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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite/Analog related products

Structure Cat No. Product Name CAS No. Product Description
2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine V55496 2'-Deoxy-2'-fluoro-6-S-Methyl-6-thio-ara-guanosine 109304-11-2 2'-Deoxy-2'-fluoro-6-S-Methyl-6-thio-ara-guanosine is an analogue of purine nucleoside.
2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-arabino-inosine V55473 2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine 109304-12-3 2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine is an analogue of purine nucleoside.
2’-Deoxy-2’-fluoro-alpha-D-arabinoguanosine V55920 2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine 2072145-29-8 2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-arabino-tubercidine (T 70179) V75591 2'-Deoxy-2'-fluoro-arabino-tubercidine (T 70179) 169516-61-4 2'-Deoxy-2'-fluoro-arabino-tubercidine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-bD-arabinocytidine (4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one) V75679 2'-Deoxy-2'-fluoro-bD-arabinocytidine (4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one) 56632-83-8 2'-Deoxy-2'-fluoro-bD-arabinocytidine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-bD-arabinocytidine hydrochloride V75642 2'-Deoxy-2'-fluoro-bD-arabinocytidine hydrochloride 25183-22-6 2'-Deoxy-2'-fluoro-bD-arabinocytidine( HCl) is a cytosine nucleoside analog.
2′-Deoxy-2′-fluoro-N-methyladenosine V55611 2′-Deoxy-2′-fluoro-N-methyladenosine 134444-58-9 2′-Deoxy-2′-fluoro-N-methyladenosine is an analogue of purine nucleoside.
2’-Deoxy-2’-fluoro-N1-methyl inosine V55795 2'-Deoxy-2'-fluoro-N1-methyl inosine 2376610-64-7 2'-Deoxy-2'-fluoro-N1-methyl inosine is an analogue of purine nucleoside.
2’-Deoxy-2’-fluoro-N3-(2S)-(2-amino-3-carbonyl] propyl-beta-D-arabinouridine V55444 2'-Deoxy-2'-fluoro-N3-(2S)-(2-amino-3-carbonyl] propyl-beta-D-arabinouridine 2072145-25-4 2'-Deoxy-2'-fluoro-N3-(2S)-(2-amino-3-carbonyl] propyl-beta-D-arabinouridine is an analogue of purine nucleoside.
2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine V55918 2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine 2072145-77-6 2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine is an analogue of purine nucleoside.
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)-beta-D-arabinouridine V55454 2'-Deoxy-2'-fluoro-N3-(n-dodecyl)-beta-D-arabinouridine 2072145-43-6 2'-Deoxy-2'-fluoro-N3-(n-dodecyl)-beta-D-arabinouridine is a uridine analog.
2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]-beta-D-arabinouridine V55691 2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]-beta-D-arabinouridine 2072145-51-6 2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]-beta-D-arabinouridine is an analogue of purine nucleoside.
2’-Deoxy-2’-fluoro-N3-[(pyrid-4-yl)methyl]-beta-D-arabinouridine V55671 2'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]-beta-D-arabinouridine 2072145-47-0 2'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]-beta-D-arabinouridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine V55866 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine 182495-81-4 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-β-D-arabino-2-thiouridine V75646 2'-Deoxy-2'-fluoro-β-D-arabino-2-thiouridine 1006872-85-0 2'-Deoxy-2'-fluoro-β-D-arabino-2-thiouridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-β-D-arabino-6-azauridine V75630 2'-Deoxy-2'-fluoro-β-D-arabino-6-azauridine 908129-24-8 2'-Deoxy-2'-fluoro-β-D-arabino-6-azauridine is an analogue of purine nucleoside.
2′-Deoxy-2′-fluoroadenosine V52924 2′-Deoxy-2′-fluoroadenosine 64183-27-3 2'-Deoxy-2'-fluoroadenosine may be utilized to prepare 2'-deoxy-2'-fluoro modified oligonucleotides that hybridize to RNA.
2'-Deoxy-2'-fluoroarabino inosine V75736 2'-Deoxy-2'-fluoroarabino inosine 98983-40-5 2'-Deoxy-2'-fluoroarabino inosine is an analogue of purine nucleoside.
2’-Deoxy-2’-fluoroarabino-O6-methyl inosine V55950 2'-Deoxy-2'-fluoroarabino-O6-methyl inosine 109304-06-5 2'-Deoxy-2'-fluoroarabino-O6-methyl inosine is an analogue of purine nucleoside.
2’-Deoxy-2’-fluoroinosine (2'-Fluoro-2'-deoxyinosine) V55643 2'-Deoxy-2'-fluoroinosine (2'-Fluoro-2'-deoxyinosine) 80049-87-2 2'-Deoxy-2'-fluoroinosine is an analogue of purine nucleoside.
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