In the central nervous system (CNS) of vertebrates, dopamine receptors are a class of G protein-coupled receptors that are widely distributed. The main endogenous ligand for dopamine receptors is the neurotransmitter dopamine. Numerous neurological functions, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as the modulation of neuroendocrine signaling, are associated with dopamine receptors.Numerous neuropsychiatric disorders have abnormal dopamine receptor signaling and dopaminergic nerve function at their core. Dopamine receptors are therefore typical neurologic drug targets; psychostimulants are typically indirect agonists of dopamine receptors, whereas antipsychotics are frequently dopamine receptor antagonists. Dopamine receptors come in at least five different subtypes: D1, D2, D3, D4, and D5. The D2, D3, and D4 dopamine receptors are members of the D2-like family, whereas the D1 and D5 receptors belong to the D1-like family.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V71726 | UCM-1306 (2-(Fluoromethoxy)-4'-(S-methylsulfonimidoyl)-1,1'-biphenyl) | 2258608-78-3 | UCM-1306 is an orally bioavailable allosteric modulator (PAM) of the human dopamine D1 receptor. |
|
V71740 | Vanicoside E | 208707-91-9 | Vanicoside E is an antioxidant and anticancer agent. |
|
V71207 | Zicronapine fumarate (Lu 31-130 fumarate) | 170381-17-6 | Zicronapine (Lu 31-130) fumarate is an antipsychotic drug with strong precognitive effects in animal models and may be used to treat many neurological and psychiatric disorders. |
|
V71782 | Zuclopenthixol-d4 succinate | 1246833-97-5 | Zuclopenthixol-d4 (succinate) is the deuterium labelled form of Zuclopenthixol. |
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