yingweiwo

Dopamine Receptor

Dopamine Receptor

In the central nervous system (CNS) of vertebrates, dopamine receptors are a class of G protein-coupled receptors that are widely distributed. The main endogenous ligand for dopamine receptors is the neurotransmitter dopamine. Numerous neurological functions, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as the modulation of neuroendocrine signaling, are associated with dopamine receptors.Numerous neuropsychiatric disorders have abnormal dopamine receptor signaling and dopaminergic nerve function at their core. Dopamine receptors are therefore typical neurologic drug targets; psychostimulants are typically indirect agonists of dopamine receptors, whereas antipsychotics are frequently dopamine receptor antagonists. Dopamine receptors come in at least five different subtypes: D1, D2, D3, D4, and D5. The D2, D3, and D4 dopamine receptors are members of the D2-like family, whereas the D1 and D5 receptors belong to the D1-like family.

Dopamine Receptor related products

Structure Cat No. Product Name CAS No. Product Description
氟哌啶醇 V22058 Haloperidol 52-86-8 Haloperidol (R1625; Eukystol; HSDB-3093; Haldol; Serenace; Aloperidin) is a potent antipsychotic medication acting as adopamine D2 receptor antagonist.
氟氯波必利 V8563 Fluoroclebopride 154540-49-5 Fluoroclebopride is useful chemical for PET image study.
氟派利多 V20255 Droperidol 548-73-2 Droperidol (Dridol; Properidol; Dehydrobenzperidol; Inapsine) is a novel and potent D1DR and D2DR inhibitor with anti-emetic, sedative and anti-anxiety activities.It is also an antidopaminergic drug that can be used as an antiemetic and antipsychotic.
氨磺必利盐酸盐 V11154 Amisulpride HCl 81342-13-4 Amisulpride HCl (Barhemsys; Solian; Amazeo; Aminosultopride; Amipride; Amival; Deniban; Amisulprida; Soltus; DAN-2163; Sulpitac; Sulprix), the hydrochloride salt of Amisulpride, is an atypical antipsychotic medication approved for treating psychosis in schizophrenia and episodes of mania in bipolar disorders.
氯普噻吨 V1259 Chlorprothixene 113-59-7 Chlorprothixene (Paxyl; Rentovet; Truxal; Ro 4-0403; N-714; MK-184; Taractan; Tarasan), an typical antipsychotic drug of the thioxanthene class, is an antagonist of dopamine and histamine receptors with potential antipsychotic, sedative and antiemetic activity.
氯氮平氮氧化合物 V9293 Clozapine N-oxide 34233-69-7 Clozapine N-oxide is a major metabolite of Clozapine and an agonist of human designer muscarinic receptors (DREADDs).
溴哌利多 V17137 Bromperidol (Impromen; R-11333) 10457-90-6 Bromperidol (Impromen; R11333),a butyrophenone derivative, is potent and long-term maintenance treatment for schizophrenia.
甲磺酸培高利特 V1268 Pergolide Mesylate (LY127809) 66104-23-2 Pergolide Mesylate (Permax; Pergotoliderived; LY127809; LY-127809), the mesylate salt of Pergolide, is a novel and potent antiparkinsonian agent which acts as a dopaminergic agonist.
甲磺酸溴隐亭 V17086 Bromocriptine Mesylate (CB-154) 22260-51-1 Bromocriptine Mesylate(CB154) is a dopamine D2/3 agonist (with pKi of 8.05±0.2 for D2) for the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.
甲磺酸苯扎托品 V1248 Benztropine mesylate 132-17-2 Benztropine mesylate (NSC-42199; ST-50997629; NSC 42199; ST 50997629; Cogentin; MLS000737056), the mesilate salt of Benztropine, is a highly potent dopamine transporter (DAT) inhibitor used for the treatment of symptoms of Parkinson's disease such as involuntary tremor and dystonia.
盐酸S-(-)-依替必利 V9611 Eticlopride HCl 97612-24-3 Eticlopride HCl (FLB131; FLB-131) is a potent antipsychotic agent acting asa selective dopamine D2‐like receptor antagonist.
盐酸丁卡因 V1247 Tetracaine HCl 136-47-0 Tetracaine HCl (also called Amethocalne; Butylocaine; Curtacain; Decicain; Gingicain; PantocaineM; Intercaine; Leocaine; Menonasal; Niphanoid), thehydrochloride salt form of tetracaine, is a local anaesthetic and a channel function allosteric inhibitor.
盐酸卡利拉嗪 V2902 Cariprazine HCl 1083076-69-0 Cariprazine HCl(formerly MP-214; RGH-188; MP214; RGH188; Vraylar; Reagila), thehydrochloride salt of cariprazine, is an antipsychotic medication that has been approved for the treatment of schizophrenia, as well as for bipolar disorder (manic/mixed and depressive episodes), and as an adjunctive agent for the treatment of major depressive disorder.
盐酸多巴胺 V1269 Dopamine HCl 62-31-7 Dopamine HCl (formerly Intropin; Dopamine HCl; ASL 279; ASL279; P 498; 3-Hydroxytyramine, ASL-279 and Intropin), the hydrochloride salt of dopamine, is an endogenous catecholamine neurotransmitter found in a wide variety of animals, it is a dopamine D1-5 receptors agonist.
盐酸安非他酮 V1250 Amfebutamone HCl 31677-93-7 Amfebutamone HCl (Bupropion, Wellbutrin, Zyban; BW-323; NSC315851; NSC-315851), the hydrochloride salt of Amfebutamone, is a potent and selective norepinephrine-dopamine reuptake inhibitor used as an antidepressant and for smoking cessation.
盐酸延胡索乙素 V60107 Tetrahydropalmatine hydrochloride 6024-85-7 Tetrahydropalmatine (also known as DL-Tetrahydropalmatine) hydrochloride has analgesic properties. Tetrahydropalmatine hydrochloride prevents a rat epileptic seizure by blocking the release of dopamine from amygdaloid.
盐酸普拉克索 V1261 Pramipexole 2HCl Monohydrate 191217-81-9 Pramipexole 2HCl monohydrate (formerly known as SND 919; (S)-Pramipexole; trade name Mirapex among others) is the dihydrochloride salt and hydrated form of of pramipexole which isa potent agonist of the Gαi-linked dopamine receptors D2, D3, and D4 with neuroprotective effects.
盐酸普拉克索 V28566 Pramipexole 2HCl ((S)-Pramipexole HCl) 104632-25-9 Pramipexole 2HCl (also known as SND 919; (S)-Pramipexole HC), an agonist of the Gαi-linked dopamine receptors D2, D3, and D4, is a potent dopamine agonist of the non-ergoline class that is used for the treatment of Parkinsons disease (PD) and restless legs syndrome (RLS).
盐酸曲美苄胺 V2067 Trimethobenzamide HCl (Ro 2-9578) 554-92-7 rimethobenzamide (also known as Ro 2-9578; trade names Tebamide, Tigan), a blocker of the D2 receptor, is a potent antiemetic that is used to prevent nausea and vomiting.
盐酸氟奋乃静 V21149 Fluphenazine HCl 146-56-5 FluphenazineHCl, the hydrochloride salt of Fluphenazine, is a novel and potent antipsychotic agent acting as adopamine D2 receptor inhibitor.
Contact Us