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Opioid Receptor

Opioid Receptor

Opioid ligands are a class of G protein-coupled receptors known as opioid receptors. Dynorphins, enkephalins, endorphins, endomorphins, and nociceptin are examples of endogenous opioids. There are many opioid receptors in the brain, as well as in the spinal cord and digestive system. The body has molecules or sites called opioid receptors that are triggered by opioid substances. Opioid receptors prevent impulses from traveling along excitatory pathways in the human body.The serotonin, catecholamine, and substance P pathways are some of these pathways, and they are all thought to play a role in pain perception and feelings of wellbeing. Mu, delta, and kappa receptors are additional subclassifications of opioid receptors. While each class has its own unique way of acting, they all have some fundamental things in common. The potassium pump mechanism, which is present on the plasma membrane of most cells, powers them all.

Opioid Receptor related products

Structure Cat No. Product Name CAS No. Product Description
[DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) V69951 [DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) 75921-88-9 [DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) is an opioid peptide (dynorphinl-13, DYN) analogue found in porcine pituitary gland extract.
[DAla2] Dynorphin A (1-13), amide (porcine) V69923 [DAla2] Dynorphin A (1-13), amide (porcine) 79985-43-6 [DAla2] Dynorphin A (1-13), amide (porcine) is a bioactive peptide.
[DPen2, Pen5] Enkephalin V69927 [DPen2, Pen5] Enkephalin 88373-72-2 [DPen2, Pen5] Enkephalin is a δ-opioid receptor selective analog of [Leu5]-Enkephalin .
[DPro10] Dynorphin A (1-11), porcine V69949 [DPro10] Dynorphin A (1-11), porcine 94596-26-6 [DPro10] Dynorphin A (1-11), porcine is an N-alkylated analogue and a potent kappa-opioid receptor agonist/activator with a Ki of 0.13 nM.
[DPro10] Dynorphin A (1-11), porcine hydrochloride V77476 [DPro10] Dynorphin A (1-11), porcine hydrochloride [DPro10] Dynorphin A (1-11), porcine HCl is an N-alkylated analogue and a potent kappa-opioid receptor agonist/activator with a Ki of 0.13 nM.
[Met5]-Enkephalin, amide TFA (5-Methionine-enkephalin amide TFA) V69881 [Met5]-Enkephalin, amide TFA (5-Methionine-enkephalin amide TFA) 2918768-28-0 [Met5]-Enkephalin, amide TFA is a delta and zeta opioid receptor agonist (activator).
[Nphe1]Nociceptin(1-13)NH2 V69965 [Nphe1]Nociceptin(1-13)NH2 267234-08-2 [Nphe1]Nociceptin(1-13) NH2 is a Nociceptin/orphanin FQ (NC) endogenous ligand and a selective and competitive ociceptin receptor antagonist (inhibitor) without agonist activity.
[Nphe1]Nociceptin(1-13)NH2 TFA V77483 [Nphe1]Nociceptin(1-13)NH2 TFA [Nphe1]Nociceptin(1-13) NH2 TFA is an endogenous ligand of Nociceptin/orphanin FQ (NC) and is a selective and competitive ociceptin receptor antagonist (inhibitor) without agonist activity.
Ac-RYYRIK-NH2 V69954 Ac-RYYRIK-NH2 200959-48-4 Ac-RYYRIK-NH2 is a potent ORL1 partial agonist that works as an endogenous ligand of ORL1 in CHO cells (Kd=1.5 nM).
Ac-RYYRIK-NH2 TFA V77780 Ac-RYYRIK-NH2 TFA Ac-RYYRIK-NH2 TFA is a potent ORL1 partial agonist that works as an endogenous ligand of ORL1 in CHO cells (Kd=1.5 nM).
Ac-RYYRWK-NH2 V69952 Ac-RYYRWK-NH2 200959-47-3 Ac-RYYRWK-NH2 is a potent and specific nociceptin receptor (NOP) partial agonist.
Ac-RYYRWK-NH2 TFA V69908 Ac-RYYRWK-NH2 TFA 408305-09-9 Ac-RYYRWK-NH2 TFA is a potent and specific nociceptin receptor (NOP) partial agonist.
Acetalin-1 V85766 Acetalin-1 152274-67-4
Acetalin-3 V85916 Acetalin-3 152274-65-2
ADL5859 HCl V1276 ADL5859 HCl 850173-95-4 ADL5859 HCl (ADL 5859; ADL-5859),the hydrochloride salt of ADL5859, is a potent, orally bioavailable δ-opioid receptor agonist with important biological activity.
Alvimopan V3722 Alvimopan 156053-89-3 Alvimopan (also known as ADL 8-2698; LY 246736; HSDB-7704) is a novel peripheral micro opioid antagonist in clinical development for the management of post-operative ileus and opioid-induced bowel dysfunction.
Alvimopan dihydrate V3724 Alvimopan dihydrate 170098-38-1 Alvimopan (also known as ADL 8-2698; LY 246736; HSDB-7704) is a novel peripheral micro opioid antagonist in clinical development for the management of post-operative ileus and opioid-induced bowel dysfunction.
Alvimopan monohydrate V3723 Alvimopan monohydrate 1383577-62-5 Alvimopan (also known as ADL 8-2698; LY 246736; HSDB-7704) is a novel peripheral micro opioid antagonist in clinical development for the management of post-operative ileus and opioid-induced bowel dysfunction.
Anrikefon acetate (HSK21542 acetate) V69937 Anrikefon acetate (HSK21542 acetate) 2584931-05-3 Anrikefon (HSK21542) acetate is a kappa opioid receptor agonist (activator) with pain-relief effects.
AR-M 1000390 HCl V2073 AR-M 1000390 HCl 209808-47-9 AR-M 1000390 hydrochloride (the hydrochloric acid of ARM-390; AR-M1000390) is a potent, highly selective agonist of δ opioid receptor that can induce insulin depletion in the rat and RINm5F cells.
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