|
V1779
|
PD123319
|
130663-39-7 |
PD 123319 [PD-123319; PD123319; (S)-(+)-PD 123319] is a novel, potent, and selective AT2 (angiotensin II) receptor antagonist with anti-hypertensive effects. |
|
V1776
|
Irbesartan (SR-47436; BMS-186295)
|
138402-11-6 |
Irbesartan (formerly known as SR47436; BMS186295;SR-47436; BMS-186295; Avapro, Aprovel, Karvea) is a highly potent and specific angiotensin II type 1 (AT II-1) receptor antagonist/ARB approved as an antihypertension drug. |
|
V1774
|
Enalaprilat Dihydrate (MK-422)
|
84680-54-6 |
EnalaprilatDihydrate(also known as MK422; MK 422; MK-422; Epaned, Vasotec, Vasotec IV), the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor approved for the treatment of hypertension, diabetic nephropathy, and chronic heart failure. |
|
V1792
|
Captopril (SQ-14534; SA333)
|
62571-86-2 |
Captopril (SQ 14225; SA333)is a potent angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM. |
|
V1785
|
Quinapril HCl (CI-906)
|
82586-55-8 |
Quinapril HCl (formerly CI-906, PD-109452-2; Acequin; Korec;Accupril; Accuprin; Accupril), the hydrochloride salt form of quinapril which is the prodrug of quinaprilat, is an angiotensin-converting enzyme/ACE inhibitor with anti-hypertensive effects. |
|
V1772
|
Candesartan (CV 11974)
|
139481-59-7 |
Candesartan (also known as CV-11974; Blopress, Atacand, Amias, Ratacand)is an approved antihypertensive drug acting as an AT II/angiotensin II receptor antagonist with IC50 of 0.26 nM. |
|
V1784
|
Candesartan Cilexetil (CV 11974)
|
145040-37-5 |
Candesartan Cilexetil (formerly TCV-116;CV11974; CV-11974; Atacand), an ester prodrug ofCandesartan,is an antihypertensive drug acting as an AT II/angiotensin II receptor antagonistwith anti-hypertensive effects. |
|
V1782
|
Perindopril Erbumine (S-9490-3)
|
107133-36-8 |
Perindopril Erbumine (also called S9490-3; Pirindopril; ACEON; Perindopril tert-butylamine; Perstarium), thetert-butylamine salt of perindopril,is a long acting and brain penetrant ACE (angiotensin-converting enzyme) inhibitor with anti-hypertensive effects. |
|
V1781
|
Olmesartan Medoxomil (CS 866)
|
144689-63-4 |
Olmesartan Medoxomil (formerly CS-866;Olmetec; Azor; Benicar;Olsertain), the medoxomil ester prodrug form of Olmesartan, is a potent and selective angiotensin II type 1/AT1 receptor antagonist with anti-hypertensive effects. |
|
V1775
|
Telmisartan (BIBR 277)
|
144701-48-4 |
Telmisartan (formerly BIBR-277;BIBR 277; BIBR277;Kinzalmono; Micardis)is along lasting angiotensin II receptor antagonist (ARB) approved for use in the management of hypertension. |
|
V1780
|
Temocapril
|
111902-57-9 |
Temocapril (CS-622;CS622;temocaprilum; Aceco) is a potent and long-acting angiotensin-converting enzyme (ACE) inhibitor, approved for use (not in the USA) in the treatment of hypertension. |
|
V1773
|
Losartan Potassium (DuP 753)
|
124750-99-8 |
Losartan Potassium (formerly DuP-753; MK-954; DuP753;MK954;Cozaar; Lorzaar; Losaprex), thepotassium salt of losartan, is an oral, selective, and non-peptide angiotensin II receptor antagonist approved as an antihypertensive drug. |
|
V1778
|
LCZ696 (Sacubitril-Valsartan)
|
936623-90-4 |
LCZ696 (LCZ-696; LCZ 696; Entresto; Sacubitril mixture with Valsartan), the combination of valsartan with sacubitril in 1:1 molar ratio, is an orally bioavailable and dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) approved in 2015 for the treatment of hypertension and heart failure. |
|
V1797
|
Eprosartan Mesylate (SKF-108566J)
|
144143-96-4 |
Eprosartan Mesylate(SKF-108566J) is a potent and nonpeptide angiotensin II receptor antagonist with IC50 of 9.2 and 3.9 nM in rat and human adrenal cortical membranes, respectively. |
|
V1789
|
Imidapril HCl (TA-6366)
|
89396-94-1 |
Imidapril HCl (TA-6366; TA-6366; Tanatril), the hydrochloride salt of imidapril,is a potent angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, approved in 1993 for use as an antihypertensive drug and for the treatment of chronic heart failure. |
|
V1791
|
Temocapril HCl
|
110221-44-8 |
Temocapril HCl is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, it is used for the treatment of hypertension. |
|
V1795
|
Moexipril HCl (RS-10085)
|
82586-52-5 |
Moexipril HCl (RS-10085) is a potent and orally bioactive nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure. |
|
V1787
|
Benazepril HCl (CGS14824A)
|
86541-74-4 |
Benazepril HCl (formerly CGS 14824A;CGS-14824-A;Briem; Cibacène; Cibacen; Labopal; Lotensin), the hydrochloride salt of Benazepril which is a prodrug that can bemetabolized to its active formbenazeprilat,is a potent angiotensin I converting enzyme (ACE) inhibitor that has beenwidelyused primarily in treatment of hypertension. |
|
V1796
|
Fosinopril Sodium (SQ28555)
|
88889-14-9 |
Fosinopril Sodium (also known as SQ28555), the ester prodrug offosinoprilat, is a potent angiotensin-converting enzyme (ACE) inhibitor that is used for the treatment of hypertension and some types of chronic heart failure. |
|
V1777
|
Valsartan (CGP-48933)
|
137862-53-4 |
Valsartan (formerly CGP-48933; CGP48933;Diovan, Prova, Tareg,Miten, Nisis, Vals, Walsarta), an approved antihypertensive drug, is a potent andselective angiotensin II receptor antagonist that isused for the treatment ofhigh blood pressure and congestive heart failure. |