The acetylcholine receptors known as mAChRs (muscarinic acetylcholine receptors) are found in the cell membranes of some neurons and other cells. The primary end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system is one of their many functions. Because they are more sensitive to muscarine than to nicotine, mAChRs are so named. Nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also significant in the autonomic nervous system, are their counterparts. Numerous medications and other substances, such as scopolamine and pilocarpine, act as selective agonists or antagonists on these two different receptors. The brain and the autonomic ganglia are both rich sources of the neurotransmitter acetylcholine (ACh).
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V70537 | PTACoxalate | 201939-40-4 | PTAC oxalate is a selective muscarinic receptor ligand. |
|
V32273 | Racanisodamine | 17659-49-3 | Racanisodamine is a racemate of anisodamine and has similar pharmacological effects. |
|
V3863 | Revefenacin | 864750-70-9 | Revefenacin (formerly known as TD-4208; GSK-1160724; trade name: Yupelri) is a long-acting, potent mAChR (muscarinic acetylcholine receptor) antagonist with a high affinity on M3 receptor with a Ki of 0.18 nM. |
|
V14557 | Scopolamine HCl | 55-16-3 | Scopolamine HCl (Hyoscine),the hydrochloride salt ofScopolamine, isa drug approved for the treatment of motion sickness and postoperative nausea and vomiting. |
|
V85037 | SM 21 maleate | 155059-42-0 | |
|
V3721 | Solifenacin (YM905) | 242478-37-1 | Solifenacin (YM-905; Vesikur; Vesicare) is a novel and potent muscarinic receptor antagonist that has beenapproved for the treatment of overactive bladder. |
|
V79282 | Solifenacin-d7 hydrochloride | Solifenacin-d7 ( HCl) is the deuterated form of Solifenacin HCl. | |
|
V70548 | Tazomeline | 131987-54-7 | Tazomeline is a selective M1 muscarinic receptor agonist. |
|
V2825 | TBPB | 634616-95-8 | TBPB[1-(1-2-methylbenzyl)-1,4-bipiperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one] is a novel and highly selectiveallosteric agonist Muscarinic M1 receptor (mAChR) withEC50 of 289 nM. |
|
V70514 | Telenzepine dihydrochloride | 147416-96-4 | Telenzepine di-HCl is a selective and orally bioactive muscarinic M1 receptor antagonist (inhibitor) with a Ki of 0.94 nM. |
|
V15146 | Tiotropium bromide | 136310-93-5 | Tiotropium Bromide (BA679BR; BA-679BR; PUR-0200; PUR0200; Spiriva) is an approved anticholinergic and bronchodilator medication used as a long-acting bronchodilator for the treatment of chronic obstructive pulmonary disease (COPD). |
|
V70513 | Tiotropium bromide monohydrate (Tiotropium bromide monohydrate; BA-679 BR monohydrate) | 411207-31-3 | Tiotropium bromide (BA-679 BR) monohydrate is a long-acting muscarinic receptor blocker (antagonist). |
|
V70529 | Tiotropium-d3 bromide (BA679 BR-d3) | 1127226-56-5 | Tiotropium-d3 (bromide) is the deuterated form of Tiotropium (Bromide). |
|
V16571 | Tolterodine | 124937-51-5 | Tolterodine (also known as PNU-200583E) is a tartrate salt of tolterodine that is a potent and competitive muscarinic receptor antagonist. |
|
V70551 | Tolterodine-d14 hydrochloride ((R)-(+)-Tolterodine-d14 hydrochloride; (+)-Tolterodine-d14 hydrochloride; (R)-Tolterodine-d14 hydrochloride; PNU-200583-d14 hydrochloride) | 1217645-16-3 | Tolterodine-d14 (HCl) is the deuterium labelled form of Tolterodine HCl. |
|
V81619 | Trihexyphenidyl-d5 hydrochloride | Trihexyphenidyl-d5 ( HCl) is the deuterated form of Trihexyphenidyl ( HCl). | |
|
V70552 | Tropicamide-d3 (Ro 1-7683-d3) | 2673270-13-6 | Tropicamide-d3 is the deuterated form of Tropicamide. |
|
V78932 | Trospium-d8 chloride (trospium d8 chloride) | Trospium-d8 (chloride) is the deuterated form of Trospium chloride. | |
|
V3643 | Umeclidinium bromide | 869113-09-7 | Umeclidinium bromide (formerly GSK-573719; GSK573719A; Incruse Ellipta) is a novel and inhaled long-acting muscarinic antagonist (LAMA) with the potential for treatment of pulmonary diseases (e.g. COPD). |
|
V76389 | Umeclidinium-d10 bromide (GSK573719A-d10) | Umeclidinium-d10 (bromide) is the deuterated form of Umeclidinium bromide. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
