The acquired immunodeficiency syndrome (AIDS), a condition in which the immune system gradually fails and life-threatening opportunistic infections and cancers proliferate, is brought on by the lentivirus (a subgroup of retrovirus) known as HIV. HIV infection happens when blood, semen, vaginal fluid, pre-ejaculate, or breast milk are shared. HIV can be found in these bodily fluids as both free virus particles and as a virus inside infected immune cells.Important immune system components like helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells are all infected by HIV. Apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells are some of the mechanisms by which HIV infection results in low levels of CD4+ T cells. Cell-mediated immunity is lost and the body becomes progressively more vulnerable to opportunistic infections when CD4+ T cell counts fall below a critical threshold.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V51983 | HIV-1 inhibitor-8 | 2826996-78-3 | HIV-1 inhibitor-8 is an orally bioactive, low-toxic and effective HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). |
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V54281 | HIV-1 inhibitor-9 | 2708201-36-7 | HIV-1 inhibitor-9 was found to be potent at low nanomolar levels against wild-type (WT) HIV-1 strains or multiple NNRTI-resistant strains. |
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V79133 | HIV-1 protease-IN-10 | HIV-1 protease-IN-10 (Compound 2) has HIV-1 latency reversal activity (IC50= 0.22 μM). | |
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V34678 | HIV-1 TAT (48-60) | 220408-24-2 | HIV-1 TAT (48-60) is a cell-permeable (penetrable) polypeptide extracted from human immunodeficiency virus (HIV)-1 protein residues 48-60. |
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V58678 | HIV-2 Peptide | 172486-63-4 | HIV-2 Peptide is a bioactive peptide discovered by peptide screening. |
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V85445 | HIV-IN-10 | 2413866-14-3 | |
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V54301 | HIV-IN-8 | 130286-75-8 | HIV-IN-8 (Compound 9) is an HIV inhibitor. |
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V54256 | Hypoglaunine D | 220751-00-8 | Hypoglaunine D is an analog of Triptonine B and an anti-HIV compound. |
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V79786 | ICeD-2 | ICeD-2 is a cell death inducer that induces cell death in HIV-1-infected cells. | |
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V51953 | Ilimaquinone | 71678-03-0 | Ilimaquinone is a marine sponge metabolite that exerts anti-tumor activity through the GADD153-mediated signaling pathway. |
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V51951 | IMB-301 | 64009-84-3 | IMB-301 is a specific HIV-1 replication inhibitor that can bind to hA3G (human APOBEC3G), block hA3G-Vif interaction, and inhibit Vif-mediated hA3G degradation. |
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V4108 | Indinavir | 150378-17-9 | Indinavir (IDV; formerly DRG-0233;MK639 and L-735524; Crixivan) is an inhibitor of HIV protease approved for use as a component of highly active antiretroviral therapy to treat HIV/AIDS. |
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V4109 | Indinavir sulfate | 157810-81-6 | Indinavir sulfate (IDV; formerly known as MK-639;DRG-0233;L735524; trade name Crixivan), the sulfate salt of indinavir, is a potent and specific HIV protease inhibitor with antiviral effects and good oral bioavailability. |
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V34796 | Influenza antiviral conjugate-1 | 2567770-65-2 | Influenza antiviral conjugate-1 (INT-2) is an HIV inhibitor (antagonist) with potent cell fusion inhibition. |
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V54252 | Ingenol-3-palmitate | 52557-26-3 | Ingenol-3-palmitate is a euphorbia diterpene, a naturally occurring compound extracted from the roots of Euphorbia ebracteolata. |
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V30732 | Inosine pranobex (Imunovir; Delimmun; Groprinosin) | 36703-88-5 | Inosine pranobex (Imunovir; Delimmun; Groprinosin),a combinatinon of inosine, acetamidobenzoic acid,and dimethylaminoisopropanol, is a novel, potent, broad-spectrum antiviral agent potentially useful for HIV/AIDs infection. |
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V54274 | Interiorin | 119139-55-8 | Interiorin can be extracted from Kadsura heteroclita and has moderate anti-HIV (Human Immunodeficiency Virus) activity with EC50 of 1.6 lg/mL. |
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V4389 | ISLATRAVIR | 865363-93-5 | Islatravir (formerly known as MK-8591; 4′-ethynyl-2-fluoro-2′-deoxyadenosine; EFdA;ISL) is a novel and potent anti-HIV-1agent which acts as an NRTTI (nucleosidereverse transcriptaseinhibitor) with anti-HIV activities. |
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V32709 | Isoapetalic acid | 34366-34-2 | Isoapetalic acid (compound 4) is a potent anti-HIV (Human Immunodeficiency Virus) agent. |
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V54266 | Kadsuracoccinic acid A | 1016260-22-2 | Kadsuracoccinic acid A is a tetracyclic natural compound extracted from the stems of black tiger (Kadsura coccinea). |
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