White blood cells (leukocytes), which are a subset of cytokines (secreted proteins and signaling molecules), were the first to be observed to express interleukins. Interleukins are crucial for the immune system's proper operation, and there have been rare cases of their deficiency that have all been associated with autoimmune disorders or immune deficiencies. Helper CD4 T lymphocytes, along with monocytes, macrophages, and endothelial cells, produce the majority of interleukins. They support the growth and differentiation of hematopoietic cells, including T and B lymphocytes. The development of spatial memories in mice has also been linked to interleukin receptors on astrocytes in the hippocampus.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V75049 | Varokibart | 2643349-04-4 | Varokibart (TEV-53275) is a human IgG4λ antibody targeting IL-5. |
|
V84568 | VEGFR-2-IN-40 | ||
|
V101429 | Vimekofusp | Vimekofusp is an anti-IL10RA/IL10RB monoclonal antibody. | |
|
V75048 | Temtokibart | 2733581-99-0 | Vopikitug is an IgG1-kappa, human monoclonal antibody (mAb) against IL-2RA (interleukin 2 receptor alpha subunit, IL-2RA, TAC, p55, CD25). |
|
V71703 | Y13g | 2766380-73-6 | Y13g is a potent inhibitor of AChE and IL-6. |
|
V75007 | β-Interleukin II (44-56) | 309247-07-2 | β-Interleukin II (44-56) is the 44-56 fragment of the β-Interleukin II polypeptide. |
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