As the primary component of the amyloid plaques seen in the brains of Alzheimer patients, amyloid- (A) refers to peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease. The amyloid precursor protein (APP), which is cut by specific enzymes to produce A, produces the peptides. Amyloid molecules can group together to create a variety of flexible, soluble oligomers.A amyloid-peptide buildup results from excessive A production or malfunctioning clearance mechanisms. Amyloid- forms diffuse and neuritic plaques in the parenchyma and blood vessels by self-aggregating into oligomers of various sizes. Strong synaptotoxins, proteasome inhibition, mitochondrial inhibition, alteration of intracellular Ca2+ levels, and induction of inflammatory processes are all characteristics of amyloid-oligomers and plaques. Neuronal dysfunction is also thought to be influenced by the loss of A's typical physiological functions.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V71416 | Aβ/tau aggregation-IN-3 | 1210750-32-5 | Aβ/tau aggregation-IN-3 is a potent amyloid aggregation inhibitor (antagonist) with IC50 of 0.85 μM as measured by Aβ-thioflavin T (Aβ-ThT) functional aggregation. |
|
V85063 | Aβ1–42 aggregation inhibitor 2 | ||
|
V71390 | Aβ42 agonist-1 | 50635-12-6 | Aβ42 agonist-1 (compound 7a) is a small molecule compound that can promote Aβ42 aggregation. |
|
V71376 | Aβ42 agonist-2 | 6314-40-5 | Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. |
|
V85095 | Aβ42-IN-4 | 2387822-02-6 | |
|
V84203 | Aβ42-IN-5 | ||
|
V71360 | Bapineuzumab | 648895-38-9 | Bapineuzumab is an anti-β-amyloid (APP) monoclonal antibody (mAb). |
|
V4468 | Bavachinin (BVC; 7-O-Methylbavachin; Bavachinin A) | 19879-30-2 | Bavachinin(BVC; 7-O-Methylbavachin; Bavachinin A) is a naturally occuring compound isolated from the fruit of the traditional Chinese herb Fructus Psoraleae (FP). |
|
V71445 | Beta-Amyloid (15-21) (Beta-Amyloid (15-21)) | 365537-52-6 | β-amyloid (15-21) is a fragment of the β-amyloid peptide with potential role in the neurological field. |
|
V71413 | BIBD-124 | 2716871-93-9 | BIBD-124 binds amyloid (Aβ) plaques with IC50 of 9.51 nM. |
|
V71405 | Biotin-Ahx-β-Amyloid (1-40) | 1802086-72-1 | Biotin-Ahx-β-Amyloid (1-40) is a biologically active peptide. |
|
V78468 | Biotin-β-amyloid (1-28) (Biotin-amyloid β-protein (1-28)) | Biotin-β-amyloid (1-28) (Biotin-amyloid β-protein (1-28)) is a biotin-labeled β-Amyloid (1-28). | |
|
V78469 | Biotin-β-Amyloid (1-42), human TFA (Biotin-amyloid β-peptide (1-42) (human) TFA) | Biotin-β-Amyloid (1-42), human TFA (Biotin-Amyloid β-Peptide (1-42) (human) TFA) is biotin-labeled β-Amyloid (1-42), human TFA. | |
|
V78470 | Biotin-β-Amyloid (17-40) | Biotin-β-Amyloid (17-40) is an N-terminally tagged biotinylated amyloid β-Amyloid (17-40) peptide. | |
|
V71398 | Biotinyl-Ahx-Amyloid β-Protein (1-42) | 1872440-40-8 | Biotinyl-Ahx-Amyloid β-Protein (1-42) is a biotinylated β-Amyloid (1-42), human (TFA). |
|
V78464 | Biotinyl-Ahx-Amyloid β-Protein (1-42) (ammonium) | Biotinyl-Ahx-Amyloid β-Protein (1-42) ammonium is an N-terminal biotin-labeled Amyloid β-Protein (1-42). | |
|
V78465 | Biotinyl-Amyloid β-Protein (1-42) (ammonium) | Biotinyl-Amyloid β-Protein (1-42) ammonium is a biotinylated Amyloid β-Protein (1-42). | |
|
V71370 | Birtamimab (NEOD001) | 1608108-91-3 | Birtamimab (NEOD001) is an investigational monoclonal antibody (mAb) that specifically and selectively targets and clears amyloid. |
|
V86132 | Buntanetap L-Tartrate ((+)-Phenserine L-Tartrate; ANVS401 L-Tartrate) | 865795-23-9 | |
|
V77153 | Chemerin-9 (149-157) (TFA) | Chemerin-9 (149-157) TFA is a potent agonist of chemokine-like receptor 1 (CMKLR1). |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
