (2'-C-beta-Methylguanosine) is a guanine nucleoside analogue.
2'-C-methyluridine (1-(2-C-甲基-β-D-呋喃核糖基)尿嘧啶) V55273 2'-C-methyluridine (1-(2-C-methyl-β-D-ribofuranosyl)uracil) 31448-54-1 2'-C-methyluridine is a uridine analog.
2'-C-β-Methyl-4-deoxyuridine V75699 2'-C-β-Methyl-4-deoxyuridine 1106032-88-5 2'-C-β-Methyl-4-deoxyuridine is an analogue of purine nucleoside.
2'-Chloro-2'-deoxyadenosine V75575 2'-Chloro-2'-deoxyadenosine 2627-62-5 2'-Chloro-2'-deoxyadenosine is an analogue of purine nucleoside.
2′-Chloro-2′-deoxyuridine (2'-氯-2'-脱氧尿苷) V55889 2′-Chloro-2′-deoxyuridine 4753-04-2 2′-Chloro-2′-deoxyuridine is an analogue of purine nucleoside.
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