Size | Price | Stock | Qty |
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5mg |
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10mg |
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25mg |
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50mg |
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100mg |
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Other Sizes |
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Purity: ≥98%
(R)-Oxiracetam is the R-isomer of oxiracetam (also known as ISF 2522), which is a widely used nootropic drug and improves memory and learning in patients with cognitive impairments. Oxiracetam (50 mg/kg i.p.) improves avoidance acquisition in BALB/c mice. Oxiracetam (100 mg/kg i.p.) reduces the scopolamine-induced amnesic effect and decrease in acetylcholine level in the cortex and hippocampus. Oxiracetam pretreatment (30 mg/kg) prevents social recognition deficits produced with trimethyltin in rats.
ln Vitro |
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ln Vivo |
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Animal Protocol |
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References |
Arch Int Pharmacodyn Ther.1985 May;275(1):86-92;Pharmacol Biochem Behav.1987 Jul;27(3):491-5.
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Molecular Formula |
C6H10N2O3
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Molecular Weight |
158.16
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CAS # |
68252-28-8
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Related CAS # |
(S)-Oxiracetam;88929-35-5;Oxiracetam;62613-82-5
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Appearance |
Typically exists as solids (or liquids in special cases) at room temperature
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SMILES |
O=C(N)CN1C(C[C@@H](O)C1)=O
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InChi Key |
IHLAQQPQKRMGSS-UHFFFAOYSA-N
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InChi Code |
InChI=1S/C6H10N2O3/c7-5(10)3-8-2-4(9)1-6(8)11/h4,9H,1-3H2,(H2,7,10)
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Chemical Name |
4-Hydroxy-2-oxopyrrolidine-N-acetamide
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Synonyms |
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HS Tariff Code |
2934.99.9001
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
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Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
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Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (632.27 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
 (Please use freshly prepared in vivo formulations for optimal results.) |
Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 6.3227 mL | 31.6136 mL | 63.2271 mL | |
5 mM | 1.2645 mL | 6.3227 mL | 12.6454 mL | |
10 mM | 0.6323 mL | 3.1614 mL | 6.3227 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.