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Microtubule(Tubulin)

Microtubule(Tubulin)

Microtubules are a component of the cytoskeleton, found throughout the cytoplasm.These highly dynamic tubular tubulin polymers have an average length of 25 m and a maximum growth length of 50 micrometers. A microtubule has an inner diameter of 12 nm and an outer diameter of about 24 nm. Alpha and beta tubulin combine to form a dimer, which is then polymerized to form microtubules, which are found in eukaryotic cells. One of many members of a small family of globular proteins is tubulin.The alpha-, beta-, gamma-, delta-, and epsilon-tubulins are among the five distinct families that make up the tubulin superfamily, and a sixth family is only found in kinetoplastid protozoa. The proteins that make up microtubules, -tubulin and -tubulin, are the most prevalent members of the tubulin family. Microtubules play a crucial role in many cellular processes. They assist in keeping the cell's structure intact.

Microtubule(Tubulin) related products

Structure Cat No. Product Name CAS No. Product Description
(S)-Alyssin V94644 (S)-Alyssin 167963-04-4 (S)-Alyssin is an isomer of alyssin.
10-去乙酰紫杉醇 V29322 10-Deacetyltaxol 78432-77-6 10-Deacetyltaxol (also called 10-Deacetylpaclitaxel), the 10-deacetylated form of paclitaxel, is a taxane analogue andimpurity of Paclitaxel extracted from Taxus wallichiana Zucc with anticancer activities.
2'-O-TBDMS-Paclitaxel V100448 2'-O-TBDMS-Paclitaxel 114655-02-6 2'-O-TBDMS-Paclitaxel is a paclitaxel derivative in which the 2'-OH group is substituted and protected with tert-butyldimethylsilane (TBDMS) ether.
3,4',5-Trismethoxybenzophenone V84553 3,4',5-Trismethoxybenzophenone 94709-12-3
3-Demethylthiocolchicine V96697 3-Demethylthiocolchicine 87424-25-7 3-Demethylthiocolchicine is a colchicine analog with broad-spectrum antitumor activity.
7,10-o-ditroc 多西他赛，7,10-o-ditroc 多烯紫杉醇 V92647 7,10-o-ditroc docetaxel 114915-14-9 7,10-o-ditroc docetaxel is a taxol analog and a microtubule depolymerization inhibitor that works by binding to stabilized microtubules.
7-表紫杉醇 V34036 7-epi-Taxol 105454-04-4 7-epi-Taxol, the epimer of taxol (paclitaxel), is a major and active metabolite of taxol isolated fromTaxus brevifolia with comparable anticancr/antitubulin activityto that of paclitaxek/taxol.
ABT-751 hydrochloride V88427 ABT-751 hydrochloride 141450-48-8 ABT-751 (E7010) hydrochloride is a novel, highly orally bioavailable sulfonamide antimitotic compound and tubulin binding agent.
ADC Control Human IgG1-vcMMAE V88374 ADC Control Human IgG1-vcMMAE ADC Control Human IgG1-vcMMAE is a human monoclonal antibody, which is the isotype control of ADC human IgG1-vcMMAE and can inhibit tubulin polymerization.
ADC Control Human IgG1-vcMMAF V88371 ADC Control Human IgG1-vcMMAF ADC Control Human IgG1-vcMMAF is a human monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAF and can inhibit tubulin polymerization.
AM-9022 V84913 AM-9022 2446872-46-2 AM-9022 is an orally active, potent and selective KIF18A inhibitor that can be used in cancer research.
Amiprofos methyl (BAY-NTN 6867) V35084 Amiprofos methyl (BAY-NTN 6867) 36001-88-4 Amiprofos methyl (BAY-NTN 6867) is a phosphate amide herbicide.
Anti-α-Tubulin Antibody, AF555 conjugate V78086 Anti-α-Tubulin Antibody, AF555 conjugate Anti-α-Tubulin Antibody, AF555 conjugate is a conjugate of mouse anti-α-tubulin monoclonal antibody (mAb) and the red fluorescent dye Alexa Fluor 555, which may be utilized to detect tubulin (Ex/Em: 554/567 nm).
Anticancer agent 139 V77986 Anticancer agent 139 Anticancer agent 139 (Compound 6h) has potent anti-cancer activity.
Anticancer agent 98 V34998 Anticancer agent 98 2857070-72-3 Anticancer agent 98 (compound 12k) is a tubulin polymerization inhibitor (Kd=16.9 μM).
Antiproliferative agent-14 V34829 Antiproliferative agent-14 1885900-35-5 antiproliferation agent-14 (compound 3b) is a potent inhibitor of tubulin polymerization with IC50 of 3.41 μM.
Antiproliferative agent-23 V78056 Antiproliferative agent-23 antiproliferation agent-23 is a microtubule destabilizing agent (MDA) that effectively interferes with the tubulin-microtubule system.
Antiproliferative agent-30 V55250 Antiproliferative agent-30 2713553-88-7 antiproliferation agent-30 (Compound 8g) inhibits tubulin assembly and inhibits FLT3 and Abl1.
Antitubulin agent 1 V79807 Antitubulin agent 1 Antitubulin agents-1 is an antitubulin agent that induces disruption of microtubules (Microtubule/Tubulin) and increases α-tubulin acetylation.
Antitumor agent-138 V83574 Antitumor agent-138 2975168-22-8
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