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Nucleoside Antimetabolite(Analog)

Nucleoside Antimetabolite(Analog)

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite(Analog) related products

Structure Cat No. Product Name CAS No. Product Description
N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine V80881 N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytosine nucleoside analogue.
N6-Acetyloxymethyladenosine V80548 N6-Acetyloxymethyladenosine N6-Acetyloxymethyladenosine is an adenine nucleoside analog.
N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine V80883 N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine is an analogue of purine nucleoside.
N6-Ethyl-2'-beta-C-ethynyl adenosine V80201 N6-Ethyl-2'-beta-C-ethynyl adenosine N6-Ethyl-2'-beta-C-ethynyl adenosine is an analogue of purine nucleoside.
N6-Ethyl-4'-thio-adenosine V80264 N6-Ethyl-4'-thio-adenosine N6-Ethyl-4'-thio-adenosine is an analogue of purine nucleoside.
N6-Methyl-2'-beta-C-ethynyl adenosine V80235 N6-Methyl-2'-beta-C-ethynyl adenosine N6-Methyl-2'-beta-C-ethynyl adenosine is an analogue of purine nucleoside.
N6-Methyl-2'-O-(2-methoxyethyl) adenosine V80469 N6-Methyl-2'-O-(2-methoxyethyl) adenosine N6-Methyl-2'-O-(2-methoxyethyl) adenosine is an analogue of purine nucleoside.
N6-Methyl-3'-O-(2-methoxyethyl) adenosine V80470 N6-Methyl-3'-O-(2-methoxyethyl) adenosine N6-Methyl-3'-O-(2-methoxyethyl) adenosine is an analogue of purine nucleoside.
N6-Pivaloyloxymethyladenosine V80114 N6-Pivaloyloxymethyladenosine N6-Pivaloyloxymethyladenosine is an analogue of purine nucleoside.
N7-Methyl-2'-beta-C-methyl guanosine V80607 N7-Methyl-2'-beta-C-methyl guanosine N7-Methyl-2'-beta-C-methyl guanosine is an analogue of purine nucleoside.
N7-Methyl-2'-deoxy-2'-fluoroarabinoguanosine V80751 N7-Methyl-2'-deoxy-2'-fluoroarabinoguanosine N7-Methyl-2'-deoxy-2'-fluoroarabinoguanosine is an analogue of purine nucleoside.
N7-Methyl-2'-O-(2-methoxyethyl) guanosine V80466 N7-Methyl-2'-O-(2-methoxyethyl) guanosine N7-Methyl-2'-O-(2-methoxyethyl) guanosine is an analogue of purine nucleoside.
Rev 2'-O-MOE-5MeC(Bz)-5'-amidite V77739 Rev 2'-O-MOE-5MeC(Bz)-5'-amidite Rev 2'-O-MOE-5MeC(Bz)-5'-amidite is an analogue of purine nucleoside.
Rev 2'-O-MOE-A(Bz)-5'-amidite V81288 Rev 2'-O-MOE-A(Bz)-5'-amidite Rev 2'-O-MOE-A(Bz)-5'-amidite is an analogue of purine nucleoside.
Rev 2'-O-MOE-C(Bz)-5'-amidite V77802 Rev 2'-O-MOE-C(Bz)-5'-amidite Rev 2'-O-MOE-C(Bz)-5'-amidite is an analogue of purine nucleoside.
Rev dC(Bz)-5'-amidite V81289 Rev dC(Bz)-5'-amidite Rev dC(Bz)-5'-amidite is an analogue of purine nucleoside.
RX-3117 V7645 RX-3117 865838-26-2 RX-3117 (TV-1360; RX3117; fluorocyclopentenylcytosine), acytidine analog, is an orally bioavailable and potent DNA synthesis inhibitor with potential anticanceractivity.
Sapacitabine (CS682; CYC682) V14006 Sapacitabine (CS682; CYC682) 151823-14-2 Sapacitabine(CS-682; CYC-682) is a highly potent and orally bioactive pyrimidine analogue prodrug with potential anticancer activity.
Triazavirin sodium hydrate (TZV, Riamilovir) V2188 Triazavirin sodium hydrate (TZV, Riamilovir) 928659-17-0 :Triazavirin sodium hydrate (TZV, Riamilovir), a nucleoside analogue of nucleic acid, is a broad-spectrum and potent antiviral agent.
Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester V77851 Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester is an analogue of purine nucleoside.
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