|
V75417
|
Ogremorphin (OGM; GPR68-IN-1)
|
352563-21-4 |
Ogremorphin (GPR68-IN-1) is a potent GPR68 inhibitor (antagonist) with EC50 of 170 nM. |
|
V70306
|
PSN 375963 hydrochloride
|
1781834-82-9 |
PSN 375963 HCl is a potent GPR119 agonist/activator with EC50 of 8.4 and 7.9 μM in humans and mice, respectively. |
|
V76546
|
RTI-13951-33 hydrochloride
|
|
RTI-13951-33 HCl is a specific, BBB (blood-brain barrier) permeable (penetrable) GPR88 agonist/activator with EC50 of 25 nM in GPR88 cAMP functional assays. |
|
V15926
|
TC-H 106
|
937039-45-7 |
Pimelic Diphenylamide 106 is a slow, tight-binding class I HDAC inhibitor (inhibits HDAC1, 2, and 3, IC50s 150 nM, 760 nM, and 370 nM, respectively) with no activity against class II HDACs. |
|
V1807
|
Timapiprant (OC000459)
|
851723-84-7 |
Timapiprant (formerly known as OC000459; OC-000459) is a novel, potent, selective, and orally bioactive prostanoid receptor 2 (DP2- also known as CRTH2)) antagonist with IC50 of 13 nM. |
|
V70308
|
Zelatriazin (TAK-041; NBI-1065846)
|
1929519-13-0 |
Zelatriazin (TAK-041; NBI-1065846) is a potent and specific GPR139 agonist/activator with EC50 of 22 nM. |
|
V75419
|
ZQ-16
|
376616-73-8 |
ZQ-16 is a potent and specific GPR84 agonist/activator with EC50 of 0.213 μM. |